Progress in nanotechnology-based boron agents for BNCT

SHI Haojie; LI Fenglin; FAN Caiyun; XU Qianlong

doi:10.11889/j.1000-3436.2025-0102

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Progress in nanotechnology-based boron agents for BNCT

更新时间：2026-05-06

- Progress in nanotechnology-based boron agents for BNCT
- Journal of Radiation Research and Radiation Processing Pages: 1-14(2026)
- 作者机构：
  
  中国原子能科学研究院北京 102413
- 作者简介：
  
  SHI Haojie (male) was born in March 2001 and obtaind a bachelor's degree from Northeast Forestry University. Currently, he is a postgraduate student at the China Institute of Atomic Energy, majoring in Analytical Chemistry and specializing in radiopharmaceutical research, E-mail: 863593574@qq.com
  LI Fenglin, professor, master supurvisor, E-mail: 99789770@qq.com
- 基金信息：
  
  the Industrial Fund of China Institute of Atomic Energy(PG040270925876)
- DOI：10.11889/j.1000-3436.2025-0102
  CLC： R9
- Received：24 October 2025，
  
  Revised：2026-01-09，
  
  Accepted：09 January 2026，
  
  Online First：06 May 2026，
- 稿件说明：
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引用该文：史豪杰, 李凤林, 樊彩云, 等. 纳米粒子型硼携带剂用于硼中子俘获治疗的研究进展[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX.

SHI Haojie, LI Fenglin, FAN Caiyun, et al. Progress in nanotechnology-based boron agents for BNCT[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX.
引用该文：史豪杰, 李凤林, 樊彩云, 等. 纳米粒子型硼携带剂用于硼中子俘获治疗的研究进展[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0102. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0102.

SHI Haojie, LI Fenglin, FAN Caiyun, et al. Progress in nanotechnology-based boron agents for BNCT[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0102. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0102.

摘要

硼中子俘获治疗（Boron neutron capture therapy，BNCT）是一种基于二元靶向的肿瘤治疗方式，含硼药物在肿瘤特异性富集后，经热中子局部照射，通过

B（n，α）⁷Li核反应从而实现肿瘤的精准放疗。第二代硼携带剂硼苯丙氨酸（Boronophenylalanine，BPA）、巯基十二硼烷二钠盐（Sodium borocaptate，BSH）在肿瘤治疗中展现出良好的治疗效果，但也存在肿瘤靶向性不足、体内代谢快或溶解性差等问题，为应对以上挑战，基于纳米技术的纳米粒子型硼携带剂已成为能否增强BNCT治疗效果的关键之一。本文系统回顾了纳米粒子型硼携带剂的研究进展，同时对于目前纳米粒子型硼携带剂存在的不足进行分析并提出建议，以期为纳米粒子型硼携带剂在基础和临床研究应用中的发展提供一定帮助。

Abstract

Boron neutron capture therapy (BNCT) is a two-step targeted radiotherapy technique. It involves the selective delivery of boron agents to tumor tissues

followed by thermal neutron irradiation. The subsequent

B(n

α)⁷Li nuclear reaction results in selective destruction of tumor

cells. The second-generation boron agents

boronophenylalanine (BPA) and sodium borocaptate (BSH)

have demonstrated promising results in tumor treatment. However

they still face several challenges

such as insufficient tumor targeting

rapid metabolism or poor solubility. In order to meet the above challenges

nanotechnology-based boron agents have become a key strategy to enhance the therapeutic effect of BNCT. In this article

we systematically review the research progress of nanotechnology-based boron agents

and at the same time

critically analyze the shortcomings of current nanocarriers and propose potential solutions

with the aim of facilitating the translation of nanotechnology-based boron agents into both basic research and clinical applications.

关键词

Keywords

references

李纪元 , 涂智宇 , 刘志博 . 走进曙色的冷门方向: 硼携带剂发展历程简述 [J ] . 中国科学: 化学 , 2020 , 50 ( 10 ): 1296 - 1319 . DOI: 10.1360/SSC-2020-0114 http://dx.doi.org/10.1360/SSC-2020-0114 .

