1.北京协和医学院&中国医学科学院放射医学研究所天津市放射医学与分子核医学重点实验室 天津 300192
[ "张欣,女,1990年11月出生,2014年毕业于潍坊医学院,现为北京协和医学院在读硕士研究生,公共卫生专业,E-mail:13146513785@163.com", "ZHANG Xin (female) was born in November 1990 and graduated from Weifang Medical College in 2014. Now she is amaster candidate in Peking Union Medical College, majoring in public health. E-mail:13146513785@163.com" ]
赵永成,研究员,E-mail:zhaoyc60@irm-cams.ac.cn ZHAO Yongcheng, professor, E-mail:zhaoyc60@irm-cams.ac.cn
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张欣, 孙志娟, 赵永成. 长期低剂量电离辐射对工作人员心电图影响的Meta分析[J]. 辐射研究与辐射工艺学报, 2016,34(4):27-31.
Xin ZHANG, Zhijuan SUN, Yongcheng ZHAO. Meta-analysis of the effect of low dose ionizing radiation on ECGs of radiation workers[J]. Journal of Radiation Research and Radiation Processing, 2016,34(4):27-31.
张欣, 孙志娟, 赵永成. 长期低剂量电离辐射对工作人员心电图影响的Meta分析[J]. 辐射研究与辐射工艺学报, 2016,34(4):27-31. DOI: 10.11889/j.1000-3436.2016.rrj.34.040202.
Xin ZHANG, Zhijuan SUN, Yongcheng ZHAO. Meta-analysis of the effect of low dose ionizing radiation on ECGs of radiation workers[J]. Journal of Radiation Research and Radiation Processing, 2016,34(4):27-31. DOI: 10.11889/j.1000-3436.2016.rrj.34.040202.
通过搜索有关文献,按照预先设定的纳入排除标准严格筛选后,以放射组和对照组心电图检查总人数、心电图异常人数为基本数据,研究其异质性检验,用,OR,(,OR,即比值比,表示暴露者的疾病危险性与非暴露者疾病危险性的比值)作为效应值,然后使用固定效应模型或随机效应模型进行Meta分析。结果显示,符合纳入标准的文献共计15篇;放射组与对照组之间异常率有统计学意义[,OR,=1.63,95% CI (1.32,2.02),,p,<,0.00001]。结果提示,长期暴露于低剂量电离辐射环境下会对工作人员心电图异常有显著影响。
According to predefined inclusion and exclusion criteria, the relevant literatures were searched and qualified literatures were determined. Based on total number of electrocardiogram (ECG) examination and number of abnormal ECG in radiation group and control group, the heterogeneity test was employed by using effect size of ,OR, (,OR, is odd ratio, it represents the ratio of exposure to disease risk and non-exposure to disease risk). Fixed effect model or random effect model was used for meta analysis. A total of 15 literatures met the inclusion criteria. Meta-analyses showed that the difference on ECG abnormality rate between the radiation group and the control group was statistical significant[,OR,=1.63, 95% CI (1.32, 2.02),p,<,0.00001]. It suggests that long term exposure to professionally low dose-ionizing radiation has significant influence on ECG abnormality risk in radiation workers.
电离辐射心电图异常率Meta分析
Ionizing radiationElectrocardiogram (ECG)Abnormal rateMeta-analysis
Higgins J P T, Green S C. Handbook for Systematic Reviews of Interventions Version 5.1.0[M/OL] [2011-3-15].[2016-6-15]. The Cochrane Collaboration, 2011. https://www.cochrane-handbook.orghttps://www.cochrane-handbook.org.
颜 玲 , 郑 文华 , 任 德和 . 济南市609名放射工作人员健康状况调查 . 中国辐射卫生 , 2012 . 21 (4 ):431 -432 . DOI:10.13491/j.cnki.issn.1004-714x.2012.04.043http://doi.org/10.13491/j.cnki.issn.1004-714x.2012.04.043 .
Ling YAN , Wenhua ZHENG , Dehe REN . 609 radiation workers' health survey in Jinan . Chinese Journal of Radiological Health , 2012 . 21 (4 ):431 -432 . DOI:10.13491/j.cnki.issn.1004-714x.2012.04.043http://doi.org/10.13491/j.cnki.issn.1004-714x.2012.04.043 .
万 红 , 谭 卫国 , 杨 剑 , 等 . 电离辐射对放射工作人员心血管系统的影响 . 中国辐射卫生 , 2013 . 22 (1 ):47 -48 . DOI:10.13491/j.cnki.issn.1004-714x.2013.01.028http://doi.org/10.13491/j.cnki.issn.1004-714x.2013.01.028 .
Hong WAN , Weiguo TAN , Jian YANG , 等 . The effect of ionizing radiation on radiation workers in the cardiovascular system . Chinese Journal of Radiological Health , 2013 . 22 (1 ):47 -48 . DOI:10.13491/j.cnki.issn.1004-714x.2013.01.028http://doi.org/10.13491/j.cnki.issn.1004-714x.2013.01.028 .
