JIANG Yaqi, CHEN Ying, MU Rui, et al. Dose-rate effect on chromosomal aberrations induced by 60Co γ-rays irradiation in human peripheral blood lymphocyte[J]. Journal of Radiation Research and Radiation Processing, 2008,26(1):47-51.
JIANG Yaqi, CHEN Ying, MU Rui, et al. Dose-rate effect on chromosomal aberrations induced by 60Co γ-rays irradiation in human peripheral blood lymphocyte[J]. Journal of Radiation Research and Radiation Processing, 2008,26(1):47-51.DOI:
To estimate exactly the biological dose of persons exposed to different dose rate, human peripheral blood was exposed to ,60,Co γ-rays ,in vitro, at low, middle and high dose rates respectively and chromosome samples were prepared, then dose-response curves were established according to the dicentrics and ring frequencies. The result showed that the aberration frequency at same dose level increased with dose rate and there was an obvious dose-rate effect. Absorbed dose estimated with low dose-rate dose-response curve was higher markedly than that with high dose-rate dose-response curve. So, considering the effect of dose-rate, approximate dose-rate dose-response curve should be chosen when absorbed dose estimation and the result will be credible.