1.空军军医大学军事预防医学系辐射防护医学教研室 特殊作业环境危害评估与防治教育部重点实验室 西安 710032
2.陕西中医药大学公共卫生学院 咸阳 712000
郭娟,女,1984年8月出生,2012年于空军军医大学获博士学位,讲师,主要从事辐射生物学研究
林加金,讲师,E-mail: linjiajin913@126.com
扫 描 看 全 文
郭娟, 杜丹, 李静, 等. 邻近布局引起实验动物电磁剂量变化的仿真[J]. 辐射研究与辐射工艺学报, 2023,41(5):050702.
GUO Juan, DU Dan, LI Jing, et al. Simulations of neighboring-layout-induced electromagnetic dose variations in experimental animals[J]. Journal of Radiation Research and Radiation Processing, 2023,41(5):050702.
郭娟, 杜丹, 李静, 等. 邻近布局引起实验动物电磁剂量变化的仿真[J]. 辐射研究与辐射工艺学报, 2023,41(5):050702. DOI: 10.11889/j.1000-3436.2023-0009.
GUO Juan, DU Dan, LI Jing, et al. Simulations of neighboring-layout-induced electromagnetic dose variations in experimental animals[J]. Journal of Radiation Research and Radiation Processing, 2023,41(5):050702. DOI: 10.11889/j.1000-3436.2023-0009.
针对多频点、大样本量生物电磁暴露系统中剂量差异特征不明确的问题,采用生物电磁仿真软件Sim4Life建立了4种对比仿真环境,仿真频率点为1.8 GHz、2.4 GHz、3.6 GHz和5.8 GHz,对实验小鼠的散射电场和全身平均比吸收率(Whole body average specific absorption ratio,WBASAR)进行了仿真计算及分析。结果表明:受到电磁散射的影响,邻近布局中实验动物的WBASAR值随空间分布变化,变化规律与激励电场的分布趋势相似;激励电场是引起WBASAR值变化的主要因素。此外,WBASAR值的变化还受到频率的影响,高“身体尺寸-波长”比值抑制WBASAR值的变化。针对实验动物的电磁剂量变化特征,提出了降低群体剂量不确定性的设计建议。本研究为生物电磁实验平台的设计提供了剂量评估基础。
In this study, the issues of unclear characteristics of dose differences in multi-frequency and large-sample bioelectromagnetic exposure systems were studied. For this, four contrast simulation environments were established using Sim4Life. The frequency points in the simulation were set to 1.8, 2.4, 3.6, and 5.8 GHz, respectively. The scattering field and whole-body average specific absorption rate (WBASAR) values were simulated and analyzed. The results revealed that the WBASAR value for experimental animals was influenced by the electromagnetic scattering of adjacent animals, and the spatial distribution of the WBASAR value was similar to the trend followed by the excitation field distribution. The excitation field was the primary factor causing the variation in the WBASAR distribution. In addition, the WBASAR distribution varies with frequency, and a higher ratio of body size to wavelength inhibits the WBASAR variation. Furthermore, a design suggestion for the exposed platform was proposed to reduce group dose uncertainty based on the variation characteristics. Overall, this study provides a dose evaluation basis for the design of electromagnetic exposure systems.
邻近布局变化全身平均比吸收率剂量电磁辐射
Neighboring layoutVariationWhole body average specific absorption ratio(WBASAR)DoseElectromagnetic radiation
苏镇涛, 杨国山. 高功率脉冲微波照射时大鼠体内SAR值计算[J]. 中华放射医学与防护杂志, 2004, 24(6): 561-563. DOI: 10.3760/cma.j.issn.0254-5098.2004.06.030http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2004.06.030.
SU Zhentao, YANG Guoshan. Calculation of SAR in rats exposed to pulsed high power microwave irradiation[J]. Chinese Journal of Radiation Mediation and Protection, 2004, 24(6): 561-563. DOI: 10.3760/cma.j.issn.0254-5098.2004.06.030http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2004.06.030.
苏镇涛, 周红梅, 罗霞, 等. 微波暴露下实验用鼠体重与电磁能量吸收关系研究[J]. 中华放射医学与防护杂志, 2008, 28(3): 301-303.. DOI: 10.3760/cma.j.issn.0254-5098.2008.03.034http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2008.03.034.
