次要联锁对头部肿瘤容积调强治疗中剂量验证的影响

孟慧鹏; 董化江; 孙小喆; 郑爱青; 梁克明

doi:10.11889/j.1000-3436.2016.rrj.34.020202

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次要联锁对头部肿瘤容积调强治疗中剂量验证的影响

更新时间：2021-12-10

- 次要联锁对头部肿瘤容积调强治疗中剂量验证的影响
- Effects of secondary interlocking on the dose verification of head tumor in the treatment of volumetric modulated arc therapy
- 辐射研究与辐射工艺学报 2016年34卷第2期页码：20202
- 作者机构：
  
  1.天津大学精密仪器与光电子工程学院天津 300072;
  2.武警后勤学院附属医院放疗中心天津 300162;
  3.武警后勤学院人体解剖与组织胚胎学教研室天津 300309
- 作者简介：
  
  孟慧鹏,男,1981年10月出生,2011年于南开大学获得硕士学位,目前为天津大学博士研究生,主要从事肿瘤放射治疗物理学及网络相关的研究工作,物理师、高级工程师,E-mail:hongyi1218@163.com
- 基金信息：
  
  武警后勤学院科研创新团队项目(WHTD201308-2)资助Supported by Project of Scientific Research Innovation Team of Logistics University of CAPF (WHTD201308-2)
- DOI：10.11889/j.1000-3436.2016.rrj.34.020202
  中图分类号：
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孟慧鹏, 董化江, 孙小喆, 等. 次要联锁对头部肿瘤容积调强治疗中剂量验证的影响[J]. 辐射研究与辐射工艺学报, 2016,34(2):20202.

Huipeng MENG, Huajiang DONG, Xiaozhe SUN, et al. Effects of secondary interlocking on the dose verification of head tumor in the treatment of volumetric modulated arc therapy[J]. Journal of Radiation Research and Radiation Processing, 2016,34(2):20202.
孟慧鹏, 董化江, 孙小喆, 等. 次要联锁对头部肿瘤容积调强治疗中剂量验证的影响[J]. 辐射研究与辐射工艺学报, 2016,34(2):20202. DOI： 10.11889/j.1000-3436.2016.rrj.34.020202.

Huipeng MENG, Huajiang DONG, Xiaozhe SUN, et al. Effects of secondary interlocking on the dose verification of head tumor in the treatment of volumetric modulated arc therapy[J]. Journal of Radiation Research and Radiation Processing, 2016,34(2):20202. DOI： 10.11889/j.1000-3436.2016.rrj.34.020202.

摘要

随机选取50例头部肿瘤患者的验证计划,采用PTW电离室矩阵进行验证,以1%/1 mm、2%/2 mm和3%/3 mm 3种标准进行g通过率分析。3种标准各5组验证结果的g通过率(验证时人为随机中断1次、2次、3次、4次、5次)与正常验证的结果行配对T检验分析。分析发现3种标准各5组配对检验结果的g通过率均有统计学差异(,t,值12.647~62.911,p,<,0.001)。结果提示,次要联锁发生时继续进行剂量验证对g通过率有明显影响,建议头部肿瘤放疗中次要联锁频繁发生时应停机排除故障后再治疗。

Abstract

The data of dose verification for head tumor in the treatment of volumetric modulated arc therapy (VMAT) was compared to analyze whether or not the statistics difference of gamma passing rates exists when the secondary interlocking occurs. The verification planned for head tumor of 50 patients were used for testing and verifying with the chamber array detector from PTW(PTW Detector 729). Five comparative experiments were performed for each pair of the three standards. The gamma passing rate of 1%/1 mm, 2%/2 mm, 3%/3 mm and T-test were used in the quantitative analysis. Statistical differences were found for all measurements of the three standards paired groups (,t, value range: 12.647~62.911,p,<,0.001). The comparative analysis showed that the gamma passing rates was affected significantly when the secondary interlocking occurred. It is suggested that the treatment should be stopped until troubleshooting when the secondary interlocking occurred frequently in the radiotherapy.

关键词

次要联锁头部肿瘤容积调强通过率

Keywords

Secondary interlockingHead tumorVolumetric modulated arc therapy(VMAT)Pass rate

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