1.西北核技术研究所 西安 710024
郭平稳,男,1970年8月出生,1994年毕业于山西大学物理学专业,学士,工程师
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郭平稳, 李松兰, 张磊, 等. 60Co单板源堆码辐照剂量不均匀度分析[J]. 辐射研究与辐射工艺学报, 2005,23(2):123.
GUO Pingwen, LI Songlan, ZHANG Lei, et al. Dosimetry uniformity in products irradiated stationarily by a single plate 60Co source[J]. Journal of Radiation Research and Radiation Processing, 2005,23(2):123.
本实验在3.9PBq、1m×1m的单板源辐射场中,利用重铬酸银剂量计,在正对源1.4m×1.4m实际辐照面控制范围内,对桔红丸、利咽丸、妇炎灵三种中成药产品箱中吸收剂量及其不均匀度进行了测量,以检验辐照工艺质量。可根据辐照灭菌产品的包装尺寸与密度、菌种及细菌总数的含量设计照射方案,确定辐照工艺和运行参数。中成药所含细菌与辐照剂量的关系一般遵循公式,S,D,=,D,10 ,lg(,N,0,/,N,)+,K,,式中,S,D,为灭菌剂量,,D,10,为杀死90%细菌所需的吸收剂量,,N,0,为样品未辐照前的初始菌数,,N,为样品辐照后的存活菌数,,K,为经验校正因子,可正可负,取决于中成药辐照条件,[1],。在具体选择辐照剂量时,首先应考虑辐照产品的辐照目的、要求,以及辐照产品所含菌种及含菌基数,然后根据公式推算出所需辐照剂量。实验采用堆码辐照,四周和中间对调并前后翻转的双面辐照工艺。监测实验辐照产品最小吸收剂量的剂量计布放于各箱体中心,照射完成后通过测量剂量计的吸光度读出受照产品的吸收剂量。实验测得各受照产品最大、最小吸收剂量值依次为4.61kGy与2.98kGy,2.00kGy与1.03kGy,2.24kGy与1.37kGy,不均匀度,U,依次为1.55、1.94、1.64,证明产品箱中的剂量不均匀度均能满足质量控制标准(,U,≤2) 的要求, 表明该辐照工艺是可行的,辐照面大小的选择是合适的。
To verify quality of irradiated products by a 3.9PBq single plate (1m×1m) source, Ag,2,Cr,2,O,7, dosimeters were used for measuring extreme doses in three kinds of Chinese medicine in a actual irradiation area of 1.4m×1.4m facing the source. The product cartons were piled on the irradiation area, and their positions were exchanged to improve dosimetry uniformity of the products. The dosimeters for monitoring the minimum dose were placed in center of the cartons. The minimum doses of the three kinds of Chinese medicine products were 2.98, 1.03 and 1.37kGy respectively, and the maximum doses were 4.61, 2.00 and 2.24kGy, respectively. The dosimetry uniformities were 1.55, 1.94 and 1.64, respectively, which are within the quality control requirement of ,U,≤2.
吸收剂量不均匀度钴源辐照
Dosimetry uniformityγ-ray irradiation
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