最新刊期
      期 1 ， 2008
      • LI Yuwen,LIU Qingjie
        Vol. 26, Issue 1, Pages: 1-4(2008)
        摘要：As the non-code region of mitochondrial genome, the displacement-loop region (D-loop) controls the replication and transcription of mtDNA, but it is easy to be altered. The variation, including mutation and polymorphism, plays an important role in disease. Finally, the status quo of radiation induced D-loop variation and its perspective were outlined.  
        关键词：Mitochondrial D-loop;Mutation;Polymorphism;Irradiation   
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        发布时间：2023-03-30
      • WANG Jianhua,QIU Xiaoping,LUO Zhiping,XU Xunjiang,HUA Zhengdong
        Vol. 26, Issue 1, Pages: 5-8(2008)
        摘要：This work is dedicated to design the dose field uniformity of irradiation facility installed 576 cobalt sources sticks by use of Monte Carlo method and MATLAB language. By comparing calculations with measurements the further calculation of dose distribution in the irradiation facility was performed by setting 3200 tally points of irradiation doses. In order to obtain the optimum data employed in our study, numerous position adjustments of the cobalt source sticks were made to calculate the dose distribution of the irradiation facility. And it had been found that there was a good agreement between program calculations and the measurements. The dose uniformity of irradiation facility and the efficiency of energy usage will be greatly increased after adjusting the cobalt source sticks according to the calculated results.  
        关键词：Cobalt source;Irradiation facility;Program calculation;Dose uniformity   
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        发布时间：2023-03-30
      • LIU Ruiqin,YAO Side,XIE Leidong,SHENG Kanglong
        Vol. 26, Issue 1, Pages: 9-12(2008)
        摘要：In order to explore the possibility of modifying the surface of silk fabrics with graft process by use of UV light irradiation, Electron-spin resonance (ESR) studies were carried out to detect the radicals induced on the surface of silk fabrics exposed to three kinds of UV light sources at room temperature. And similar ESR signals were observed. The results indicate that UV-rays can produce free radicals on the surface of silk fibers without external additives or co-additives and oxygen might affect the radical spectra and concentration. From the analysis of ESR spectra, it is found that UV-light may be a tool to improve the surface properties of silk fabrics by grafting monomers onto the silk polymer chains.  
        关键词：Electron-spin resonance (ESR);Silk;Free radical;UV-ray induced graft-copolymeriazation   
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        发布时间：2023-03-30
      • ZHAO Jun,WANG Min,MA Hongjuan,YAO Side,YANG Ruiyuan,SHEN Zhongqun,PU Changyong,ZHANG Jing
        Vol. 26, Issue 1, Pages: 13-18(2008)
        摘要：Degradation of alizarin S in aqueous solutions was studied by use of 60Co γ-rays. Changes of absorption spectra, degree of decoloriation and total organic carbon (TOC) removal were investigated by changing the absorbed doses, primary concentration of alizarin S, the pH of the system, added amounts of H2O2 and saturated with different gases in system, Results show that decoloriation and TOC removal efficiency is of 98 % and about 70 % respectively when the added concentration of H2O2 was 4mmol/L and aqueous solution was saturated with air at 7.5kGy irradiation. The results suggested that the radiation technology might be a promising process for treatment of textile dye waste effluents.  
        关键词：Radiation;Degradation;Alizarin S;Decoloriation;Total organic carbon (TOC)   
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        发布时间：2023-03-30
      • BAO Mao,JIAO Yang,KANG Xingchuan,LU Yongjun,LI Shufeng,ZENG Xinmiao
        Vol. 26, Issue 1, Pages: 19-22(2008)
        摘要：Natural rubber(NR)/styrene butadiene rubber(SBR) blends was precured by electron beams(EB) irradiation. The crosslinking degree、green strength and heat curing speed of NR/SBR were studied with different absorbed doses. And the effects of EB irradiation precuring on the final mechanical properties were evaluated. The results show that the crosslinking degree and green strength of NR/SBR was improved respectively while the heat curing speed was not changed with increasing absorbed doses. The final mechanical properties were not significantly changed between the irradiation precuring and non-irradiation precuring of NR/SBR. The EB irradiation precuring of NR/SBR may be suitable for rubber process.  
        关键词：Natural rubber(NR)/styrene butadiene rubber(SBR);Electron beam(EB);Irradiation precuring;Absorbed dose;Green strength   
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        发布时间：2023-03-30
      • HUANG Haitao,WANG Dan,ZHOU Lijuan,ZHAO Xue
        Vol. 26, Issue 1, Pages: 23-27(2008)
        摘要：The adventitious buds of orential lily "Sorbonne" were treated with 60Co γ-rays at doses of 0, 0.5, 1.0, 2.0, 4.0, 6.0 and 8.0Gy respectively. Effects of 60Co γ-rays irradiation at different doses on growth and physiological characteristics of adventitious bud of oriental lily have been studied. With the increase of irradiation dose, MDA content and plasmalemma permeability in adventitious bud of oriental lily increases. Superoxide anion (O2-) content and catalase (CAT) activity in adventitious bud of oriental lilies which are treated at doses of 2.0, 4.0, 6.0 and 8.0Gy is higher than that in the control group, and germination rates are less than that of the control group. The increment of height of buds which are treated at doses of 4.0, 6.0 and 8.0Gy respectively is less than that of the control group. The results show that 60Co γ-rays irradiation has the inhibiting effect on the growth of adventitious bud of oriental lily. It can be concluded that the optimum irradiation dose range is from 2.0Gy to 4.0Gy, and LD50 range is from 4.0Gy to 6.0Gy.  
