PROTECTIVE EFFECTS OF ELEMENE ON LYMPHOCYTE OF IRRADIATED MICE AND ITS REGULATION

Liu Yongbiao; Su Liaoyuan; Kong Xiangrong

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PROTECTIVE EFFECTS OF ELEMENE ON LYMPHOCYTE OF IRRADIATED MICE AND ITS REGULATION

更新时间：2023-04-18

- PROTECTIVE EFFECTS OF ELEMENE ON LYMPHOCYTE OF IRRADIATED MICE AND ITS REGULATION
- Journal of Radiation Research and Radiation Processing Vol. 16, Issue 3, Pages: 161-164(1998)
- 作者机构：
  
  1.苏州医学院放射医学系　苏州　215007
- 作者简介：
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Liu Yongbiao, Su Liaoyuan, Kong Xiangrong. PROTECTIVE EFFECTS OF ELEMENE ON LYMPHOCYTE OF IRRADIATED MICE AND ITS REGULATION. [J]. Journal of Radiation Research and Radiation Processing 16(3):161-164(1998)
DOI：

Liu Yongbiao, Su Liaoyuan, Kong Xiangrong. PROTECTIVE EFFECTS OF ELEMENE ON LYMPHOCYTE OF IRRADIATED MICE AND ITS REGULATION. [J]. Journal of Radiation Research and Radiation Processing 16(3):161-164(1998) DOI：

摘要

应用单克隆抗体铺皿法分离受,60,Co ,γ,射线分次照射的小鼠脾脏L,3,T,4,、Lyt,2,和B细胞，测定榄香烯对以上3种亚群细胞和L,3,T,4,、Lyt,2,对B细胞,3,H-TdR掺入的影响；同时测定SOD活力和LPO含量。结果表明：榄香烯提高亚群细胞的辐射抗性，增强了L,3,T,4,对B细胞的辅助调节作用，提高脾脏SOD活力和降低LPO含量。

Abstract

The spleen lymphocytes in mice after fraction irradiation were separated into L,3,T,4,Lyt,2, and B cells by a panning method with monoclonal antibodies. The effects of elemene on function and regulation of lymphocyte subsets were studied by using ,3,H-TdR incorporation,the SOD activity and LPO content were measured. The results indicated that elemene could increase the radiation resistance of lymphoicyte subsets,enhance the helping effects of L,3,T,4, on B cell,increase spleen SOD activity and decrease LPO content. The formation of the mechanism of protection may be due to scavenging free radical and relieving the damage of target.

关键词

淋巴细胞亚群自由基过氧化反应γ全身照射榄香烯

Keywords

Lymphocyte subsetsFree radicalPeroxidationγ-ray whole body irradiationElemene

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