THE PRELIMINARY STUDY OF THE RELATIONSHIP BETWEEN GLUTATHIONE CONTENT IN HUMAN SGC7901 CELL LINE PRETREATED WITH RADIOSENSITIZER AND ITS SUFFERED RADIATION DOSE
KONG Zhaolu, JIN Yizun, SHEN Zhifen. THE PRELIMINARY STUDY OF THE RELATIONSHIP BETWEEN GLUTATHIONE CONTENT IN HUMAN SGC7901 CELL LINE PRETREATED WITH RADIOSENSITIZER AND ITS SUFFERED RADIATION DOSE[J]. Journal of Radiation Research and Radiation Processing, 2002,20(3):216-219.
KONG Zhaolu, JIN Yizun, SHEN Zhifen. THE PRELIMINARY STUDY OF THE RELATIONSHIP BETWEEN GLUTATHIONE CONTENT IN HUMAN SGC7901 CELL LINE PRETREATED WITH RADIOSENSITIZER AND ITS SUFFERED RADIATION DOSE[J]. Journal of Radiation Research and Radiation Processing, 2002,20(3):216-219.DOI:
In this paper, the change of glutathione (GSH) content in the X ray irradiated human stomach cancer cell line SGC7901 which were pretreated with buthionine sulfoximine(BSO) were studied. The results showed that the GSH content in these cells decreased rapidly and the change was independent to the radiation dose. On the contrary, there was a trend for the un—pretreated control cells that the GSH level in the cancer cells rose alone with the increase of radiation dose.