Research progress on the effects of ionizing radiation on epigenetic modification

TANG Mingwei; ZHANG Dandan; SUN Peilin; SIQIN Tuya; ZHANG Zicheng; TENG Weili

doi:10.11889/j.1000-3436.2025-0108

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Research progress on the effects of ionizing radiation on epigenetic modification

更新时间：2026-04-29

- Research progress on the effects of ionizing radiation on epigenetic modification
- Journal of Radiation Research and Radiation Processing Pages: 1-14(2026)
- 作者机构：
  
  1.黑龙江省原子能研究院哈尔滨 150086
  2.东北农业大学农学院哈尔滨 150006
- 作者简介：
  
  TANG Mingwei (female) was born in 1993, and obtained a doctoral degree from Northeast Forestry University in 2023, mainly engaged in research on radiation biological effect of plant
  TENG Weili, professor, E-mail: twlneau@163.com
- 基金信息：
  
  National Natural Science Foundation of Heilongjiang Province(PL2025A020);Research Project for Scientific Research Foundation of Provincial Research Institutions of Heilongjiang Province(CZKYF2025-1-C070);The Soybean Breeding Research Project of the Department of Agriculture and Rural Affairs of Heilongjiang Province, and Youth Innovation Foundation of Heilongjiang Academy of Sciences(RC2026YZN02)
- DOI：10.11889/j.1000-3436.2025-0108
  CLC： Q691.5
- Received：08 December 2025，
  
  Revised：2026-04-02，
  
  Accepted：02 April 2026，
  
  Online First：29 April 2026，
- 稿件说明：
移动端阅览
汤明威, 张丹丹, 孙培琳, 等. 电离辐射对表观遗传修饰影响的研究进展[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX.

TANG Mingwei, ZHANG Dandan, SIQIN Tuya, et al. Research progress on the effects of ionizing radiation on epigenetic modification[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX.
汤明威, 张丹丹, 孙培琳, 等. 电离辐射对表观遗传修饰影响的研究进展[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0108. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0108.

TANG Mingwei, ZHANG Dandan, SIQIN Tuya, et al. Research progress on the effects of ionizing radiation on epigenetic modification[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0108. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0108.

摘要

电离辐射作为一种重要的胁迫手段，能够对生物体造成损伤，其对生物体造成DNA损伤的机制已得到较为明确的解析。随着研究深入，电离辐射的生物效应研究已从经典的DNA损伤与修复机制，逐步拓展至表观遗传学这一新兴前沿领域。本文系统地综述了电离辐射对植物表观遗传修饰影响的研究进展，重点探讨了DNA甲基化、组蛋白修饰、非编码RNA及RNA甲基化等表观遗传机制在辐射胁迫下的动态变化及其生物学意义。为理解辐射表观遗传效应提供了理论基础，并对辐射防护、癌症治疗与作物育种等领域具有重要参考价值。

Abstract

Ionizing radiation serves as a significant stressor capable of inflicting damage on organisms

and the mechanisms underlying its DNA-damaging effects have been increasingly elucidated. As research has advanced

the investigation of the biological effects of ionizing radiation has progressively shifted from traditional mechanisms of DNA damage and repair to the emerging field of epigenetics. This paper systematically reviews the progress in understanding the effects of ionizing radiation on epigenetic modifications in plants

emphasizing the dynamic alterations in epigenetic mechanisms

including DNA methylation

histone modification

non-coding RNA

and RNA methylation in response to radiation stress

as well as their biological significance. This review provides a theoretical foundation for comprehending the epigenetic effects of radiation and holds substantial reference value in the domains of radiation protection

cancer treatment

and crop breeding.

关键词

Keywords

references

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