LI Jiyuan , TU Zhiyu , LIU Zhibo . Development history of boron delivery agents [J ] . Scientia Sinica Chimica , 2020 , 50 ( 10 ): 1296 - 1319 . DOI: 10.1360/SSC-2020-0114 http://dx.doi.org/10.1360/SSC-2020-0114 .

李凤林 , 罗志福 . 用于硼中子俘获治疗的硼携带剂研究现状 [J ] . 科学通报 , 2022 , 67 ( 14 ): 1517 - 1531 . DOI: 10.1360/TB-2021-1013 http://dx.doi.org/10.1360/TB-2021-1013 .

LI Fenglin , LUO Zhifu . Boron delivery agents for boron neutron capture therapy [J ] . Chinese Science Bulletin , 2022 , 67 ( 14 ): 1517 - 1531 . DOI: 10.1360/TB-2021-1013 http://dx.doi.org/10.1360/TB-2021-1013 .

Li J Y , Sun Q , Lu C J , et al . Boron encapsulated in a liposome can be used for combinational neutron capture therapy [J ] . Nature Communications , 2022 , 13 : 2143 . DOI: 10.1038/s41467-022-29780-w http://dx.doi.org/10.1038/s41467-022-29780-w .

Chen J J , Dai Q , Yang Q Y , et al . Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma [J ] . Journal of Nanobiotechnology , 2022 , 20 ( 1 ): 102 . DOI: 10.1186/s12951-022-01304-0 http://dx.doi.org/10.1186/s12951-022-01304-0 .

Yanagië H , Ogura K , Takagi K , et al . Suppression of tumor growth in a rabbit hepatic cancer model by boron neutron capture therapy with liposomal boron delivery systems [J ] . Applied radiation and isotopes , 2004 , 61 ( 4 ): 639 - 46 . DOI: 10.21873/invivo.12607 http://dx.doi.org/10.21873/invivo.12607 .

Singh A , Kim B K , Mackeyev Y , et al . Boron-nanoparticle-loaded folic-acid-functionalized liposomes to achieve optimum boron concentration for boron neutron capture therapy of cancer [J ] . Journal of Biomedical Nanotechnology , 2019 , 15 ( 8 ): 1714 - 1723 . DOI: 10.1166/jbn.2019.2800 http://dx.doi.org/10.1166/jbn.2019.2800 .

Feng B , Tomizawa K , Michiue H , et al . Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His [J ] . Biomaterials , 2009 , 30 ( 9 ): 1746 - 1755 . DOI: 10.1016/j.biomaterials.2008.12.010 http://dx.doi.org/10.1016/j.biomaterials.2008.12.010 .

Qin Y X , Sun X Y , Zhang Z C , et al . Dual-functional nanoliposome with high BPA loading for targeted MRI-guided BNCT of glioblastoma [J ] . ACS Applied Materials & Interfaces , 2025 , 17 ( 37 ): 52474 - 52487 . DOI: 10.1021/acsami.5c11509 http://dx.doi.org/10.1021/acsami.5c11509 .

Kawasaki R , Oshige A , Yamana K , et al . HER-2-targeted boron neutron capture therapy with carborane-integrated immunoliposomes prepared via an exchanging reaction [J ] . Chemistry – A European Journal , 2023 , 29 ( 72 ): e202302486 . DOI: 10.1002/chem.202302486 http://dx.doi.org/10.1002/chem.202302486 .

Chan J M , Valencia P M , Zhang L F , et al . Polymeric nanoparticles for drug delivery [M ] // Cancer Nanotechnology . Totowa, NJ : Humana Press , 2010 : 163 - 175 . DOI: 10.1007/978-1-60761-609-2_11 http://dx.doi.org/10.1007/978-1-60761-609-2_11 .

Elsabahy M , Wooley K L . Design of polymeric nanoparticles for biomedical delivery applications [J ] . Chemical Society Reviews , 2012 , 41 ( 7 ): 2545 - 2561 . DOI: 10.1039/c2cs15327k http://dx.doi.org/10.1039/c2cs15327k .

Mi P , Yanagie H , Dewi N , et al . Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors [J ] . Journal of Controlled Release , 2017 , 254 : 1 - 9 . DOI: 10.1016/j.jconrel.2017.03.036 http://dx.doi.org/10.1016/j.jconrel.2017.03.036 .

