To explore the sterilization dose setting method for medical products, the irradiation sterilization dose for medical products was set according to the method 2A of international standard ISO11137 Part 2. The verification dose for medical gauze pad by was set by incremental dose method and with a series of formula. Then the sterilization dose for an SAL of 10,-6, was established by completing the verification dose experiment. The final sterilization dose for medical gauze pad was decided to be 29.7 kGy. This study gives reference for the setting irradiation sterilization dose for medical products which need to adopt the method 2A of international standard ISO11137 Part 2.