The relativity of EGFR and autophagy in the regulatingradiation sensitivity of brain glioma cells

LI Feng; LONG Linmei; LIANG Zhongqin

您当前的位置：

首页 >

文章列表页 >

The relativity of EGFR and autophagy in the regulatingradiation sensitivity of brain glioma cells

更新时间：2023-03-27

- The relativity of EGFR and autophagy in the regulatingradiation sensitivity of brain glioma cells
- Journal of Radiation Research and Radiation Processing Vol. 29, Issue 4, Pages: 197-201(2011)
- 作者机构：
  
  1.苏州大学06级临床医学七年制　苏州　215123
  2.苏州大学医学部药理学系　苏州　215123
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
LI Feng, LONG Linmei, LIANG Zhongqin. The relativity of EGFR and autophagy in the regulatingradiation sensitivity of brain glioma cells. [J]. Journal of Radiation Research and Radiation Processing 29(4):197-201(2011)
DOI：

LI Feng, LONG Linmei, LIANG Zhongqin. The relativity of EGFR and autophagy in the regulatingradiation sensitivity of brain glioma cells. [J]. Journal of Radiation Research and Radiation Processing 29(4):197-201(2011) DOI：

摘要

放射治疗是目前脑胶质瘤综合治疗最重要的治疗手段之一，但恶性脑胶质瘤产生的耐辐射作用限制了它的临床作用。因此，寻找胶质瘤耐辐射新机制具有十分重要的意义。研究表明，在脑胶质瘤放射治疗中，表皮生长因子受体（Epidermal growth factor receptor，EGFR）与脑胶质瘤的辐射敏感性，自噬与肿瘤辐射抗性产生机制相关；EGFR与自噬的发生存在某种联系，这种联系是否能作为增强脑胶质瘤辐射敏感性的理想靶点有待进一步深入研究。

Abstract

Radiotherapy is one of the most important methods in the combination therapy against glioma, but resistance of the malignant glioma to radiation limits its clinical contribution. Therefore, it makes great sense to study new mechanisms of radio-resistance. Recent studies show that there is a relationship between EGFR and autophagy in human glioma radiotherapy. More investigations will be needed to select ideal target to enhance the radio-sensitivity of glioma by use of the relationship.

关键词

表皮生长因子受体自噬脑胶质瘤辐射

Keywords

Epidermal growth factor receptor (EGFR)AutophagyGliomaRadiation

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Trends and levels of environmental radiation in Shenzhen from 2011 to 2020

Review of the synthesis of semiconductor nanomaterials using ionizing radiation technology

Bioinformatics analysis of differentially expressed genes in irradiated non-small cell lung cancer

Effect of 0.4 mT power frequency magnetic field on the migration of human amniotic epithelial cells

Auto-detection method for random telegraph signal noise detection for CMOS active pixel sensors based on real-time thresholds

Related Author

No data

Related Institution

Shenzhen Ecological and Environmental Monitoring Center of Guangdong Province

College of Chemistry and Chemical Engineering, Hunan Normal University

College of Resources and Environment, Hunan Agricultural University

Institute of Nuclear Agricultural Science and Space Mutation Breeding, Hunan Academy of Agriculture Sciences

Department of Therapy of Nuclear Personnel, Navy Hospital

⁰