Xiong H J , Zhou D F , Qi Y X , et al . Doxorubicin-loaded carborane-conjugated polymeric nanoparticles as delivery system for combination cancer therapy [J ] . Biomacromolecules , 2015 , 16 ( 12 ): 3980 - 3988 . DOI: 10.1021/acs.biomac.5b01311 http://dx.doi.org/10.1021/acs.biomac.5b01311 .

Takeuchi I , Nomura K , Makino K . Hydrophobic boron compound-loaded poly(l-lactide-co-glycolide) nanoparticles for boron neutron capture therapy [J ] . Colloids and Surfaces B: Biointerfaces , 2017 , 159 : 360 - 365 . DOI: 10.1016/j.colsurfb.2017.08.002 http://dx.doi.org/10.1016/j.colsurfb.2017.08.002 .

Dai L Q , Wang T , Zhou S M , et al . Boronophenylalanine-containing polydopamine nanoparticles for enhanced combined boron neutron capture therapy and photothermal therapy for melanoma treatment [J ] . Advanced Functional Materials , 2024 , 34 ( 38 ): 2402893 . DOI: 10.1002/adfm.202402893 http://dx.doi.org/10.1002/adfm.202402893 .

Ruan Z , Liu L , Fu L Y , et al . An amphiphilic block copolymer conjugated with carborane and a NIR fluorescent probe for potential imaging-guided BNCT therapy [J ] . Polymer Chemistry , 2016 , 7 ( 26 ): 4411 - 4418 . DOI: 10.1039/C6PY00799F http://dx.doi.org/10.1039/C6PY00799F .

Shi Y X , Li J Y , Zhang Z Z , et al . Tracing boron with fluorescence and positron emission tomography imaging of boronated porphyrin nano complex for imaging-guided boron neutron capture therapy [J ] . ACS Applied Materials & Interfaces , 2018 , 10 ( 50 ): 43387 - 43395 . DOI: 10.1021/acsami.8b14682 http://dx.doi.org/10.1021/acsami.8b14682 .

Zhang T F , Li G , Li S R , et al . Asialoglycoprotein receptor targeted micelles containing carborane clusters for effective boron neutron capture therapy of hepatocellular carcinoma [J ] . Colloids and Surfaces B: Biointerfaces , 2019 , 182 : 110397 . DOI: 10.1016/j.colsurfb.2019.110397 http://dx.doi.org/10.1016/j.colsurfb.2019.110397 .

Gao Z Y , Horiguchi Y , Nakai K , et al . Use of boron cluster-containing redox nanoparticles with ROS scavenging ability in boron neutron capture therapy to achieve high therapeutic efficiency and low adverse effects [J ] . Biomaterials , 2016 , 104 : 201 - 212 . DOI: 10.1016/j.biomaterials.2016.06.046 http://dx.doi.org/10.1016/j.biomaterials.2016.06.046 .

Lisha V S , Mayilswamy N , Kandasubramanian B . Molecular dynamics simulation of PAMAM dendrimer-drug delivery systems [J ] . Biomedical Materials & Devices , 2025 , 3 ( 2 ): 1220 - 1227 . DOI: 10.1007/s44174-024-00229-6 http://dx.doi.org/10.1007/s44174-024-00229-6 .

Tupally K R , Seal P , Pandey P , et al . Integration of dendrimer-based delivery technologies with computational pharmaceutics and their potential in the era of nanomedicine [J ] . Exploring Computational Pharmaceutics‐AI and Modeling in Pharma 4.0 , 2024 : 328 - 378 . DOI: 10.1002/9781119987260.ch10 http://dx.doi.org/10.1002/9781119987260.ch10 .

Patle R Y , Dongre R S . Recent advances in PAMAM mediated nano-vehicles for targeted drug delivery in cancer therapy [J ] . Journal of Drug Targeting , 2025 , 33 ( 4 ): 437 - 457 . DOI: 10.1080/1061186x.2024.2428966 http://dx.doi.org/10.1080/1061186x.2024.2428966 .

Ahmed R , Aucamp M , Ebrahim N , et al . Supramolecular assembly of rifampicin and PEGylated PAMAM dendrimer as a novel conjugate for tuberculosis [J ] . Journal of Drug Delivery Science and Technology , 2021 , 66 : 102773 . DOI: 10.1016/j.jddst.2021.102773 http://dx.doi.org/10.1016/j.jddst.2021.102773 .

