染料木黄酮在放射损伤防护中的研究进展

逄志骏; 何磊; 周继明; 马晓雯; 张旭涛; 王昭维; 李萌

doi:10.11889/j.1000-3436.2018.rrj.36.050101

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染料木黄酮在放射损伤防护中的研究进展

综述 | 更新时间：2021-12-10

- 染料木黄酮在放射损伤防护中的研究进展
- A review of the protective effects of genistein against radiation injuries
- 辐射研究与辐射工艺学报 2018年36卷第5期
- 作者机构：
  
  1.第四军医大学药学系生物制药学教研室西安 710032
  2.解放军第四〇一医院检验科青岛 266000
- 作者简介：
  
  [ "逄志骏, 男, 1990年5月出生, 2012年6月于第二军医大学获理学学士学位, 现为第四军医大学药学系硕士研究生, 研究方向为生物化学与分子生物学, E-mail: bigpie@yeah.net", "PANG Zhijun (male) was born in May 1990, and obtained his bachelor's degree from The Second Military Medical University in June 2012. Now he is a master candidate in the Department of Pharmacy of The Fourth Military Medical University, majoring in biochemistry and molecular biology. E-mail: bigpie@yeah.net" ]
  李萌, 博士, 副教授, E-mail: limeng@fmmu.edu.cn Ph.D. LI Meng, associate professor, E-mail: limeng@fmmu.edu.cn
- 基金信息：
  
  国家自然科学基金项目(81673020)
- DOI：10.11889/j.1000-3436.2018.rrj.36.050101
  中图分类号：
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逄志骏, 何磊, 周继明, 等. 染料木黄酮在放射损伤防护中的研究进展[J]. 辐射研究与辐射工艺学报, 2018,36(5):050101-6.

Zhijun PANG, Lei HE, Jiming ZHOU, et al. A review of the protective effects of genistein against radiation injuries[J]. Journal of Radiation Research and Radiation Processing, 2018,36(5):050101-6.
逄志骏, 何磊, 周继明, 等. 染料木黄酮在放射损伤防护中的研究进展[J]. 辐射研究与辐射工艺学报, 2018,36(5):050101-6. DOI： 10.11889/j.1000-3436.2018.rrj.36.050101.

Zhijun PANG, Lei HE, Jiming ZHOU, et al. A review of the protective effects of genistein against radiation injuries[J]. Journal of Radiation Research and Radiation Processing, 2018,36(5):050101-6. DOI： 10.11889/j.1000-3436.2018.rrj.36.050101.

摘要

随着核事故的增加和未来战争形势的需要，各国日益重视放射损伤引发的危害，对放射损伤保护药物的研究也从未止步。放射损伤保护药物能够减少电离辐射导致的细胞或机体损伤，在放射防护体系中发挥重要作用。天然活性成分染料木黄酮由于其较强的抗放射性及低毒副作用，成为了抗放射药物的研究热点，美国对其在军事放射损伤防护方面的研究已进入临床试验阶段。本文综述了近年来染料木黄酮的抗放射研究进展。

Abstract

In recent years, with the increase of nuclear accidents and the possible need for future war, countries are paying increased attention to the harm caused by radiation injury, and research on drugs that can offer radiation protection is ongoing. Anti-radiation drugs can reduce cell or body damage caused by ionizing radiation and play an important role in radiation protection system. Genistein, a natural active component, has become a hotspot in the research of anti-radiation drugs because of its strong anti-radioactivity and fewer toxic side effects. The research on military radiation injury in the United States has reached the clinical trial stage. In this paper, the recent advances with respect to radioprotective activities of genistein are reviewed.

关键词

辐射损伤染料木黄酮辐射防护剂综述

Keywords

Radiation injuriesGenisteinRadiation-protective agentsReview

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