Evaluation of surface dose for intensity-modulated radiation therapy by the relative distance between tumor and surface
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Evaluation of surface dose for intensity-modulated radiation therapy by the relative distance between tumor and surface
Journal of Radiation Research and Radiation ProcessingVol. 26, Issue 2, Pages: 125-128(2008)
作者机构:
1.四川大学华西医院肿瘤中心放射物理技术中心 成都 610041
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WANG Shichao, FU Yuchuan, XIAO Jianghong, et al. Evaluation of surface dose for intensity-modulated radiation therapy by the relative distance between tumor and surface. [J]. Journal of Radiation Research and Radiation Processing 26(2):125-128(2008)
DOI:
WANG Shichao, FU Yuchuan, XIAO Jianghong, et al. Evaluation of surface dose for intensity-modulated radiation therapy by the relative distance between tumor and surface. [J]. Journal of Radiation Research and Radiation Processing 26(2):125-128(2008)DOI:
Evaluation of surface dose for intensity-modulated radiation therapy by the relative distance between tumor and surface
在使用调强技术治疗某些部位的肿瘤时,皮肤的急性毒性反应比传统的治疗方式严重,而治疗另外一些部位的肿瘤时却得到相反的结果。为了探讨调强技术治疗不同部位肿瘤引起不同皮肤反应的原因,本工作利用一个固体水体模,设计了一系列的调强治疗计划研究肿瘤与表面相对距离对皮肤表面剂量的影响,结果表明,肿瘤部位与表面的相对距离是一个明显的影响表面剂量分布的参数。使用调强治疗技术,肿瘤的部位越浅,需要的机器跳数(Monitor unit, MU)就越多,表面的剂量也越高,越有可能对皮肤造成辐射损伤。
Abstract
Intensity-modulated radiation therapy(IMRT) has been shown clinically to increase skin doses for some patients and to decrease skin doses for other patients. A set of IMRT plans for hypothetic targets in a solid-water phantom were designed to investigate the reasons. The results showed that the relative distance between tumor and surface was an important parameter which would affect surface dose strongly. The smaller distance would lead to the more monitor units (MUs), the higher dose at surface and the more probability for severe skin toxicity reaction.