        关键词：60Co γ-rays;Oriental lily;Irradiation;Adventitious bud;Growth   
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        发布时间：2023-03-30
      • WANG Zhicheng,LI Yanbo,GONG Pingsheng,LIU Shuchun,LIU Yang,KANG Shunai,ZHAO Gang,GONG Shouliang
        Vol. 26, Issue 1, Pages: 28-32(2008)
        摘要：In order to investigate the effects of low dose irradiation on the expression of apoptosis inducing factors (AIF) protein and its mRNA in spermatogenic cells of mouse testis, immunohisto-chemical technique (SABC) and RT-PCR was used to observe the change of AIF protein and its mRNA expressions in the spermatogenic cells of the mouse testis irradiated with X-rays at different absorbed doses. After irradiation with 0~0.2Gy, the AIF protein expression occurred principally in spermatogonia and spermatocytes and less in spermatids and spermazoa. It was found that the AIF protein expressions increased with irradiation doses and reached the highest at absorbed dose of 0.075Gy, and then decreased gradually along with increasing doses. It was also found that the expression increased with the expression time and reached its top at 12h after irradiation, and then it decreased gradually but was higher than that of at 0h. In the RT-PCR, it was observed that the largest mRNA expressions occurred at 0.1Gy while irradiation doses changed from 0 to 0.2Gy and the peak of AIF mRNA expressions was at 24h after irradiation with 0.075Gy. As a conclusion, the expressions of AIF protein and its mRNA in spermatogenic cells of mouse testis induced by low-dose irradiation have some relationship with absorbed doses and expression time after irradiation with X-rays.  
        关键词：Apoptosis inducing factors (AIF);mRNA;Irradiation;Testis;Spermatogenic cell   
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        发布时间：2023-03-30
      • ZHOU Qingming,ZHANG Hong,LIU Yang,ZHAO Weiping,LONG Jing,LI Ning,WANG Yanling
        Vol. 26, Issue 1, Pages: 39-42(2008)
        摘要：In order to investigate the effect of irradiation with 12C6+ ions on the space memory of the Kunming mouse, the mouse brain was irradiated with 12C6+ ions at low doses of 0, 0.5, 1 and 2.0Gy respectively. It was shown that the speed of looking for baits decreased with irradiation doses and then increased with the increment of the training times while the 8-arms radial maze was tested for determination of space memory. And the speed of looking for baits in irradiated and then trained groups recovered to the control level at 17th day after irradiation. It was also found that the space memory of the mice decreased along with the irradiation dose, but recovered to the control level at 20th day after irradiation. The data suggested that the irradiation of 0~2Gy 12C6+ ions affected the mouse space memory in a short period of time, and then it could be recovered with time gradually after the irradiation by training.  
        关键词：12C6+ ions radiation;Mouse;Space memory   
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        发布时间：2023-03-30
      • ZHANG Zhidong,MAO Jun,WANG Wei,TANG Qiyong,SHI Yuhu
        Vol. 26, Issue 1, Pages: 43-46(2008)
        摘要：A novel radio-resistant strain named RL2 was studied polyphasically, which was isolated from the soils in the Gurban-Tunggut Desert, Xinjiang. The strain is Gam-positive, sphere-shaped and pink pigmented; The DNA (G+C) contents of RL2 is 71.62mol%; The 16S rDNA genes of RL2 and D.radiodurans type strain DSM20539 shows a high level of similarity (97.2%). According to phenotypic characteristics and phylogenetic analysis, it can be suggested that the strain RL2 has been identified as Deinococcus.sp and it may be a novel species.  
        关键词：Radio-resistant strain;Isolated;Identify   
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        发布时间：2023-03-30
      • JIANG Yaqi,CHEN Ying,MU Rui,LIU Xiulin,LIU Fenju
        Vol. 26, Issue 1, Pages: 47-51(2008)
        摘要：To estimate exactly the biological dose of persons exposed to different dose rate, human peripheral blood was exposed to 60Co γ-rays in vitro at low, middle and high dose rates respectively and chromosome samples were prepared, then dose-response curves were established according to the dicentrics and ring frequencies. The result showed that the aberration frequency at same dose level increased with dose rate and there was an obvious dose-rate effect. Absorbed dose estimated with low dose-rate dose-response curve was higher markedly than that with high dose-rate dose-response curve. So, considering the effect of dose-rate, approximate dose-rate dose-response curve should be chosen when absorbed dose estimation and the result will be credible.  
