职业受照射人员外周血淋巴细胞染色体畸变的适应性反应

姚素艳; 滝泽行雄; 山下顺助; 蜂谷纪之; 权太浩

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职业受照射人员外周血淋巴细胞染色体畸变的适应性反应

更新时间：2023-04-23

- 职业受照射人员外周血淋巴细胞染色体畸变的适应性反应
- CYTOGENETIC ADAPTIVE RESPONSE IN LYMPHOCYTES OF ROENTGENOLOGISTS EXPOSED OCCU PATIONALLY TO X-RAYS
- 辐射研究与辐射工艺学报 1993年11卷第4期页码：244-247
- 作者机构：
  
  1.卫生部工业卫生实验所，北京　100088
  2.秋田大学医学部公众卫生学教室，日本
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姚素艳, 滝泽行雄, 山下顺助, 等. 职业受照射人员外周血淋巴细胞染色体畸变的适应性反应[J]. 辐射研究与辐射工艺学报, 1993,11(4):244-247.

Yao Suyan, Yukio Takizawa, Junsuke Yamashita, et al. CYTOGENETIC ADAPTIVE RESPONSE IN LYMPHOCYTES OF ROENTGENOLOGISTS EXPOSED OCCU PATIONALLY TO X-RAYS[J]. Journal of Radiation Research and Radiation Processing, 1993,11(4):244-247.
姚素艳, 滝泽行雄, 山下顺助, 等. 职业受照射人员外周血淋巴细胞染色体畸变的适应性反应[J]. 辐射研究与辐射工艺学报, 1993,11(4):244-247. DOI：

Yao Suyan, Yukio Takizawa, Junsuke Yamashita, et al. CYTOGENETIC ADAPTIVE RESPONSE IN LYMPHOCYTES OF ROENTGENOLOGISTS EXPOSED OCCU PATIONALLY TO X-RAYS[J]. Journal of Radiation Research and Radiation Processing, 1993,11(4):244-247. DOI：

摘要

报道日本国秋田大学医学部附属临床医院中央放射线部诊疗技师的外周血淋巴细胞染色体畸变的适应性反应研究。该部有诊疗技师18名，均为男性，年龄25—59岁，职业工龄5—20年。累积吸收剂量0.02—0.22 mSv/月（1971.3—1991.2，1971.2以前的剂量未作估算），以染色体畸变为观察指标。结果表明，职业受照者的淋巴细胞染色体畸变率显著高于对照组（P,<,0.05）。当职业受照者的淋巴细胞经1.5 Gy ,60,Co γ射线体外照射（剂量率0.30 Gy/min）后，染色体型畸变率明显低于非职业人员离体血接受同样条件照射的结果，而染色单体型畸变率则未见降低，表明职业受照者的淋巴细胞染色体型畸变率存在适应性反应而染色单体型畸变率则未发现适应性反应。

Abstract

This paper studied the frequencies of chromosome aberrations in the lymphocytes of roentgenologists who had worked in this hospital at X-ray department for 5—20 years. They had accepted accumulative absorbed doses of 0.02—0.22 mSv/month, from Mar. 1971 to Feb 1991.The dose was not included before Feb. 1971. The results showed that frequencies of chromosome-type aberrations in lymphocytes of roentgenologists exposed to 1.5 Gy γ-rays (dose rate 0.30 Gy/min) were markedly lower than that in the cells of control group irradiated with 1.5 Gy alone (P< 0.001). According to dose levels the roentgenologists were divided into 3 groups, it did not find that the smaller the dose, the stronger the adaptive response.

关键词

适应性反应染色体畸变职业性照射

Keywords

Abaptive responseChromosome aberrationOccupational radiation exposure

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