外泌体定量检测的研究进展及其在疾病诊疗中的应用

苏静; 宋世平

doi:10.11889/j.1000-3436.2017.rrj.35.030101

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外泌体定量检测的研究进展及其在疾病诊疗中的应用

综述 | 更新时间：2021-12-10

- 外泌体定量检测的研究进展及其在疾病诊疗中的应用
- A review of the quantitative detection and diagnostic and therapeutic applications of exosomes
- 辐射研究与辐射工艺学报 2017年35卷第3期
- 作者机构：
  
  1.中国科学院上海应用物理研究所嘉定园区上海 201800
- 作者简介：
  
  [ "苏静, 女, 1990年10月出生, 2017年6月于中国科学院上海应用物理研究所获理学博士学位, 无机化学专业, E-mail:wo_shisujing@126.com", "SU Jing (female) was born in October 1990 and received her doctor's degree from Shanghai Institute of Applied Physics, Chinese Academy of Sciences in June 2017, majoring in inorganic chemistry, E-mail:wo_shisujing@126.com" ]
  宋世平, 博士, 研究员, E-mail:spsong@sinap.ac.cn Ph.D. SONG Shiping, professor, E-mail:spsong@sinap.ac.cn
- 基金信息：
  
  国家重大科学研究计划(2013CB932800);国家自然科学基金(21373260);国家自然科学基金(31571014)
- DOI：10.11889/j.1000-3436.2017.rrj.35.030101
  中图分类号：
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苏静, 宋世平. 外泌体定量检测的研究进展及其在疾病诊疗中的应用[J]. 辐射研究与辐射工艺学报, 2017,35(3):030101-10.

Jing SU, Shiping SONG. A review of the quantitative detection and diagnostic and therapeutic applications of exosomes[J]. Journal of Radiation Research and Radiation Processing, 2017,35(3):030101-10.
苏静, 宋世平. 外泌体定量检测的研究进展及其在疾病诊疗中的应用[J]. 辐射研究与辐射工艺学报, 2017,35(3):030101-10. DOI： 10.11889/j.1000-3436.2017.rrj.35.030101.

Jing SU, Shiping SONG. A review of the quantitative detection and diagnostic and therapeutic applications of exosomes[J]. Journal of Radiation Research and Radiation Processing, 2017,35(3):030101-10. DOI： 10.11889/j.1000-3436.2017.rrj.35.030101.

摘要

对外泌体的生物起源以及近几年报道的利用物理方法、电化学、表面等离子共振以及微流控等外泌体定量的方法进行了综述，并对外泌体在疾病诊疗中的应用包括外泌体作为潜在的肿瘤标志物以及辐射诱导的外泌体的生物学效应进行综述，最后对外泌体研究的未来发展进行了展望。

Abstract

This review outlines the biogenesis of exosomes and quantitative methods for exosome detection that have emerged in recent years, including surface plasmon resonance and physical, electrochemical, and microfluidic methods. The applications of exosomes in the diagnosis and treatment of diseases, such as the screening of exosomes as potential tumor markers and the biological effects of radiation-induced exosomes, are summarized. Moreover, future trends in exosome research are forecasted.

关键词

外泌体定量检测生物标志物诊疗辐射综述

Keywords

ExosomesQuantitative determinationBiomarkerDiagnosis and treatmentRadiationReview

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