Lai C H , Lin Y C , Chou F I , et al . Design of multivalent galactosyl carborane as a targeting specific agent for potential application to boron neutron capture therapy [J ] . Chemical Communications , 2012 , 48 ( 4 ): 612 - 614 . 10.1039/c1cc14447b http://dx.doi.org/10.1039/c1cc14447b

Lai C H , Lai N C , Chuang Y J , et al . Trivalent galactosyl-functionalized mesoporous silica nanoparticles as a target-specific delivery system for boron neutron capture therapy [J ] . Nanoscale , 2013 , 5 ( 19 ): 9412 - 9418 . 10.1039/c3nr02594b http://dx.doi.org/10.1039/c3nr02594b

Wu G , Barth R F , Yang W L , et al . Site-specific conjugation of boron-containing dendrimers to anti-EGF receptor monoclonal antibody cetuximab (IMC-C225) and its evaluation as a potential delivery agent for neutron capture therapy [J ] . Bioconjugate Chemistry , 2004 , 15 ( 1 ): 185 - 194 . DOI: 10.1021/bc0341674 http://dx.doi.org/10.1021/bc0341674 .

Tsuji T , Yoshitomi H , Ishikawa Y , et al . A method to selectively internalise submicrometer boron carbide particles into cancer cells using surface transferrin conjugation for developing a new boron neutron capture therapy agent [J ] . Journal of Experimental Nanoscience , 2020 , 15 ( 1 ): 1 - 11 . DOI: 10.1080/17458080.2019. 1692178 http://dx.doi.org/10.1080/17458080.2019.1692178 .

Kaur M , Singh P , Meena R , et al . Boron neutron capture therapy study of 10 B enriched nanostructured boron carbide against cervical cancer and glioblastoma cell line [J ] . Journal of Cluster Science , 2021 , 32 ( 1 ): 221 - 225 . DOI: 10.1007/s10876-020-01773-z http://dx.doi.org/10.1007/s10876-020-01773-z .

Li L P , Li J Y , Shi Y X , et al . On-demand biodegradable boron nitride nanoparticles for treating triple negative breast cancer with boron neutron capture therapy [J ] . ACS Nano , 2019 , 13 ( 12 ): 13843 - 13852 . DOI: 10.1021/acsnano.9b04303 http://dx.doi.org/10.1021/acsnano.9b04303 .

Zhang Y C , Kang H G , Xu H Z , et al . Tumor eradication by boron neutron capture therapy with 10 B-enriched hexagonal boron nitride nanoparticles grafted with poly(glycerol) [J ] . Advanced Materials , 2023 , 35 ( 35 ): 2301479 . DOI: 10.1002/adma.202301479 http://dx.doi.org/10.1002/adma.202301479 .

Nakamura H , Koganei H , Miyoshi T , et al . Antitumor effect of boron nitride nanotubes in combination with thermal neutron irradiation on BNCT [J ] . Bioorganic & Medicinal Chemistry Letters , 2015 , 25 ( 2 ): 172 - 174 . DOI: 10.1016/j.bmcl.2014.12.005 http://dx.doi.org/10.1016/j.bmcl.2014.12.005 .

Li W , Cao Z W , Liu R , et al . AuNPs as an important inorganic nanoparticle applied in drug carrier systems [J ] . Artificial Cells, Nanomedicine, and Biotechnology , 2019 , 47 ( 1 ): 4222 - 4233 . DOI: 10.1080/21691401.2019. 1687501 http://dx.doi.org/10.1080/21691401.2019.1687501 .

Chandrakala V , Aruna V , Angajala G . Review on metal nanoparticles as nanocarriers: current challenges and perspectives in drug delivery systems [J ] . Emergent Materials , 2022 , 5 ( 6 ): 1593 - 1615 . DOI: 10.1007/s42247-021-00335-x http://dx.doi.org/10.1007/s42247-021-00335-x .

