最新刊期
      期 5 ， 2017

        REVIEW

      • Xiyu YANG,Guoqi ZHAO
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050101
        摘要：Cell autophagy could not only inhibit but also promote tumor growth, which plays an important role in the occurrence, development, and clinical prognosis of nasopharyngeal carcinoma (NPC). The low-level and basic autophagy is conducive to its cell metabolism and self-protection, which is one of the major factors in NPC radio-or chemo-therapy resistance, while high-level and excessive autophagy could lead to the autophagic cell death, which is the foundation of NPC treatment based on autophagic target. The research and application of autophagy modulators is the key link to realize the regulation of autophagy level. Autophagy inhibitors or inducers can enhance sensitization to radio-or chemo-therapy and even induce autophagic death of NPC cells. The mechanism of action of autophagy in NPC is, however, very complex and not yet fully understood up to now. Here, we reviewed the research progress in autophagy and its potential value in NPC radiotherapy in order to explore the prospect of autophagy as a new target for NPC treatment, especially therapeutic autophagic cell death in NPC induced by X-ray as an autophagy modulator.  
        关键词：Nasopharyngeal carcinoma;Autophagy;Radiotherapy;Autophagy modulators   
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        发布时间：2021-12-10

        RADIOBIOLOGY AND RADIOMEDICINE

      • Gan'en MU,Wei LONG,Yuanyuan LI,Guangyun YU,Xiu SHEN,Zewei ZHOU
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050201
        摘要：The N-acetyl-S-allyl-L-cysteine (NAc-SAC) was synthesized by substitution and acylation reactions with L-cysteine as raw materials. Experiments on blood and immune-organs indexes, and survival rates of ICR mice within 30 d after 137Csγ-rays irradiation at different doses, as well as the comet assay were carried out to investigate the anti-irradiation effects of NAc-SAC. The survival rates of mice irradiated at 7.5 Gy with the dose of NAc-SAC at 200 mg/kg, 400 mg/kg, and 600 mg/kg increased to 58.3%, 50.0% and 66.7%, respectively, and the average survival time was significantly prolonged compared with that in the control group. The spleen indexes, colony forming cell-spleen (CFU-S), percentages of DNA, number of white blood cells of mice irradiated at 6.0 Gy increased under the action of NAc-SAC. The tail length, tail moment, olive tail moment, and tail DNA percentage of peripheral blood lymphocytes of mice irradiated at 7.0 Gy combined with NAc-SAC were higher than those for the control group (p < 0.05). To conclude, NAc-SAC has a protective effect against damage induced by irradiation.  
        关键词：N-acetyl-S-allyl-L-cysteine (NAc-SAC);Radiation protection agent;Mice;Anti-radiation activity;137Cs γ-rays   
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        发布时间：2021-12-10