SU Zhentao, ZHOU Hongmei, LUO Xia, et al. The EM energy absorption in different rat model exposed to microwave irradiation[J]. Chinese Journal of Radiological Medicine and Protection, 2008, 28(3): 301-303. DOI: 10.3760/cma.j.issn.0254-5098.2008.03.034http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2008.03.034.
彭怀禹, 李孟达, 齐红新, 等. 双波源同向交替入射下大鼠的电磁暴露仿真[J]. 辐射研究与辐射工艺学报, 2021, 39(5): 050303. DOI: 10.11889/j.1000-3436.2021.rrj. 39.050303http://dx.doi.org/10.11889/j.1000-3436.2021.rrj.39.050303.
PENG Huaiyu, LI Mengda, QI Hongxin, et al. Numerical simulation of electromagnetic exposure in rats with alternate incidence of double wave sources[J]. Journal of Radiation Research and Radiation Processing, 2021, 39(5): 050303. DOI: 10.11889/j.1000-3436.2021.rrj.39. 050303http://dx.doi.org/10.11889/j.1000-3436.2021.rrj.39.050303.
周兢程, 林艳云, 陈克亮, 等. 射频电磁辐射对大鼠脑组织胆碱能标志物的影响[J]. 辐射研究与辐射工艺学报, 2017, 35(1): 010202. DOI: 10.11889/j.1000-3436.2017.rrj. 35.010202http://dx.doi.org/10.11889/j.1000-3436.2017.rrj.35.010202.
ZHOU Jingcheng, LIN Yanyun, CHEN Keliang, et al. Effects of radiation-frequency electromagnetic radiation on cholinergic neuronal markers of SD rat brain[J]. Journal of Radiation Research and Radiation Processing, 2017, 35(1): 010202. DOI: 10.11889/j.1000-3436.2017.rrj. 35.010202http://dx.doi.org/10.11889/j.1000-3436.2017.rrj.35.010202.
芮刚, 刘力源, 林加金, 等. 5.8 GHz射频辐射对大鼠学习记忆和海马神经元突触可塑性的影响[J]. 中华放射医学与防护杂志, 2020, 40(6): 427-433.. DOI: 10.3760/cma.j.issn.0254-5098.2020.06.003http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2020.06.003.
RUI Gang, LIU Liyuan, LIN Jiajin, et al. Effects of 5.8 GHz radiofrequency radiation on learning and memory along with synaptic plasticity of hippocampal neurons in rats[J]. Chinese Journal of Radiological Medicine and Protection, 2020, 40(6): 427-433. DOI: 10.3760/cma.j.issn.0254-5098.2020.06.003http://dx.doi.org/10.3760/cma.j.issn.0254-5098.2020.06.003.
王海彬, 牛中奇. 人体对电磁脉冲吸收剂量的仿真研究[J]. 电波科学学报, 2006, 21(2): 259-264. DOI: 10. 13443/j.cjors.2006.02.021http://dx.doi.org/10.13443/j.cjors.2006.02.021.
WANG Haibin, NIU Zhongqi. Specific absorption and currents induced in human body for exposure to electromagnetic pulses[J]. Chinese Journal of Radio Science, 2006, 21(2): 259-264. DOI: 10.13443/j.cjors. 2006.02.021http://dx.doi.org/10.13443/j.cjors.2006.02.021.
牛中奇, 侯建强, 周永军, 等. 生物电磁剂量学及人体吸收电磁剂量的数值分析[J]. 中国生物医学工程学报, 2006, 25(5): 580-584. DOI: 10.3969/j.issn.0258-8021. 2006.05.014http://dx.doi.org/10.3969/j.issn.0258-8021.2006.05.014.
NIU Zhongqi, HOU Jianqiang, ZHOU Yongjun, et al. The bioelectromagnetics dosimetry and numerical analysis of electromagnetic dose absorbed by human body[J]. Chinese Journal of Biomedical Engineering, 2006, 25(5): 580-584. DOI: 10.3969/j.issn.0258-8021.2006. 05.014http://dx.doi.org/10.3969/j.issn.0258-8021.2006.05.014.