        关键词：Radiation;Chromosome aberration;Dose-rate effect   
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        发布时间：2023-03-30
      • SUN Zhiqiang,LIU Fenju,CHEN Qiu,YANG Xueqin,FAN Saijun
        Vol. 26, Issue 1, Pages: 52-56(2008)
        摘要：In order to understand the radiosensitizing effects on human glioma cells SHG44 using celecoxib, a cyclooxygenase (COX)-2 selective inhibitor, MTT assay was used to determine the effect of celecoxib on the cell growth, and Colony Formation assay. Reverse transcription-PCR assay were used to investigate the effect of celecoxib or combined with 60Co γ-irradiation on cell colony formation rate and the levels of COX-2 mRNA expresstion .Experimental results suggested that the cytotoxicity of celecoxib enhanced along with the increment of drug's concentration. The celecoxib could inhibit colony formation in SHG44 cells. When combined with 60Co γ-irradiation, COX-2 mRNA expresstion levels was lower than that of control, drug and irradiation group respectively. The study confirmed the radiosensitizing effects of this drug to human glioma cells SHG44, and it might be closely related to the COX-2 mRNA expresstion levels.  
        关键词：Cancer;Celecoxib;Glioma;Radiosensitivity   
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        发布时间：2023-03-30
      • LIU Qinfang
        Vol. 26, Issue 1, Pages: 57-60(2008)
        摘要：In order to provide data of bio-burden for dose setting in radiation sterilization, determination of bio-burden on 148 kinds of health care products from 52 manufacturers were carried out. The culture of microorganisms, different elution technology, and correction coefficient of the microbiological methods have been used for determination of bio-burden. Frequent distribution of bio-burden was established. 5 kinds of elution processes were checked. Actual data of bio-burden for dose setting in radiation sterilization was gotten.  
        关键词：Radiation sterilization;Bio-burden;Dose setting   
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        发布时间：2023-03-30
      • RAO Yalan,LI Ming,CONG Yue,LI Fengsheng,CHEN Xiaohua,DONG Bo,ZHANG Junquan,GAO Ling,MAO Bingzhi
        Vol. 26, Issue 1, Pages: 61-64(2008)
        摘要：The study explores the expression and effect of calcium-binding protein S100A8 on early phase of radiation pulmonary fibrosis via in vivo and in vitro experiments. In vivo experiment, the thoracic regions of rats were irradiated under 20Gy 60Co γ-rays to establish radiation pulmonary fibrosis. After irradiation, the lung specimens of the sacrificed rats were separately harvested by the ends of the first, second, and fourth weeks respectively. The protein expression of S100A8 was tested through immunohistochemistry, the mRNA expression of S100A8 and its heterodimeric S100A9 were investigated by RT-PCR method. In vitro experiment, RT-PCR method was also applied to measure the mRNA expression of S100A8 in mouse macrophage cell line RAW264.7 after γ-rays irradiation and/or lipopolysaccharide (LPS). It shows that the protein expression of S100A8 was increased in the plasma of lung macrophages samples and the mRNA expression of S100A8 and S100A9 was also increased in the lung tissue samples in four weeks after irradiation in vivo experiment. And in vitro experiment it shows that the cooperation between γ-rays and LPS can increase the mRNA expression of S100A8 in RAW264.7. These phenomena suggest that S100A8 can exert the chemotactic activity, participate in the inflammatory response, and influence the establishment of radiation pulmonary fibrosis.  
        关键词：Radiation pulmonary fibrosis;S100A8;Macrophage;Inflammatory response   
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        发布时间：2023-03-30

        研究论文

      • XU Xinping,PENG Ruiyun,GAO Yabing,CHEN Haoyu,CUI Xuemei,WANG Dewen,CHEN Weizhi,DONG Bo,YANG Yi,QIU Ping
        Vol. 26, Issue 1, Pages: 33-38(2008)
        摘要：In order to investigate the death mode of hematopoictic cells in mouse bone marrow irradiated by neutron and γ-rays, 350 BALB/C mice, which were whole body irradiated with varies doses of neutron and γ-rays, were sacrificed at 6 and 12hours, 1, 2, 3, 4, 5, 7, 10, 14, 21 and 28days after irradiation respectively. By means of light microscope, electron microscope, flow cytometry, in situ terminal end labeling and DAN gel electrophoresis, the apoptosis and necrosis of hematopoietic cells were investigated. The results showed that the amount of hematopoietic cells occurring apoptosis and necrosis were obviously increased after neutron irradiation and the necrosis was main death mode in irradiation dose of 5.5Gy. Meanwhile, γ-irradiation mainly induced apoptosis of hematopoietic cells and the apoptosis was correlated to the irradiation dose. It means that there were different death modes of hematopoietic cells in mouse bone marrow irradiated by neutron and γ-rays. Neutron mainly induced necrosis of the hematopoietic cells though apoptosis also occurred in irradiation dose of 5.5Gy, while γ-rays mainly induced the apoptosis.  
        关键词：Bone marrow;Hematopoietic cells;Neutron;γ-rays;Death mode   
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        发布时间：2023-03-30
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