最新刊期
卷 37 ， 期 1 ， 2019
- “超临界CO2发泡技术制备微孔聚合物材料，辐射交联技术提高聚合物熔体强度，拓宽发泡温度区间。”摘要：Manufacture of microcellular plastic foams using supercritical CO2 foaming technology has attracted considerable research attention from industries, owing to its numerous excellent advantages like efficient foaming, environmental preservation, good mechanical performance of polymer foam, and good appearance of finished products. Because the melt strength of some types of polymers (e.g. polypropylene (PP)) is very low, i.e. they are easy to rupture and collapse, the mechanical properties of the obtained foams are poor. Radiation cross-linking can change the polymer from a 2-dimensional structure to a 3-dimensional network structure, significantly improving its melt strength, and making it favorable for foaming using supercritical CO2. Hence, radiation technology has great application potential in supercritical CO2 foaming of polymers. This paper briefly summarized the characteristics of PP foaming using supercritical CO2 and the application of radiation cross-linking in the same.关键词：Polypropylene (PP);Supercritical CO2;Radiation cross-linking;Foaming;Mechanical property71|39|2更新时间：2025-03-03
REVIEW
- “在橡胶材料领域，专家通过γ射线辐照技术，实现了无硫化氢化丁腈橡胶的高性能和长寿命，为橡胶材料研究开辟了新方向。”摘要：Vulcanized hydrogenated butadiene-acrylonitrile rubber (HNBR) without the use of vulcanization reagents was cross-linked by γ-ray irradiation. The vulcanization behavior was investigated at the absorbed dose range of 0 ~ 300 kGy. The micromorphology and dynamic mechanical properties were characterized and analyzed by dynamic mechanical analysis and scanning electron microscope, respectively. The results indicated that the HNBR sample was vulcanized by γ-ray irradiation without vulcanization reagents. With an increase in the absorbed dose, the elastic torque simultaneously increased when the mold filling deformation decreased due to the cross-linked reaction of HNBR. The HNBR sample exhibited excellent mechanical properties and oil resistance when the absorbed dose of 200~250 kGy. Compared with the chemical-vulcanized HNBR, the retention rate of tensile strength and the elongation at break of radiation-vulcanized HNBR increased by 24% and 39%, respectively, in air at 150 oC for 70 h. Moreover, the compression set of the radiation-vulcanized HNBR (46.20%) was lower than that of chemical-vulcanized HNBR (58.56%) after being immersed in 903# oil at 150 oC for 24 h. The results prove that radiation vulcanization improves hot-air and hot-oil aging resistance and is, thus, expected to achieve both high performance and long service life.关键词：Hydrogenated butadiene-acrylonitrile rubber;Radiation vulcanization;Technical property;Aging33|63|0更新时间：2025-03-03
RADIATION CHEMISTRY
- “最新研究发现，电离辐射可能通过激活小鼠海马区星形胶质细胞，诱导炎症因子释放，导致认知功能障碍。”摘要：In order to explore the possible mechanisms underlying cognitive dysfunction induced by ionizing radiation in mice, twenty-four female Kunming mice were randomly divided into a control group and irradiation group (IR). The IR group mice were irradiated with 137Cs γ-rays at an absorbed dose of 4 Gy. After 35 d, the Y-maze test was used to evaluate the cognitive function of the mice. The expression of the astrocyte marker, glial fibrillary acidic protein (GFAP), was detected using immunohistochemical staining. The expression of GFAP protein in the hippocampus was assayed using western blot. The expression of GFAP, interleukin (IL)-1α, IL-1β, and IL-6 mRNA in the hippocampus was detected using reverse transcription polymerase chain reaction. The results showed that compared with the control group, the spontaneous alternation rate of the IR mice was significantly reduced in the Y-maze test (78.40 ± 4.16 vs. 67.53 ± 3.08, p < 0.05); and the number of GFAP-positive cells in the hippocampus was significantly higher (133.4 ± 9.6 vs. 280.3 ± 32.7, p < 0.01); GFAP protein levels (1.000 ± 0.036 vs. 1.300 ± 0.102, p<0.05) and GFAP mRNA expression (1.000 ± 0.0307 vs. 1.203 ± 0.078, p < 0.05) were significantly upregulated; and the expression of inflammatory factors IL-1α, IL-1β, and IL-6 mRNA was upregulated (1.000 ± 0.133 vs 1.677 ± 0.164, p < 0.01; 1.000 ± 0.132 vs. 1.488 ± 0.105, p < 0.05; 1.000 ± 0.218 vs 2.181 ± 0.188, p < 0.01). It is suggested that ionizing radiation induces cognitive dysfunction by activating astrocytes in the hippocampus.关键词：Ionizing radiation;Hippocampus;Astrocytes;Cognitive dysfunction40|40|2更新时间：2025-03-03
- “最新研究发现，CpG-ODN通过调节Th1/Th2型细胞因子平衡，抑制放射性肺纤维化的发生。”摘要：To investigate the mechanism of CpG-ODN in the prevention of radiation pulmonary fibrosis by focusing on the regulation of balance between Th1/Th2 cytokines. The entire thorax of female C57BL/6 mice was exposed to a single radiation at a dose of 15 Gy. The Th1/Th2-related cytokines and profibrogenic cytokines were detected by enzyme linked immunosorbent assay for 20 weeks after radiation. Alveolar macrophages, pulmonary fibrosis, and phosphorylated Mitogen-activated protein kinase (MAPK) family proteins were detected by immunohistochemistry. The results suggested that CpG-ODN promoted Th1-related cytokine secretion and inhibited Th2-related cytokine secretion, leading to a predominantly Th1 immune response, reduced alveolar macrophage accumulation, and profibrogenic cytokine (TGF-β1 and IGF-1) expression, which may be involved in the inhibition of phosphorylation of MAPK family proteins. This indicates that CpG-ODN prevents pulmonary fibrosis by regulating the imbalance between Th1/Th2 after irradiation.关键词：Radiation pulmonary fibrosis;CpG-ODN;Imbalance of Th1/Th2;Cytokine;MAPK family58|55|1更新时间：2025-03-03
