Ma Yuqin, Yu Mingzhu, Song Xueling. EFFECTS OF GAMMA-IRRADIATION ON DNA CROSS-LINKING[J]. Journal of Radiation Research and Radiation Processing, 1984,2(4):50-53.
Ma Yuqin, Yu Mingzhu, Song Xueling. EFFECTS OF GAMMA-IRRADIATION ON DNA CROSS-LINKING[J]. Journal of Radiation Research and Radiation Processing, 1984,2(4):50-53.DOI:
DNA cross linking is an type of radiation damage as important as DNA strand-break. The DNA interstrand cross-linking in the dilute solution has been studied, and the result showed that DNA interstrand cross-linking only presented with in the irradiation dose range of 20~100 Gy. The effect depends on concentrantions and G-C percentage of DNA and is independent of dose-rate. The radioprotective effects of cysteine and radiosensitive effects of 5'-Bromouracil were demostrated as well.