A series of PNIPA/PEG (poly (N-isopropyl acrylamide)/poly (ethylene glycol)) porous intelligent hydrogels, which exhibited appropriate phase transition temperature and fast response behavior, were synthesized by radiation polymerization with NIPA (N-isopropyl acrylamide) as monomer, PEG (poly (ethylene glycol)) as pore-forming agent and MBA (N, N-methylene-bis-acrylamide) as crosslinking agent. The surface morphology of the material was examined by the scanning electron microscopy. The influences of NIPA content and PEG molecular weight on swelling properties were discussed. Drug release properties were studied with aspirin as a model drug. The results showed that macropores were observed in the sample, whereas hydrogels prepared without using PEG had a dense surface. The swelling ratio and water loss ratio of the sample decreased with increment of NIPA content. LCST (Lower critical solution temperature) and the release ratio increased with PEG molecular weight. The release ratio of PNIPA/PEG6000 hydrogel at 37℃ was larger than that at 25℃ and the release mechanism could be described with Fickian diffusion type.Cited