周 玲玲 , 姚 耿东 , 王 金富 . 台州市医用X线诊断工作者健康状况调查 . 浙江预防医学 , 2003 . 15 (2 ):26 -27 . http://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX200302015.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX200302015.htm, .
Lingling ZHOU , Gengdong YAO , Jinfu WANG . The health survey of taizhou medical x-ray diagnosis workers . Zhejiang Journal of Preventive Medicine , 2003 . 15 (2 ):26 -27 . http://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX200302015.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-ZYFX200302015.htm, .
蒋 文 , 朱 冬梅 , 方 新立 . 周口市2006-2009年放射工作人员健康体检结果分析 . 职业与健康 , 2010 . 26 (20 ):2309 -2311 . DOI:10.13329/j.cnki.zyyjk.2010.20.007http://doi.org/10.13329/j.cnki.zyyjk.2010.20.007 .
Wen JIANG , Dongmei ZHU , Xinli FANG . Healthy analysis of Zhoukou radiation workers in 2006——2009 . Occupation and Health , 2010 . 26 (20 ):2309 -2311 . DOI:10.13329/j.cnki.zyyjk.2010.20.007http://doi.org/10.13329/j.cnki.zyyjk.2010.20.007 .
周 亮 , 张 红伟 , 张 志旭 . 北京市顺义区202名放射工作人员健康调查结果 . 职业与健康 , 2011 . 27 (14 ):1611 -1613 . DOI:10.13329/j.cnki.zyyjk.2011.14.006http://doi.org/10.13329/j.cnki.zyyjk.2011.14.006 .
Liang ZHOU , Hongwei ZHANG , Zhixu ZHANG . Investigation on physical condition of 202 radiation workers in Shunyi District of Beijing city . Occupation and Health , 2011 . 27 (14 ):1611 -1613 . DOI:10.13329/j.cnki.zyyjk.2011.14.006http://doi.org/10.13329/j.cnki.zyyjk.2011.14.006 .
曹 立荣 , 郭 美艳 , 杜 冉 . 272名放射工作人员职业健康检查结果的分析 . 中华劳动卫生职业病杂志 , 2012 . 30 (8 ):634 -635. .
Lirong CAO , Meiyan GUO , Ran DU . Occupational health examination results analysis of 272 radiation workers . Journal of Occupational Health , 2012 . 30 (8 ):634 -635. .
张 霞 , 张 燕 , 张 从容 , 等 . 2013年沧州市放射工作人员职业健康调查 . 职业与健康 , 2014 . 30 (12 ):1580 -1729 . DOI:10.13329/j.cnki.zyyjk.2014.12.018http://doi.org/10.13329/j.cnki.zyyjk.2014.12.018 .
Xia ZHANG , Yan ZHANG , Congrong ZHANG , 等 . Occupational health survey of radiation workers in cangzhou city in 2013 . Occupation and Health , 2014 . 30 (12 ):1580 -1729 . DOI:10.13329/j.cnki.zyyjk.2014.12.018http://doi.org/10.13329/j.cnki.zyyjk.2014.12.018 .
杨 文草 , 高 晓玲 , 唐 颖 . 上海市144名医用X射线工作人员10年健康动态观察 . 环境与职业医学 , 2011 . 28 (4 ):232 -234 . DOI:10.13213/j.cnki.jeom.2011.04.005http://doi.org/10.13213/j.cnki.jeom.2011.04.005 .
Wencao YANG , Xiaoling GAO , Ying TANG . The 10 years healthy dynamic observation of 144 X-ray medical staff in Shanghai . Environmental and Occupational Medicine , 2011 . 28 (4 ):232 -234 . DOI:10.13213/j.cnki.jeom.2011.04.005http://doi.org/10.13213/j.cnki.jeom.2011.04.005 .
林 朝杰 , 何 祥金 , 刘 军 , 等 . 内江市近五年放射工作人员体检结果分析研究 . 中国辐射卫生 , 2004 . 13 (1 ):61 DOI:10.13491/j.cnki.issn.1004-714x.2004.01.048http://doi.org/10.13491/j.cnki.issn.1004-714x.2004.01.048 .
Chaojie LIN , Xiangjin HE , Jun LIU , 等 . The nearly 5 years of radiation workers examination results analysis in Neijiang . Chinese Journal of Radiological Health , 2004 . 13 (1 ):61 DOI:10.13491/j.cnki.issn.1004-714x.2004.01.048http://doi.org/10.13491/j.cnki.issn.1004-714x.2004.01.048 .
陈 清洪 , 陈 煜 , 郭 华南 . 龙岩市医用X射线工作人员健康检查现况分析 . 海峡预防医学 , 2009 . 15 (2 ):62 -63 . http://www.cnki.com.cn/Article/CJFDTOTAL-HXYF200902036.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-HXYF200902036.htm, .
Qinghong CHEN , Yu CHEN , Huanan GUO . The health status analysis of Medical X-ray staff in Longyan . Strait Journal Preventive Medicine , 2009 . 15 (2 ):62 -63 . http://www.cnki.com.cn/Article/CJFDTOTAL-HXYF200902036.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-HXYF200902036.htm, .
