PAN Xiaosong, SHI Yujia, YAO Yimin, et al. Progress of research on activation function of NK cell exposed to low dose radiation in adoptive cellular immunotherapy[J]. Journal of Radiation Research and Radiation Processing, 2009,27(3):129-132.
PAN Xiaosong, SHI Yujia, YAO Yimin, et al. Progress of research on activation function of NK cell exposed to low dose radiation in adoptive cellular immunotherapy[J]. Journal of Radiation Research and Radiation Processing, 2009,27(3):129-132.DOI:
Natural killer cells is an important immunological factor in killing malignant cells. Low dose radiation can enhance proliferation and biological activity of NK cell. The involvement of P38MAPK signal pathway and endogenous glutathione induced by LDR may be the probable mechanism. Natural killer cell, especially adherent natural killer cell, is the preferential choice for adoptive cellular immunotherapy, which has a remarkable foreground in malignancy therapy.