最新刊期
卷 38 ， 期 1 ， 2020
- “在材料科学领域，研究人员采用共辐射接枝技术制备了马来酸酐接枝改性的低密度聚乙烯，研究了吸收剂量对材料化学结构和物理性能的影响，为LDPE改性提供了有效策略。”摘要：Modification of low-density polyethylene (LDPE) by grafting it with a maleic anhydride (MAH) was conducted using a co-irradiation technique at room temperature under a vacuum atmosphere at absorbed doses of 10 kGy, 25 kGy, 50 kGy, and 100 kGy. The effects of the absorbed dose on the chemical structure and physical properties of LDPE-g-MAH were investigated. The Fourier transform infrared spectroscopy showed that the MAH was grafted onto the LDPE surface successfully. The grafting degree of the MAH increased with the absorbed dose. The melting temperature (Tm) and thermal degradation temperature (T5%) of the LDPE-g-MAH films decreased with the increasing absorbed doses because of the occurrence of crystal defects of LDPE caused by irradiation. However, the morphologies and crystal forms of LDPE did not change after irradiation. This work provides an effective strategy for radiation graft modification of LDPE.关键词：Radiation grafting;Modification;Low-density polyethylene;Maleic anhydride151|195|1更新时间：2025-02-28
- “最新研究发现，共轭吩噻嗪基烯酮染料可高效增感环氧树脂光聚合反应。”摘要：A conjugated phenothiazine ketene dye (Phz-KT) with D‒π‒A‒π‒D structure was synthesized by the reaction between N-ethylphenothiazine and acetone. UV-vis spectroscopic studies showed that Phz-KT has strong absorption at 380~550 nm. A steady photolysis experiment showed that the dye has photobleaching properties under light irradiation. Considering Phz-KT dye as a photosensitive sensitizer and diaryl iodonium salt as an initiator, the epoxy ring-opening polymerization of bisphenol A epoxy resin E51 was investigated under irradiation from 460 nm and 520 nm LED light sources. It was found that the Phz-KT dye initiated epoxy resin polymerization via charge-transfer-sensitized diaryliodonium salt.关键词：Ketene;Dye;Epoxy resin;Photopolymerization;Light emission diode;Light source37|46|0更新时间：2025-02-28
- “在环保领域，科研团队利用预辐射接枝技术，成功制备出4-氨基-1,2,4-三氮唑改性超高分子量聚乙烯纤维，实现了从废水中高效回收贵金属元素。”摘要：4-Amino-1,2,4-triazole (ATZ) was introduced into ultra-high molecular weight polyethylene (UHMWPE) fibers by pre-radiation grafting to prepare UHMWPE-g-(GMA-ATZ) fibers. The effect of the initial pH Au(III) adsorption by UHMWPE-g-(GMA-ATZ) fibers and the adsorption mechanism of Au(III) on the functional fiber were investigated. The adsorption efficiency of Au(III) reached 98.7% when the solution pH was 2, Au(III) concentration was 50 mg/L, and adsorbent concentration was 2 g/L. Scanning electron microscopy, X-ray diffraction and X-ray absorption near-edge structure showed that Au mainly existed on the fiber as metallic Au particles. Fourier transform infrared spectroscopy revealed that the imino groups (-NH-) disappeared after Au(III) adsorption, generating carboxyl groups. The adsorption mechanism of Au(III) on the UHMWPE-g-(GMA-ATZ) fiber is based on the redox reaction between Au(III) and -NH- on the fiber, accompanied by the formation of carboxyl group and the reduction of Au(III) to zero valence Au. This functional fiber can be used to facilitate a simple and efficient method for precious metal recovery from wastewater.关键词：4-Amino-1;2;4-triazole;UHMWPE fiber;Au(III);Adsorption mechanism34|56|0更新时间：2025-02-28
RADIATION CHEMISTRY
- “最新研究发现，沉默hALP基因表达可提高结直肠癌CL187细胞的放射敏感性，为结直肠癌放射治疗提供新思路。”摘要：To investigate the effect of human acetytransferase-like protein(hALP) SiRNA on radiosensitivity of colorectal cancer CL187 cells. For this, the expression of hALP in colon cancer tissues was investigated, based on information available in clinical databases. After hALP knockdown, CL187 cells were irradiated with gradually increasing doses（0 Gy,2 Gy,4 Gy,6 Gy and 8 Gy）, and clonal proliferation and cell viability assays were used to detect radiosensitivity. After with the hALP SiRNA duplex, the percentage of cells in which apoptosis was induced by radiation at the dose of 8 Gy was detected by flow cytometric analysis, and the expression of hALP, P53, and BAX was examined by western blotting. Following irradiation, the ratios of surviving fraction between hALP SiRNA and negative control SiRNA groups were 0.63, 0.5, respectively, for total doses of 2 Gy(RBE=1.26). Silencing hALP enhanced the radiosensitivity of CL187 cells. Moreover, hALP knockdown increased the percentage of CL187 cells undergoing apoptosis from 19.53% to 36.49%（p<0.05）. The expression of hALP, P53 and BAX induced by radiation further increased after hALP knockdown expression. Further, hALP knockdown expression increased radiosensitivity of CL187 cells. The expression of hALP associated with the radiosensitivity of colorectal cancer cells, which is beneficial to screen potential molecular targets and to provide indispensable experimental data for improving the efficacy of radiotherapy.关键词：SiRNA;hALP;Colorectal cancer;Radiosensitivity22|37|0更新时间：2025-02-28