Rosyidah A , Kerdtoob S , Yudhistyra W I , et al . Gold nanoparticle-based drug nanocarriers as a targeted drug delivery system platform for cancer therapeutics: a systematic review [J ] . Gold Bulletin , 2023 , 56 ( 3 ): 121 - 134 . DOI: 10.1007/s13404-023-00331-5 http://dx.doi.org/10.1007/s13404-023-00331-5 .

Kubota T , Kuroda S , Kanaya N , et al . HER2-targeted gold nanoparticles potentially overcome resistance to trastuzumab in gastric cancer [J ] . Nanomedicine: Nanotechnology, Biology and Medicine , 2018 , 14 ( 6 ): 1919 - 1929 . DOI: 10.1016/j.nano.2018.05.019 http://dx.doi.org/10.1016/j.nano.2018.05.019 .

Li N , Zhao P X , Salmon L , et al . “Click” star-shaped and dendritic PEGylated gold nanoparticle-carborane assemblies [J ] . Inorganic Chemistry , 2013 , 52 ( 19 ): 11146 - 11155 . DOI: 10.1021/ic4013697 http://dx.doi.org/10.1021/ic4013697 .

Ciani L , Bortolussi S , Postuma I , et al . Rational design of gold nanoparticles functionalized with carboranes for application in boron neutron capture therapy [J ] . International Journal of Pharmaceutics , 2013 , 458 ( 2 ): 340 - 346 . DOI: 10.1016/j.ijpharm.2013.10.008 http://dx.doi.org/10.1016/j.ijpharm.2013.10.008 .

Pulagam K R , Gona K B , Gómez-Vallejo V , et al . Gold nanoparticles as boron carriers for boron neutron capture therapy: synthesis, radiolabelling and in vivo evaluation [J ] . Molecules , 2019 , 24 ( 19 ): 3609 . DOI: 10.3390/molecules24193609 http://dx.doi.org/10.3390/molecules24193609 .

Wu C Y , Lin J J , Chang W Y , et al . Development of theranostic active-targeting boron-containing gold nanoparticles for boron neutron capture therapy (BNCT) [J ] . Colloids and Surfaces B: Biointerfaces , 2019 , 183 : 110387 . DOI: 10.1016/j.colsurfb.2019.110387 http://dx.doi.org/10.1016/j.colsurfb.2019.110387 .

Dai C X , Cai F , Hwang K C , et al . Folate receptor-mediated boron-10 containing carbon nanoparticles as potential delivery vehicles for boron neutron capture therapy of nonfunctional pituitary adenomas [J ] . Science China Life Sciences , 2013 , 56 ( 2 ): 163 - 173 . DOI: 10.1007/s11427-012-4433-5 http://dx.doi.org/10.1007/s11427-012-4433-5 .

Yamagami M , Tajima T , Ishimoto K , et al . Physical modification of carbon nanotubes with a dendrimer bearing terminal mercaptoundecahydrododecaborates (Na 2 B 12 H 11 S) [J ] . Heteroatom Chemistry , 2018 , 29 ( 5/6 ): e21467 . DOI: 10.1002/hc.21467 http://dx.doi.org/10.1002/hc.21467 .

Lin B R , Kunuku S , Chen T Y , et al . Fluorescent 10B embedded nanodiamonds as 10B delivery agent for boron neutron capture therapy [J ] . Journal of Physics D: Applied Physics , 2019 , 52 ( 26 ): 26LT01 . DOI: 10.1088/1361-6463/ab188c http://dx.doi.org/10.1088/1361-6463/ab188c .

Zhu Y H , Lin Y X , Zhu Y Z , et al . Boron drug delivery via encapsulated magnetic nanocomposites: a new approach for BNCT in cancer treatment [J ] . Journal of Nanomaterials , 2010 , 2010 : 409320 . DOI: 10.1155/2010/409320 http://dx.doi.org/10.1155/2010/409320 .

Tulebayeva D Z , Kozlovskiy A L , Korolkov I V , et al . Modification of Fe 3 O 4 nanoparticles with carboranes [J ] . Materials Research Express , 2018 , 5 ( 10 ): 105011 . DOI: 10.1088/2053-1591/aadb08 http://dx.doi.org/10.1088/2053-1591/aadb08 .

