磁性铁纳米材料的细胞学效应和膜转运机制

王璐; 相法伟; 韩玉萍; 汪婷; 王坤; 王文锋; 陈楠

doi:10.11889/j.1000-3436.2016.rrj.34.050101

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磁性铁纳米材料的细胞学效应和膜转运机制

综述 | 更新时间：2021-12-10

- 磁性铁纳米材料的细胞学效应和膜转运机制
- Cellular effects and membrane trafficking of magnetic iron nanoparticles
- 辐射研究与辐射工艺学报 2016年34卷第5期
- 作者机构：
  
  1.中国科学院上海应用物理研究所物理生物学成像中心上海同步成像光源张江园区上海 201204
  2.中国科学院大学北京 100049
  3.潍坊市人民医院放射科潍坊 261000
  4.四川大学生命科学学院成都 610064
- 作者简介：
  
  [ "王璐, 女, 1988年6月出生, 2013年于四川大学获硕士学位, 现为中国科学院上海应用物理研究所博士研究生, 研究领域为纳米生物学, E-mail:lwangsinap@163.com", "WANG Lu (female) was born in June 1988 and received her master degree from Sichuan University in 2013. Now she is a doctor candidate in Shanghai Institute of Applied Physics, Chinese Academy of Sciences, majoring in nanobiology. E-mail:lwangsinap@163.com" ]
  陈楠, 博士, 研究员, E-mail:chennan@sinap.ac.cnPh.D. CHEN Nan, professor, E-mail:chennan@sinap.ac.cn
- 基金信息：
  
  国家重大科学研究计划(U1332119);国家重大科学研究计划(31371015);国家重大科学研究计划(31470970)
- DOI：10.11889/j.1000-3436.2016.rrj.34.050101
  中图分类号：
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王璐, 相法伟, 韩玉萍, 等. 磁性铁纳米材料的细胞学效应和膜转运机制[J]. 辐射研究与辐射工艺学报, 2016,34(5):050101-11.

Lu WANG, Fawei XIANG, Yuping HAN, et al. Cellular effects and membrane trafficking of magnetic iron nanoparticles[J]. Journal of Radiation Research and Radiation Processing, 2016,34(5):050101-11.
王璐, 相法伟, 韩玉萍, 等. 磁性铁纳米材料的细胞学效应和膜转运机制[J]. 辐射研究与辐射工艺学报, 2016,34(5):050101-11. DOI： 10.11889/j.1000-3436.2016.rrj.34.050101.

Lu WANG, Fawei XIANG, Yuping HAN, et al. Cellular effects and membrane trafficking of magnetic iron nanoparticles[J]. Journal of Radiation Research and Radiation Processing, 2016,34(5):050101-11. DOI： 10.11889/j.1000-3436.2016.rrj.34.050101.

摘要

总结和讨论了针对Fe,3,O,4,纳米颗粒的生物兼容性、细胞内吞和转运过程及其自身酶活性对自噬和细胞代谢的研究，对于磁性纳米材料在体内抗氧化、自噬调控、疾病和辐射治疗等相关研究具有重要的参考和启发意义。

Abstract

Research progress on biocompatibility, endocytosis and intracellular trafficking, as well as their intrinsic enzymatic activity-related cellular effects of magnetic iron nanoparticles (Fe,3,O,4, NPs) were summarized. These comprehensive researches provide valuable insights for anti-oxidation, autophagy regulation, theranostics, radiation treatment and other biomedical applications of magnetic iron nanoparticles.

关键词

磁性铁纳米材料Fe3O4纳米颗粒模拟酶效应自噬细胞内吞

Keywords

Magnetic iron nanoparticlesFe3O4 NPsEnzyme-like activityAutophagyEndocytosis

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