SUN Yimin, LIU Shuzheng. INTERACTION OF ACCESSORY CELLS WITH SPLENIC LYMPHOCYTE AFTER WHOLE-BODY X-IRRADIATION OF MICE[J]. Journal of Radiation Research and Radiation Processing, 2000,18(2):108-112.
SUN Yimin, LIU Shuzheng. INTERACTION OF ACCESSORY CELLS WITH SPLENIC LYMPHOCYTE AFTER WHOLE-BODY X-IRRADIATION OF MICE[J]. Journal of Radiation Research and Radiation Processing, 2000,18(2):108-112.DOI:
We have examined the interaction among peritoneal macrophages, splenic accessory cells and splenic lymphocytes after whole body-irradiation (WBI) of mice with X-rays. The results showd: WBI with 75mGy X-rays could increase the proliferative response of splenic lymphocytes to ConA treatment, while 2 Gy WBI decreased it. If the splenic cell suspension was depleted of adherent accessory cells, proliferative response of lymphocytes was lowered. Peritoneal macrophages and splenic accessory cells obtained from mice exposed to lower dose radiation induced increase of proliferative response of T lymphocytes to ConA and IL-2 production.