Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice

WANG Zhen; LUO Shishi; NIU Lei; NAI Aitao; XU Yang; LIU Zhenghai; HE Jie; HE Shuya; ZHONG Xiaolin; WAN Wei; CAO Wenyu

doi:10.11889/j.1000-3436.2019.rrj.37.010301

您当前的位置：

首页 >

文章列表页 >

Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice

RADIOBIOLOGY AND RADIOMEDICINE | 更新时间：2025-03-03

- Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice
- “The latest research has found that ionizing radiation may activate astrocytes in the hippocampus of mice, induce the release of inflammatory factors, and lead to cognitive dysfunction.”
- Journal of Radiation Research and Radiation Processing Vol. 37, Issue 1, Pages: 10301-25(2019)
- 作者机构：
  
  1.南华大学医学院应用解剖与生殖医学研究所衡阳 421001
  2.南华大学附属第一医院肿瘤放疗科衡阳 421001
  3.南华大学医学院生理教研室衡阳 421001
  4.南华大学医学院病理教研室衡阳 421001
  5.南华大学公共卫生学院放射医学教研室衡阳 421001
  6.南华大学附属第一医院临床医学研究所衡阳 421001
- 作者简介：
  
  WANG Zhen (female) was born in July 1990, and graduated from University of South China in 2015. Now she is a master candidate in the Clinical Anatomy and Reproductive Medicine Application Institute of University of South China, E-mail:736887612@qq.com
  WAN Wei, associate professor, master’s supervisor, E-mail:david-wan@163.com;Ph.D
  CAO Wenyu, Lecturer, E-mail: marksman0@163.com
- 基金信息：
  
  the Hunan Provincial Natural Science Foundation of China(2018JJ3460;2018JJ3429;2018JJ3464);the Hunan Provincial Natural Science Fund Provincial and Municipal Joint Fund Project(2018JJ4034);the Hunan Provincial Education Department Foundation of China(17B230);Planning Project of Hunan Provincial Health and Family Planning Commission Research Projects(C2016042);the Start-up Funds for Ph.D.s in University of South China(2015XQD27;2015XQD28);Applied Anatomy and Reproductive Medicine Key Laboratory Construction Project in Hengyang(2017KJ182);Graduate Student Research Innovation Project of University of South China in 2018(2018KYY256;2018KYY258;2018KYZ065;2018KYZ069)
- DOI：10.11889/j.1000-3436.2019.rrj.37.010301
  CLC： R818.74
- Received：03 September 2018，
  
  Revised：29 November 2018，
  
  Accepted：2018-11-29，
  
  Published：20 February 2019
- 稿件说明：
移动端阅览
王贞,罗诗诗,牛磊等.电离辐射激活海马星形胶质细胞诱导小鼠认知功能障碍[J].辐射研究与辐射工艺学报,2019,37(01):19-25.

WANG Zhen,LUO Shishi,NIU Lei,et al.Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice[J].Journal of Radiation Research and Radiation Processing,2019,37(01):19-25.
王贞,罗诗诗,牛磊等.电离辐射激活海马星形胶质细胞诱导小鼠认知功能障碍[J].辐射研究与辐射工艺学报,2019,37(01):19-25. DOI： 10.11889/j.1000-3436.2019.rrj.37.010301.

WANG Zhen,LUO Shishi,NIU Lei,et al.Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice[J].Journal of Radiation Research and Radiation Processing,2019,37(01):19-25. DOI： 10.11889/j.1000-3436.2019.rrj.37.010301.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Ionizing radiation induces cognitive dysfunction by activating prefrontal cortex NLRP3 inflammasome in mice

Environmental enrichment improves irradiation-induced cognitive dysfunction

Investigating the performance of polytetrafluoroethylene solid free radical dosimeter

Autophagy regulates ionizing radiation-induced primary ciliogenesis in glioblastoma cells

Preparation of hydrogel-based photocatalytic composite materials by radiation technology

Related Author

NAI Aitao

WANG Zhen

LUO Dan

WANG Yixuan

WAN Wei

CAO Wenyu

CHEN Xi

WANG Wuzhou

Related Institution

School of Basic Medicine, Xiangnan University

Shanghai JinPengYuan Irradiation Technology Co., Ltd.

Shanghai Institute of Applied Physics, Chinese Academy of Sciences

Department of Pathology, The 940th Hospital of Joint Logistics Support force of Chinese People’s Liberation Army

School of Life Sciences, Lanzhou University

⁰

Ionizing radiation induces cognitive dysfunction by activating hippocampal astrocytes in mice

DOI：10.11889/j.1000-3436.2019.rrj.37.010301