STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM <italic style="font-style: italic">β</italic>-RAYS AND <sup>60</sup>Co γ-RAYS

Zhang Liazhen; Wang Shoufang; Deng Zhicheng; Zhan Jianhai; Hao Yayi; Wang Haiyan; Chen Baowen; Xing Xiaohong

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STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND ⁶⁰Co γ-RAYS

更新时间：2023-04-23

- STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND ⁶⁰Co γ-RAYS
- Journal of Radiation Research and Radiation Processing Vol. 10, Issue 4, Pages: 240-242,251(1992)
- 作者机构：
  
  1.中国辐射防护研究院，太原　030006
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Zhang Liazhen, Wang Shoufang, Deng Zhicheng, et al. STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND ⁶⁰Co γ-RAYS. [J]. Journal of Radiation Research and Radiation Processing 10(4):240-242,251(1992)
DOI：

Zhang Liazhen, Wang Shoufang, Deng Zhicheng, et al. STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND ⁶⁰Co γ-RAYS. [J]. Journal of Radiation Research and Radiation Processing 10(4):240-242,251(1992) DOI：

摘要

介绍了用氚,β,射线和,60,Co γ射线离体照射G,0,期人淋巴细胞诱发染色体畸变的剂量效应关系（剂量范围为0—0.5 Gy）。实验表明：无论是氚,β,射线还是,60,Co γ射线所诱发的淋巴细胞染色体畸变均以染色体型畸变为主，诱发的双着丝粒体与剂量的关系均适合以Y=a+bD模式来表示。以,60,Co γ射线为参考辐射，以淋巴细胞染色体畸变为生物终点，测得氚的RBE值为2。

Abstract

Chromosomal aberration of human lymphocytes at G,0, phases of cell cycle induced by tritium ,β,-rays and ,60,Co γ-rays were investigated. Dose-response relationship has been observed (dose range from 0 to 0.5 Gy). The results showed that chromosomal type aberration is main aberration for both radiations and the data of dicentrics gave the best fit to the linear model respectively Y=- 0.0824+ 0.0555 D and Y=- 0.0719+0.0263 D. Taking ,60,Co γ-rays as a reference source, the RBE value of dicentrics for tritium ,β,-rays irradiation was estimated to be 2.

关键词

氚β射线60Co γ射线淋巴细胞染色体畸变相对生物效应

Keywords

Tritium β-rays60Co γ-raysLymphocytesChromosomes aberrationsRBE

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National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention

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STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND 60Co γ-RAYS

DOI：

摘要

Abstract

关键词

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references

STUDY ON RBE AND CHROMOSOME ABERRATION RATE IN HUMAN BLOOD LYMPHOCYTE IRRADIATED BY LOW DOSE TRITIUM β-RAYS AND ⁶⁰Co γ-RAYS