朱士虎, 卢智远, 孔令锋. 稳态平面波作用下人体比吸收率分布研究[J]. 山东生物医学工程, 2003, 22(2): 25-27. DOI: 10.19529/j.cnki.1672-6278.2003.02.008http://dx.doi.org/10.19529/j.cnki.1672-6278.2003.02.008.
ZHU Shihu, LU Zhiyuan, KONG Lingfeng. Study on the distribution of specific absorption rates(SAR) in human body effected by stable plane wave[J]. Shandong Journal of Biomedical Engineering, 2003, 22(2): 25-27. DOI: 10. 19529/j.cnki.1672-6278.2003.02.008http://dx.doi.org/10.19529/j.cnki.1672-6278.2003.02.008.
玉冬. 中国参考人可变形模型构建方法及电磁辐射剂量研究[D]. 武汉: 华中科技大学, 2015.
YU Dong. Construction method of deformable model of China reference person and study on electromagnetic radiation dose[D].Wuhan: Huazhong University of Science and Technology, 2015.
王萌. 生物电磁学仿真框架构建及儿童可变形模型的电磁辐射模拟应用[D]. 武汉: 华中科技大学, 2019. 10.17485/ijst/2019/v12i23/143825http://dx.doi.org/10.17485/ijst/2019/v12i23/143825
WANG Meng. Development of bioelectromagnetic simulation framework and electromagnetic radiation simulation application based on children deformable phantom[D]. Wuhan: Huazhong University of Science and Technology, 2019. 10.17485/ijst/2019/v12i23/143825http://dx.doi.org/10.17485/ijst/2019/v12i23/143825
Kuster N, Torres V B, Nikoloski N, et al. Methodology of detailed dosimetry and treatment of uncertainty and variations for in vivo studies[J]. Bioelectromagnetics, 2006, 27(5): 378-391. DOI: 10.1002/bem.20219http://dx.doi.org/10.1002/bem.20219.
孙艺宸, 杜丹, 李静, 等. 实验动物体重差异引起的电磁剂量差异和不确定性[J]. 辐射研究与辐射工艺学报, 2023, 41(1): 010302. DOI: 10.11889/j.1000-3436.2022-0115http://dx.doi.org/10.11889/j.1000-3436.2022-0115.
SUN Yichen, DU Dan, LI Jing, et al. Variations and uncertainty in electromagnetic dose caused by weight differences of experimental animals[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(1): 010302. DOI: 10.11889/j.1000-3436.2022-0115http://dx.doi.org/10.11889/j.1000-3436.2022-0115.
Paffi A, Apollonio F, Lovisolo G A, et al. Considerations for developing an RF exposure system: a review for in vitro biological experiments[J]. IEEE Transactions on Microwave Theory and Techniques, 2010, 58(10): 2702-2714. DOI: 10.1109/TMTT.2010.2065351http://dx.doi.org/10.1109/TMTT.2010.2065351.
袁梦, 林艳云, 郭奇彦, 等. 1 840 MHz电磁辐射对雄性SD大鼠性激素的影响及其抗氧化损伤作用研究[J]. 现代生物医学进展, 2017, 17(28): 5406-5411. DOI: 10. 13241/j.cnki.pmb.2017.28.002http://dx.doi.org/10.13241/j.cnki.pmb.2017.28.002.
YUAN Meng, LIN Yanyun, GUO Qiyan, et al. Effects of 1 840 MHz radiation-frequency electromagnetic radiation on the sex hormone secretion of male SD rats and its anti-oxidative damage effect[J]. Progress in Modern Biomedicine, 2017, 17(28): 5406-5411. DOI: 10.13241/j.cnki.pmb.2017.28.002http://dx.doi.org/10.13241/j.cnki.pmb.2017.28.002.
Wu T N, Hadjem A, Wong M F, et al. Whole-body new-born and young rats' exposure assessment in a reverberating chamber operating at 2.4 GHz[J]. Physics in Medicine and Biology, 2010, 55(6): 1619-1630. DOI: 10.1088/0031-9155/55/6/006http://dx.doi.org/10.1088/0031-9155/55/6/006.
Wang X H, Xia C J, Lu L, et al. Electromagnetic exposure dosimetry study on two free rats at 1.8 GHz via numerical simulation[J]. Frontiers in Public Health, 2021, 9: 721166. DOI: 10.3389/fpubh.2021.721166http://dx.doi.org/10.3389/fpubh.2021.721166.
