ZHANG Yuguang, ZHANG Xinru, YAN Yujung, et al. THE RESEARCH OF E838 IN TUMOR RADIOTHERAPY[J]. Journal of Radiation Research and Radiation Processing, 1999,17(4):204-208.
ZHANG Yuguang, ZHANG Xinru, YAN Yujung, et al. THE RESEARCH OF E838 IN TUMOR RADIOTHERAPY[J]. Journal of Radiation Research and Radiation Processing, 1999,17(4):204-208.DOI:
E838 is a better radioprotecter that is derivative of estrogen. E838 inhibits cell proliferation of MCF7 cell line in vitro,D,0, is 3.9,µ,g/mL,IC,50, is 5.6,µ,g/mL. It also inhibits the growth of tumor bearing mice that extend the living time and enhance the effect of radiotherapy. Up till now, E838 haven't been fond the effect of stimulate and promote tumor metastasis. E838 has the possibility as an auxiliary medicine using in radiotherapy of tumors.