Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice

ZHANG Haoran; LIU Jun; ZHANG Zhongwei; XUE Wei; WANG Mimi; LIU Qingjie

doi:10.11889/j.1000-3436.2025-0111

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Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice

更新时间：2026-01-13

- Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice
- “The latest research has found that the Mmp family plays an important role in the process of intestinal injury and repair caused by gamma rays, and key genes such as Mmp8 may become therapeutic targets.”
- Journal of Radiation Research and Radiation Processing Pages: 1-10(2026)
- 作者机构：
  
  中国疾病预防控制中心辐射防护与核安全医学所辐射防护与核应急中国疾病预防控制中心重点实验室北京 100088
- 作者简介：
  
  ZHANG Haoran (male) was born in September 2002, graduated from Central South University in July 2024, majoring in bioinformatics. Now he is a graduate student in radiation medicine at National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, E-mail: zhanghaoran020903@163.com
  LIU Qingjie, doctoral degree, researcher, E-mail: liuqingjie@nirp.chinacdc.cn
- 基金信息：
  
  National Natural Science Foundation of China(82173463)
- DOI：10.11889/j.1000-3436.2025-0111
  CLC： Q691;R818.7
- Received：26 November 2025，
  
  Revised：2025-12-26，
  
  Accepted：26 December 2025，
  
  Published Online：13 January 2026，
- 稿件说明：
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引用该文：张浩然, 刘俊, 张中伟, 等. 伽马射线照射对小鼠肠道干细胞及分化细胞关键基因的影响及鉴定[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX.

ZHANG Haoran, LIU Jun, ZHANG Zhongwei, et al. Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX.
引用该文：张浩然, 刘俊, 张中伟, 等. 伽马射线照射对小鼠肠道干细胞及分化细胞关键基因的影响及鉴定[J]. 辐射研究与辐射工艺学报, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0111. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0111.

ZHANG Haoran, LIU Jun, ZHANG Zhongwei, et al. Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice[J]. Journal of Radiation Research and Radiation Processing, XXXX, XX(XX): XXXXXX. DOI： 10.11889/j.1000-3436.2025-0111. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0111.

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Effects and identification of gamma irradiation on key genes of intestinal stem cells and differentiated cells in mice

DOI：10.11889/j.1000-3436.2025-0111