Hirata A, Diao Y L, Onishi T, et al. Assessment of human exposure to electromagnetic fields: review and future directions[J]. IEEE Transactions on Electromagnetic Compatibility, 2021, 63(5): 1619-1630. DOI: 10.1109/TEMC.2021.3109249http://dx.doi.org/10.1109/TEMC.2021.3109249.
赵雪龙, 王长振, 周红梅, 等. P-X频段微波暴露人体比吸收率(SAR)仿真研究[J]. 微波学报, 2020, 36(S1): 420-423.
ZHAO Xuelong, WANG Changzhen, ZHOU Hongmei, et al. Simulation on specific absorption rate(SAR) of human body exposed to P-X band microwave[J]. Journal of Microwaves, 2020, 36(S1): 420-423.
李从胜. 准静态场至S波段电磁波与人体耦合典型场景的FDTD研究[D]. 北京: 北京科技大学, 2015.
LI Congsheng. FDTD study on typical scenes of quasi-static field to S-band electromagnetic wave coupling with human body[D]. Beijing: Beijing University of Science and Technology, 2015.
Gong Y J, Capstick M, Kuehn S, et al. Life-time dosimetric assessment for mice and rats exposed in reverberation chambers of the 2-year NTP cancer bioassay study on cell phone radiation[J]. IEEE Transactions on Electromagnetic Compatibility, 2017, 59(6): 1798-1808. DOI: 10.1109/TEMC.2017.2665039http://dx.doi.org/10.1109/TEMC.2017.2665039.
Shi J J, Chakarothai J, Wang J Q, et al. Dosimetry and verification for 6-GHz whole-body non-constraint exposure of rats using reverberation chamber[J]. IEICE Transactions on Communications, 2015, E98.B(7): 1164-1172. DOI: 10.1587/transcom.e98.b.1164http://dx.doi.org/10.1587/transcom.e98.b.1164.
杜丹, 李静, 苗霞, 等. 1~6 GHz射频暴露平台的设计及剂量特征[J]. 辐射研究与辐射工艺学报, 2022, 40(4): 040701. DOI: 10.11889/j.1000-3436.2022-0029http://dx.doi.org/10.11889/j.1000-3436.2022-0029.
DU Dan, LI Jing, MIAO Xia, et al. Design and dose characteristics of 1~6 GHz radio frequency exposure platform[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(4): 040701. DOI: 10.11889/j.1000-3436.2022-0029http://dx.doi.org/10.11889/j.1000-3436.2022-0029.
童嘉锴, 齐红新, 王向晖, 等. 宽频电磁脉冲辐照大鼠体内电场分布的仿真计算[J]. 辐射研究与辐射工艺学报, 2022, 40(2): 020702. DOI: 10.11889/j.1000-3436.2021-0212http://dx.doi.org/10.11889/j.1000-3436.2021-0212.
TONG Jiakai, QI Hongxin, WANG Xianghui, et al. Simulation calculation of electric field distribution in rats irradiated using broadband electromagnetic pulse[J]. Journal of Radiation Research and Radiation Processing, 2022, 40(2): 020702. DOI: 10.11889/j.1000-3436.2021-0212http://dx.doi.org/10.11889/j.1000-3436.2021-0212.
Bailey W H, Bodemann R, Bushberg J, et al. Synopsis of IEEE std C95.1™-2019 “IEEE standard for safety levels with respect to human exposure to electric, magnetic, and electromagnetic fields, 0 hz to 300 GHz”[J]. IEEE Access, 2019, 7: 171346-171356. DOI: 10.1109/ACCESS.2019.2954823http://dx.doi.org/10.1109/ACCESS.2019.2954823.
Conil E, Hadjem A, Gati A, et al. Influence of plane-wave incidence angle on whole body and local exposure at 2 100 MHz[J]. IEEE Transactions on Electromagnetic Compatibility, 2011, 53(1): 48-52. DOI: 10.1109/TEMC. 2010.2061849http://dx.doi.org/10.1109/TEMC.2010.2061849.
0
浏览量
2
下载量
0
CSCD
关联资源
相关文章
相关作者
相关机构