PREPARATION OF THERMO-SENSITIVE HYDROGEL AND CONTROLLED RELEASE

Wu Minghong; Chen Jie; Zhou Ruimin; Ma Zue-teh; Bao Borong

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PREPARATION OF THERMO-SENSITIVE HYDROGEL AND CONTROLLED RELEASE

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- PREPARATION OF THERMO-SENSITIVE HYDROGEL AND CONTROLLED RELEASE
- Journal of Radiation Research and Radiation Processing Vol. 15, Issue 1, Pages: 53-55(1997)
- 作者机构：
  
  1.上海大学射线应用研究所　上海　201800
  2.中国科学院上海原子核研究所　上海　2018001
- 作者简介：
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Wu Minghong, Chen Jie, Zhou Ruimin, et al. PREPARATION OF THERMO-SENSITIVE HYDROGEL AND CONTROLLED RELEASE. [J]. Journal of Radiation Research and Radiation Processing 15(1):53-55(1997)
DOI：

Wu Minghong, Chen Jie, Zhou Ruimin, et al. PREPARATION OF THERMO-SENSITIVE HYDROGEL AND CONTROLLED RELEASE. [J]. Journal of Radiation Research and Radiation Processing 15(1):53-55(1997) DOI：

摘要

通过在空气中预辐射聚丙烯多孔膜，将单体N-异丙基丙烯酰胺（NIPAAm）接枝到聚丙烯多孔膜的表面上，得到一种新型的具有良好的热敏性及机械性能的水凝胶。研究了各种因素对接枝反应的影响，考察了其热敏性能及表面形貌，通过改变温度可改变多孔膜孔径大小，并将其用于托马斯亮蓝分子的渗透及控释过程。

Abstract

N-isopropylacrylamide (NIPAAm) was grafted onto Polypropyrene ultrathinporous film by preirradiation grafting. A new kind of hydrogel with good mechanical strength and thermo-sensitivity was obtained. The factors which affect the grafting reaction were studied, and the surface micro-structure were observed. The aperture diameter of polypropyrene ultrathinporous could be controlled by temperature, and the grafted polypropyrene was used as penetrating and controlled release of drug deliverly.

关键词

聚丙烯N-异丙基丙烯酰胺辐射接枝热敏材料缓释控制

Keywords

PolypropyreneN-isopropylacrylamideIrradiation graftingThermo-sensitive materialControlled release

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Radiation preparation and characterization of temperature- and pH-sensitive hydrogel of N-isopropylacrylamide/β-cyclodextrin copolymer

尼龙滤布共辐射接枝N-异丙基丙烯酰胺研究

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School of Environmental and Chemical Engineering, Shanghai University

(Shanghai Institute of Applied Physics, Chinese Academy of Sciences,,)

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