        RADIATION CHEMISTRY

      • Chi ZHAO,Hanqin WENG,Mozhen WANG,Xuewu GE,Mingzhang LIN
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050301
        摘要：In this paper, double-bond-modified fibrous mesoporous silica (F-SiO2-K) microspheres were prepared first, and then grafted with poly (4-vinylpyridine) (P(4-VP)) in 4-VP or its methanol solution initiated by γ-ray irradiation to obtain pyridine modified mesoporous silica (F-SiO2-VP) microspheres. The Fourier transform infrared spectroscopy (FTIR) and thermal gravimetric analysis (TGA) results indicated the successful grafting of P(4-VP). The degree of grafting (DG) of P(4-VP), which was calculated from TGA curves, increased with the monomer concentration and the absorbed dose, however reached a maximum value at a moderate dose rate. The adsorption ability of F-SiO2-VP for U(VI) in nitric acid solution was investigated. The results show that the adsorption capacity is related to the concentration of nitric acid and the DG of F-SiO2-VP, and reaches a maximum of 163 mg/g. The adsorption kinetics fits the pseudo-second-order model, and the adsorption isotherm of F-SiO2-VP fits the Freundlich model at low U(VI) concentrations and the Langmuir isotherm well at high U(VI) concentrations.  
        关键词：γ-ray;Radiation grafting;Mesoporous silica;4-Vinylpyridine;Uranium   
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        发布时间：2021-12-10
      • Xiao XU,Xiyan LIU,Xiaoyan ZHAO,Hongjuan MA
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050302
        摘要：Sulfonic-type adsorbent was prepared from radiation-induced graft polymerization of 4-hydroxybutyl acrylate glycidylether (4HBAG) on PE/PP non-woven fabric. Sulfonation of the 4HBAG grafted PE/PP non-woven fabric was carried out in a mixed solution of Na2SO3. The process of sulfonation was investigated by the morphology and weight of the material. A sulfonic group density of 1.4 mmol/g adsorbent with a 52% molar conversion of the epoxy group was obtained. The adsorption behavior of cesium was studied with batch and column model. The sorption isotherm and sorption kinetics of cesium indicated that the adsorption process followed the Langmuir isotherm model and pseudo second-order kinetic model. The maximum adsorption capacity of cesium was evaluated as 1.35 mmol/g at a high flow rate of 1 000 SV/h. In the range of pH=4~10, the adsorption ratio remained stable at approximately 90%, and the value decreased with further increments of pH value. The effect of Na+ on the removal ratio of Cs+ was studied in its 1 mg/L and 10 mg/L solution. The removal ratio of Cs+ decreased quickly when the Na+ concentration increased from 0 to 20 mmol/L. Compared with the effects of Na+ and K+, bivalent ions such as Mg2+ and Ca2+ and the trivalent metal ion Fe3+ were found to be more impeditive to Cs+ adsorption. This sulfonic-type adsorbent exhibited the extremely rapid removal of Cs+ with a high flow rate of 1 000 SV/h.  
        关键词：Pre-irradiation;Graft polymerization;Sulfonic-type;Cesium;Adsorption;4-hydroxybutyl acrylate glycidylether;PE/PP   
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        发布时间：2021-12-10
      • Jiwei LI,Junyu CHEN,Yiyi BAO,Shaojin JIA,Pingkai JIANG,Yongkang LYU,Wei WU,Caihui ZHOU,Chaohua LUO
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050303
        摘要：Ethylene-octene copolymer (POE) blended with different contents of intumescent flame retardants (ammonium polyphosphate, pentaerythritol, and melamine) was irradiated by electron beams to prepare flame retardant composite materials. The oxygen index, cone calorimeter, and combustion performance were used to characterize the flame retardant properties. The results showed that the tensile strength as well as the oxygen indices of the composites (about 1~2) increased and the elongation at break decreased with increasing absorbed doses. The combustion process of the composites shortened, and the heat and smoke release of the composites were more concentrated. After irradiation crosslinking at 200 kGy, the total heat release decreased from 94.8 MJ/m2 to 79.1 MJ/m2, the total amount of smoke release decreased from 1122.9 m2/m2 to 928.4 m2/m2, the combustion process reduced by about 25%, the CO release rate decreased from 0.062 2 kg/kg to 0.043 9 kg/kg, and the CO2 producing rate increased from 1.44 kg/kg to 1.51 kg/kg. Moreover, as the absorbed dose increased, the volume resistivity of the material varied slightly.  
        关键词：Electron beam;Radiation crosslinking;intumescent flame retardants;Mechanical properties;Oxygen Index;Heat release;Insulation properties   
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        发布时间：2021-12-10
      • Cheng CHEN,Chuansheng CHEN,Wenjun YAN,Haiyan WANG,Tian XIA
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050304
        摘要：The surface chemical composition, hydrophilicity, and microstructure of wool fabrics before and after UV irradiation were characterized by surface property measurements. The results showed that during UV irradiation, cystine, disulfide bonds with hydrophobicity and nonpolar C-C bonds were partially dissociated, and the surface hydroxyls, nitrogen-containing groups, and C-O bonds increased, improving the hydrophilicity of wool fabrics, which was further confirmed by the decreased static water contact angle and increased capillary effect of UV irradiated wool fabrics. Moreover, the surface morphology and crystal structure of wool fibers hardly changed, but the roughness increased slightly in the chemical etching resulting from low-power UV irradiation within short time. Based on the above-described effects induced by UV irradiation on surface physical and chemical properties of wool fabrics, this method is conducive to woolen dyeing and finishing.  
        关键词：UV irradiation;Wool fabric;Surface;Physical and chemical property   
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        发布时间：2021-12-10

        RADIATION PROTECTION

      • Mintian GU,Ruiwen ZHANG,Peng LI,Guiling ZHENG
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050501
        摘要：Physiological changes to Tillandsia usneoides were tested after fumigation with different concentrations of radon in a standard radon chamber. The results showed that the leaf relative electrical conductivity increased at concentration of 2 000 Bq/m3, though not significantly different from that of the control group, which increased remarkably at concentration of 4 000 Bq/m3. Moreover, soluble proteins and malondialdehyde contents didn't change much with increasing radon concentrations, i.e., no significant physiological damage induced, indicating that Tillandsia usneoides was relatively strongly resistant to radon, which was probably related to the existence of foliar trichomes on the leaf surface. In addition, superoxide dismutase content increased greatly with increasing radon concentrations, suggesting scavenging system of reactive oxygen species played a role in reducing the damage of plants exposed to radon.  
        关键词：Tillandsia usneoides;Air pollution;Oxidative stress;Radiation   
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        发布时间：2021-12-10

        RADIATION TECHNOLOGY APPLICATION

      • Lihui ZHANG,Fang CAI,Jianjun HE,Xin MEI,Jianbin SHI,Sha CAI,Yong SUI,Zhengming QIU,Xueling CHEN
        Vol. 35, Issue 5, (2017) DOI: 10.11889/j.1000-3436.2017.rrj.35.050401
        摘要：The mustard was peeled, cut, pickled, spiced, packaged, and then irradiated by 60Co γ-rays at doses of 3 kGy, 5 kGy, and 7 kGy, respectively to sterilize, with 0 kGy as control for comparison. The results showed that the irradiated mustard showed better in color, total acid content, browning degree, and bactericidal effect than control. And with the increasing of absorbed doses, the total acid content, browning degree, and brittleness of the mustard decreased, while the bactericidal effects was enhanced, and the nitrite content increased slightly. Within 56 d after irradiation at 5 kGy, the mustard were kept well in original color and quality with the microbes of 103 cfu/g, nitrite content of 8.97 mg/kg, total acid content of 5.27 g/100 g, browning degree of 2.57, and brittleness of 157.41. Compared with control, the storage time of the irradiated mustard extended by 28 d at least.  
        关键词：Irradiation;Mustard;Quality;Storage   
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