- “最新研究发现，电离辐射可导致肿瘤相关成纤维细胞中部分基因表达变化，为评估肿瘤放疗效果和预后提供潜在分子标记。”摘要：Tumor-associated fibroblast gene expression microarray data were obtained from the GEO database (GSE37318). Data were screened for differentially expressed genes using GEO2R software. GO and KEGG pathways were analyzed using the DAVID tool. A protein-protein interaction network was then constructed, and hub genes were identified using Cytoscape software. Prognostic value analysis of hub genes was performed using GEPIA. A total of 144 up-regulated genes and 54 down-regulated genes were identified from the dataset GSE37318. These were mainly expressed during cell stress, DNA damage, cell cycle, senescence, apoptosis, oxidative stress, and in the p53 signaling pathway. A protein-protein interaction network consisting of 103 nodes and 376 edges was constructed, and the top 20 hub genes were identified. Of the top 10 hub genes, low expression levels of eight genes including MCM10, DLGAP5, FANCI, CENPA, CDC6, FBXO5, NCAPG, and DTL were related to poor overall survival (OS) in lung cancer patients (p<0.05). However, high levels of PCNA expression were also associated with poor OS in lung cancer patients (p<0.05). Ionizing radiation may induce both up- and down-regulation of genes in tumor-associated fibroblasts. These differentially expressed genes provide potential molecular markers for evaluating the efficacy of tumor radiotherapy, patient prognosis, risk of recurrence, and metastasis.关键词：Ionizing radiation;Tumor;Fibroblast;Differential expression;Gene;Bioinformatics40|48|1更新时间：2025-02-28
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Protective effect of compound raspberry seed powder on radiation-induced spinal cord injury in mice AI导读
“据最新研究报道，复方树莓籽粉能有效减轻小鼠放射性脊髓损伤，抑制细胞凋亡。”摘要：To observe the protective effect of compound raspberry seed powder on radiation induced spinal cord injury in mice. Fifty healthy adult male mice were randomly divided into five groups of ten: control group, model group, and different concentrations (low, medium, and high) of compound raspberry seed powder solution treatment group. The model group was given distilled water by gastric lavage and the treatment groups were given different concentrations of compound raspberry seed powder solution by gastric lavage. Except for the control group, the mice were irradiated with whole body X-ray at a dose of 4 Gy immediately after gastric administration on the 15th day after treatment. On the 3rd day after irradiation, the spinal cord tissues were taken for hematoxylin and eosin (HE) and Nissl staining to observe morphological changes and the expression of Fas and caspase-9 in spinal cord tissues was detected by immunohistochemistry(IHC). HE staining showed swelling and disorder of nerve fibers in the white matter of the spinal cord, atrophy, and disappearance of some neurons in gray matter, accompanied by an inflammatory reaction. Nissl staining showed that the Nissl body dissolved and neurons disappeared in the model group. IHC showed that the staining degree of Fas and caspase-9 in the model group was significantly higher than that in the control group (p<0.01). The staining degree of Fas and caspase-9 in compound raspberry powder solution treatment groups was lower than that in the model group and gradually decreased with the increasing concentrations(p<0.05). Compound raspberry seed powder can alleviate radiation-induced spinal cord injury and inhibit the overexpression of Fas and caspase-9 to inhibit apoptosis. With an increase in concentration, the protective effect is more obvious.关键词：Raspberry;Radiation-induced spinal cord injury;Radiation protective agent;Apoptosis42|33|0更新时间：2025-02-28
RADIOBIOLOGY AND RADIOMEDICINE