Oleshkevich E , Morancho A , Saha A , et al . Combining magnetic nanoparticles and icosahedral boron clusters in biocompatible inorganic nanohybrids for cancer therapy [J ] . Nanomedicine: Nanotechnology, Biology and Medicine , 2019 , 20 : 101986 . DOI: 10.1016/j.nano.2019. 03.008 http://dx.doi.org/10.1016/j.nano.2019.03.008 .

Fujii H , Matsuyama A , Komoda H , et al . Cationized gelatin-HVJ envelope with sodium borocaptate improved the BNCT efficacy for liver tumors in vivo [J ] . Radiation Oncology , 2011 , 6 ( 1 ): 8 . DOI: 10.1186/1748-717X-6-8 http://dx.doi.org/10.1186/1748-717X-6-8 .

Yoneoka S , Nakagawa Y , Uto K , et al . Boron-incorporating hemagglutinating virus of Japan envelope (HVJ-E) nanomaterial in boron neutron capture therapy [J ] . Science and Technology of Advanced Materials , 2019 , 20 ( 1 ): 291 - 304 . DOI: 10.1080/14686996.2019. 1586051 http://dx.doi.org/10.1080/14686996.2019.1586051 .

南京工业大学 . 一种表面修饰碳硼烷的介孔二氧化硅纳米球及其制备方法 : CN110302381B [P ] . 2021-12-03 .

Nanjing Tech University . Mesoporous silica nanosphere with carborane modified on surface and preparation method thereof : CN110302381B [P ] . 2021-12-03 .

兰州大学 . 肝癌靶向性负载碳硼烷中空介孔二氧化硅的制备及其在肝癌硼中子俘获治疗药物中的应用 : CN114984247A [P ] . 2022-09-02 .

Lanzhou University . Preparation of liver cancer targeting carborane loaded hollow mesoporous silica and application of silica in boron neutron capture treatment medicine for liver cancer : CN114984247A [P ] . 2022-09-02 .

Tang H Y , Wang Z J , Hao H Y , et al . Boron-containing mesoporous silica nanoparticles with effective delivery and targeting of liver cancer cells for boron neutron capture therapy [J ] . ACS Applied Materials & Interfaces , 2024 , 16 ( 18 ): 22934 - 22945 . DOI: 10.1021/acsami.4c02897 http://dx.doi.org/10.1021/acsami.4c02897 .

Wang Z J , Chen Z T , Zhang Z Z , et al . Multifunctional high boron content MOFs nano-co-crystals for precise boron neutron capture therapy for brain glioma in situ [J ] . Nano Today , 2022 , 45 : 101558 . DOI: 10.1016/j.nantod. 2022.101558 http://dx.doi.org/10.1016/j.nantod.2022.101558 .

Wang Z J , Lei R H , Zhang Z Z , et al . Boron-containing MOF nanoparticles with stable metabolism in U87-MG cells combining microdosimetry to evaluate relative biological effectiveness of boron neutron capture therapy [J ] . ACS Applied Materials & Interfaces , 2024 , 16 ( 3 ): 3232 - 3242 . DOI: 10.1021/acsami.3c19113 http://dx.doi.org/10.1021/acsami.3c19113 .

Dai L Q , Liu J , Yang T Y , et al . Lipoic acid-boronophenylalanine-derived multifunctional vesicles for cancer chemoradiotherapy [J ] . Nature Communications , 2025 , 16 ( 1 ): 1329 . DOI: 10.1038/s41467-025-56507-4 http://dx.doi.org/10.1038/s41467-025-56507-4 .

郝昕 , 谭志新 , 童永彭 , 等 . 硼中子俘获技术对普通小球藻生长的影响 [J ] . 辐射研究与辐射工艺学报 , 2014 , 32 ( 6 ): 060401 . DOI: 10.11889/j.1000-3436.2014.rrj.32. 060401 http://dx.doi.org/10.11889/j.1000-3436.2014.rrj.32.060401 .

HAO Xin , TAN Zhixin , TONG Yongpeng , et al . Effects of boron neutron capture on growth of Chlorella vulgaris [J ] . Journal of Radiation Research and Radiation Processing , 2014 , 32 ( 6 ): 060401 . DOI: 10.11889/j.1000-3436.2014.rrj.32.060401 http://dx.doi.org/10.11889/j.1000-3436.2014.rrj.32.060401 .

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