低剂量辐射及BLMA<sub>5</sub>对小鼠种植肿瘤细胞的抑制作用

朴春姬; 张海英; 尹洪淑; 王献理

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低剂量辐射及BLMA₅对小鼠种植肿瘤细胞的抑制作用

研究简报 | 更新时间：2023-04-07

- 低剂量辐射及BLMA₅对小鼠种植肿瘤细胞的抑制作用
- INHIBITORY EFFECTS OF LOW DOSE OF RADIATION AND LOW DOSE OF BIEOMYCIN A₅ ON THE GROWTH OF TUMORS IMPLANTED IN MICE
- 辐射研究与辐射工艺学报 2000年18卷第1期页码：77-79
- 作者机构：
  
  1.白求恩医科大学　长春　130021
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朴春姬, 张海英, 尹洪淑, 等. 低剂量辐射及BLMA₅对小鼠种植肿瘤细胞的抑制作用[J]. 辐射研究与辐射工艺学报, 2000,18(1):77-79.

PIAO Chunji, ZHANG Haiying, YIN Hongshu, et al. INHIBITORY EFFECTS OF LOW DOSE OF RADIATION AND LOW DOSE OF BIEOMYCIN A₅ ON THE GROWTH OF TUMORS IMPLANTED IN MICE[J]. Journal of Radiation Research and Radiation Processing, 2000,18(1):77-79.
朴春姬, 张海英, 尹洪淑, 等. 低剂量辐射及BLMA₅对小鼠种植肿瘤细胞的抑制作用[J]. 辐射研究与辐射工艺学报, 2000,18(1):77-79. DOI：

PIAO Chunji, ZHANG Haiying, YIN Hongshu, et al. INHIBITORY EFFECTS OF LOW DOSE OF RADIATION AND LOW DOSE OF BIEOMYCIN A₅ ON THE GROWTH OF TUMORS IMPLANTED IN MICE[J]. Journal of Radiation Research and Radiation Processing, 2000,18(1):77-79. DOI：

摘要

为了探讨低剂量理化因子（,D,1,）诱导的兴奋效应对种植肿瘤细胞的影响，用低剂量X线和博莱霉素A,5,（BLMA,5,）等理化因子对小鼠种植肿瘤的发生、发展进行了研究。结果表明：小鼠经0.05Gy X线照射或及BLMA,5, 0.08mg/kg作用后6h接种肿瘤细胞，其成瘤率低，肿瘤生长缓慢，比直接接种肿瘤细胞组明显降低（,p,<,0.05）。证明低剂量辐射和化学因子均可诱导兴奋效应，使机体防卫功能上调，对随后种植的肿瘤细胞具有抑制作用。

Abstract

In order to probe into the effect of hormesis of low dose of radiation and low dose of bleomcin A,5,(BLMA,5,) on mice, we investigated the growth of tumors implanted in Kunming mice, which had been treated with these two factors 6h before tumor implantation. The results showed that the tumor incidence and tumor growth of the treated group were significantly lower than those of control group ,(p,<,0.05). It was proved that both low dose of radiation and low dose of BLMA5 can induce hormesis, i.e., enhance defensive function of animal bodies and inhibit the growth of implanted tumors.

关键词

低剂量辐射低剂量BLMA5肿瘤发生率兴奋效应

Keywords

Low dose of radiationLow dose of bleomycin A5Tumor incidenceHormesis

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低剂量辐射的兴奋效应研究工作的进展

低剂量辐射及BLMA5对小鼠种植肿瘤细胞的抑制作用

INHIBITORY EFFECTS OF LOW DOSE OF RADIATION AND LOW DOSE OF BIEOMYCIN A5 ON THE GROWTH OF TUMORS IMPLANTED IN MICE

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摘要

Abstract

关键词

Keywords

references

低剂量辐射及BLMA₅对小鼠种植肿瘤细胞的抑制作用

INHIBITORY EFFECTS OF LOW DOSE OF RADIATION AND LOW DOSE OF BIEOMYCIN A₅ ON THE GROWTH OF TUMORS IMPLANTED IN MICE