颜 玲 , 柳 光忠 , 韩 笃菊 . 702名放射工作人员心电图检查结果分析 . 中国辐射卫生 , 2006 . 15 (3 ):324 DOI:10.13491/j.cnki.issn.1004-714x.2006.03.045http://doi.org/10.13491/j.cnki.issn.1004-714x.2006.03.045 .
Ling YAN , Guangzhong LIU , DuJu HAN . The ECG analysis of 702 radiation workers . Chinese Journal of Radiological Health , 2006 . 15 (3 ):324 DOI:10.13491/j.cnki.issn.1004-714x.2006.03.045http://doi.org/10.13491/j.cnki.issn.1004-714x.2006.03.045 .
邹 郁松 , 许 卓再 , 梁 立荣 . 150名放射工作人员职业健康检查结果评价 . 中国病案 , 2015 . 16 (3 ):93 -96 . http://www.cnki.com.cn/Article/CJFDTOTAL-ZGBN201503037.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-ZGBN201503037.htm, .
Yusong ZOU , Zhuozai XU , Lirong LIANG . The occupational health examination results evaluation of 150 radiation workers . Chinese Medical Record , 2015 . 16 (3 ):93 -96 . http://www.cnki.com.cn/Article/CJFDTOTAL-ZGBN201503037.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-ZGBN201503037.htm, .
张 凤珍 . 717例放射工作人员心电图异常情况调查 . 预防医学文献信息 , 2001 . 7 (3 ):267 http://www.cnki.com.cn/Article/CJFDTOTAL-YXWX200103030.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-YXWX200103030.htm, .
Fengzhen ZHANG . Investigation of 717 radiologists ECG abnormalities . Information on Preventive Medicine , 2001 . 7 (3 ):267 http://www.cnki.com.cn/Article/CJFDTOTAL-YXWX200103030.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-YXWX200103030.htm, .
李 建华 , 何 伟 , 王 林超 . 某钢铁企业342名放射工作人员健康状况调查 . 中国辐射卫生 , 2008 . 17 (3 ):313 -314 . DOI:10.13491/j.cnki.issn.1004-714x.2008.03.028http://doi.org/10.13491/j.cnki.issn.1004-714x.2008.03.028 .
Jianhua LI , Wei HE , Linchao WANG . 342 Radiation workers' health survey in certain iron and steel enterprises . Chinese Journal of Radiological Health , 2008 . 17 (3 ):313 -314 . DOI:10.13491/j.cnki.issn.1004-714x.2008.03.028http://doi.org/10.13491/j.cnki.issn.1004-714x.2008.03.028 .
罗 文文 , 赵 洁 . 消化内科医生放射暴露情况调查及健康状况分析 . 中华劳动卫生职业病杂志 , 2014 . 32 (2 ):133 -135. .
Wenwen LUO , Jie ZHAO . Investigation of digestion physician radiation exposure and health status . Chinese Journal of Industrial Hygiene and Occupational Diseases , 2014 . 32 (2 ):133 -135. .
M Hauptmann , A K Mohan , M M Doody , 等 . Mortality from diseases of the circulatory system in radiologic technologists in the United States . American Journal of Epidemiology , 2003 . 157 239 -248 . DOI:10.1093/aje/kwf189http://doi.org/10.1093/aje/kwf189.
C R Muirhead , J A O'Hagan , R G Haylock , 等 . Mortality and cancer incidence following occupational radiation exposure:third analysis of the national registry for radiation workers . British Journal of Cancer , 2009 . 100 206 -212 . DOI:10.1038/sj.bjc.6604825http://doi.org/10.1038/sj.bjc.6604825.
娄 淑艳 . 放射从业人员心电图分析 . 职业医学 , 1998 . 25 (3 ):52 -53 . http://www.cnki.com.cn/Article/CJFDTOTAL-XYYX803.025.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-XYYX803.025.htm, .
Shuyan LOU . Electrocardiogram analysis of radiation workers . Occupational medicine , 1998 . 25 (3 ):52 -53 . http://www.cnki.com.cn/Article/CJFDTOTAL-XYYX803.025.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-XYYX803.025.htm, .
陈 艾东 , 李 娟 , 谢 海棠 . 内皮素心血管效应的研究进展 . 中国临床药理学与治疗学 , 2011 . 16 (8 ):937 -944 . http://www.cnki.com.cn/Article/CJFDTOTAL-YLZL201108029.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-YLZL201108029.htm, .
Aidong CHEN , Juan LI , Haitang XIE . Recent research progress in cardiovascular effects of endothelin . Chinese Journal of Clinical Pharmacology and Therapeutics , 2011 . 16 (8 ):937 -944 . http://www.cnki.com.cn/Article/CJFDTOTAL-YLZL201108029.htmhttp://www.cnki.com.cn/Article/CJFDTOTAL-YLZL201108029.htm, .
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