- “最新研究发现，氡浓度增加显著损害植物DNA，贝可利空凤叶表鳞片可减轻氡伤害。”摘要：The damage in plant DNA induced by the naturally occurring radioactive gas radon were investigated here. For this, we chosed two common indicator plants, Tillandsiabrachycaulos and Tillandsia usneoides, as our model system. Leaf DNA damage was tested by the single cell gel electrophoresis method after a 72 h exposure of plants to radon at different concentrations. Increase in radon concentration led to a significant increase (p<0.05) in the comet DNA index (comet length, tail length, tail DNA, tail moment, and Olive tail moment), suggesting that Tillandsia suffered from radiation damage at the DNA level. However, DNA damage in T. brachycaulos with manually removed trichomes upon radon exposure at a concentration of 2 560 Bq/m3 was comparable to that in T. brachycaulos (with trichomes) exposed to 4 525 Bq/m3 of radon. This indicates that foliar trichomes present in these plants most likely act as a shield against pollutants, therefore alleviating radon-induced DNA damage.关键词：Air plant;Comet assay;DNA damage;Radon26|40|0更新时间：2025-02-28
RADIATION PROTECTION
- “医疗器械辐照灭菌剂量监测采用统计过程控制方法，有助于及时发现异常波动，控制灭菌过程稳定，保证产品质量稳定可靠。”摘要：The irradiation sterilization process for medical devices must ensure that the maximum and minimum accepted doses for medical devices are between the maximum acceptable dose and the sterilization dose of the product. To ensure that the absorbed dose for each batch of medical devices meets the requirements, dose monitoring of the effect of each irradiation sterilization batch is required. This study adopts the statistical process control method to analyze monitored dose values and provides scientific quality management methods for medical device manufacturers and irradiation sterilization providers. The results show that the application of statistical process control methods can help to find abnormal fluctuations in time and to control the sterilization process to a stable state, thereby ensuring that the quality of medical device products is stable and reliable, as well as enhancing the predictability of quality management.关键词：Medical devices;Radiation sterilization;Absorbed dose;Statistical process control;Quality control90|77|1更新时间：2025-02-28
RADIATION INTERDISCIPLINARY RESEARCH
- “辐射接枝聚合技术在纺织品印染领域实现绿色印染，有效降低废水污染，提高色牢度。”摘要：Conventional textile dyeing industries use small molecular weight organic dyestuffs, where the unreacted dyestuff molecules generate large quantities of refractory wastewater and cause serious problems to the environment. This highlight reports on the latest article for textile dyeing through the radiation-induced graft polymerization (RIGP) method, where carbon-carbon double bond functionalized nanoparticles including carbon black, cobalt blue, cobalt green, and iron red were immobilized on the surface of cotton fabric. The wastewater generated in this process can be discharged directly, as the concentrations of the contaminants are lower than those of the international standard and Chinese national standard requirements. The fastness of the color is ensured by the covalent bonding between the nanoparticles and the cellulose macromolecules, which remains unchanged after 100 domestic laundering cycles.关键词：Radiation-initiated graft polymerization;Green dyeing;Nanoparticles57|42|4更新时间：2025-02-28
RESEARCH HIGHLIGHT
- “在抗击新冠疫情中，中国辐射加工行业为防护服等医疗物资提供快速辐照灭菌服务，大幅缩短灭菌时间，为解决防护服供应问题提供解决方案。”摘要：The requirement of disposable medical protective clothing and other medial items has been increasing sharply since the novel coronavirus pneumonia (NCP/Coronavirus disease 2019, COVID-19) outbreak in January 2020 in Wuhan city, it is demanded to find a fast and reliable way to sterilize or disinfect medical protective clothing. Ethylene oxide (EO) gas has been widely adopted in China to sterilize disposable medical protective clothing, but the total period of this sterilization process normally requires 7~14 d because the release of contaminated EO from clothing takes a long time. However, ionizing radiation sterilization by gamma ray or electron beam can be completed in one day, being much faster than traditional EO sterilization. To promote radiation sterilization of medical protective clothing, China Isotope and Radiation Association (CIRA) organized national experts to draft a temporal standard of radiation sterilization of disposable medical garments by gamma ray or electron beam, in both Chinese and English versions. This standard has already been accepted by radiation sterilization service industry, a large number of medical garments have been disinfected by irradiation. Radiation sterilization is believed to be widely used in the future for disinfection of medical clothing and other items.关键词：Radiation sterilization;Disposable medical protective clothing;Novel coronavirus pneumonia (NCP);Coronavirus disease 2019 (COVID-19)45|27|8更新时间：2025-02-28
INDUSTRY BULLETIN
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