- “槐角染料木黄酮对放射导致的肠损伤具有保护作用，为放射肠损伤治疗提供新方案。”摘要：This study investigated the protective effect of genistein extracted from fructus sophorae (FSGen) on intestinal damage caused by radiation. After FSGen treatment of rat intestinal epithelial cells (IEC-6) for 24 h, the cells were irradiated with X-rays at an absorbed dose of 6 Gy. Cell counting kit-8 and flow cytometry were used to detect cell proliferation and apoptosis 48 h after irradiation, and the extent of DNA damage was detected by comet assay 72 h later. C57BL/6J female mice were subcutaneously injected with FSGen at a dose of 200 mg/kg. After 24 h, they received whole-body irradiation with X-rays at a dose of 7.5 Gy. After 8 d, pathological changes in the small intestine were observed by HE staining. The expression of intestinal IFN-γ was detected by immunohistochemistry, and the apoptosis of small intestinal cells was detected by TdT-mediated dUTP nick-end labeling. Results showed that a low dose of FSgen could promote the proliferation of IEC-6 cells and improve survival rate after irradiation, whereas a high dose can inhibit cell proliferation. Compared with the radiation control group, 5 μmol/L FSGen pretreatment could effectively improve the survival rate of IEC-6 cells, reduce the apoptosis induced by irradiation, and significantly reduce the comet tail DNA content and tail moment. Compared with the radiation control group, the mice administered with FSGen in advance had less villus shedding, better intestinal structure damage, lower expression of IFN-γ in small intestine tissue, and less apoptosis. The results reveal that FSGen has a significant protective effect on radiation-induced intestinal injury.关键词：Radiation injury;Genistein;Radiation-protective agents;Fructus sophorae39|69|0更新时间：2025-03-03
RADIOBIOLOGY AND RADIOMEDICINE
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Carbon ion-beam irradiation screening of a butanol-tolerant mutant of
Clostridium acetobutylicum AI导读“在生物能源领域，研究人员利用12C6+离子束辐照诱变技术，成功筛选出高产且高抗丁醇胁迫的丙酮丁醇梭菌突变株G01，为提高生物燃料产量和耐受性提供新途径。”摘要：To improve butanol tolerance of Clostridium acetobutylicum strains, 12C6+ ion-beam irradiation screening identified a C. acetobutylicum mutant (G01) with high productivity and resistance to butanol stress. Compared with the wild type C. acetobutylicum CICC 8012, mutant G01 was resistant to 19 g/L butanol and exhibited a 33% higher butanol production. The results indicate that 12C6+ ion beam irradiation can increase butanol tolerance and productivity of C. acetobutylicum. These data provide a reference for further culture and development of industrially relevant strains of C. acetobutylicum that have higher butanol tolerance and productivity.关键词：12C6+ ion beam;Irradiation mutation;Butanol fermentation;Butanol tolerance31|54|0更新时间：2025-03-03 - “蒙特卡罗程序模拟空心纤维透析器剂量分布，为产品装载模式设计提供指导。”摘要：The Monte Carlo method (MCNP) was used to simulate the absorbed dose distribution in an artificial kidney dialyzer product irradiated with 60Co gamma-rays for sterilization. The results showed that the relative deviation between the MCNP simulation value and the measured data was within ±15% and that the dose distribution laws of the two methods were similar. Predetermining the dose mapping of an artificial kidney dialyzer product during irradiation through MCNP simulation is useful. The MCNP simulation method provides valuable information for designing loading patterns and determining the minimum and maximum dose zones of the product.关键词：Monte Carlo method (MCNP);Dose mapping;Loading pattern;Dose zones61|53|1更新时间：2025-03-03
RADIATION TECHNOLOGY APPLICATION
- “最新研究进展：专家设计三维电场测量系统，准确获得微波辐照生物体内电磁暴露剂量，为生物电磁学研究提供新方向。”摘要：In order to ascertain the dosimetry of animals exposed to an electromagnetic field (EMF), a three-dimensional electric field measurement system in vivo was designed. The proposed system can be used to measure the electric fields in rats exposed to an EMF of 1 800 MHz. In addition, several parameters of the proposed system were measured, including direction and sensitivity. The isotropy of the proposed system was found to be less than -3 dB. The measurement range and system sensitivity were 0~605.95 V/m and 0.96 mV/m, respectively. Further, the magnitude, direction, and three-dimensional components of the electric field were determined by several tests using different solutions. The results indicated that the response coefficient of the measurement system in different media decreased as the relative permittivity increased. When the relative permittivity was higher than 20, no significant change in the response coefficient was observed. The difference in maximum relative errors of the electric field between the measured values in the brain and liver of rats exposed to EMF of 1 800 MHz and the calculated values was small, 5.1% for brain and 13.1% for liver. The results indicated that the measured electric field values were in good agreement with the calculated values. Therefore, it is demonstrated the proposed three-dimensional electric field measurement system can accurately measure the electric field in animals irradiated by microwaves.关键词：Three-dimensional electric field measurement system;Direction of electric field;In vivo;Microwave irradiation25|65|0更新时间：2025-03-03
RADIATION INTERDISCIPLINARY RESEARCH
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