造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨

孙慧斌; 刘及; 李荣贵

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造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨

更新时间：2023-04-23

- 造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨
- AN APPROACH OF RADIOSENSITIVITY OF THE CFU-F IN THE BONE MARROW AND ITS SUBPOPULATION CLASSIFICATION
- 辐射研究与辐射工艺学报 1989年7卷第3期页码：1-4
- 作者机构：
  
  1.白求恩医科大学，长春
- 作者简介：
- 基金信息：
  
  中国科学院科学基金资助课题
- DOI：
  中图分类号：
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孙慧斌, 刘及, 李荣贵. 造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨[J]. 辐射研究与辐射工艺学报, 1989,7(3):1-4.

Sun Huibin, Liu Ji, Li Ronggui. AN APPROACH OF RADIOSENSITIVITY OF THE CFU-F IN THE BONE MARROW AND ITS SUBPOPULATION CLASSIFICATION[J]. Journal of Radiation Research and Radiation Processing, 1989,7(3):1-4.
孙慧斌, 刘及, 李荣贵. 造血微环境与造血机能ⅩⅩⅨ.骨髓CFU-f的放射敏感性测定及其亚群分类探讨[J]. 辐射研究与辐射工艺学报, 1989,7(3):1-4. DOI：

Sun Huibin, Liu Ji, Li Ronggui. AN APPROACH OF RADIOSENSITIVITY OF THE CFU-F IN THE BONE MARROW AND ITS SUBPOPULATION CLASSIFICATION[J]. Journal of Radiation Research and Radiation Processing, 1989,7(3):1-4. DOI：

摘要

本文依据集落细胞密度进行了豚鼠骨髓CFU-f的剂量一存活曲线测定。结合有关放射生物学资料的分析和集落形态观察，证明该CFU-f为非均一性群体，可区分为致密型（D,0,=2.17 Gy， N= 1.14）和疏松型（D,0,=4.09 Gy， N=1.13）等两个放射敏感性不同的亚群。这一结果对于加深理解CFU-f的放射生物学特性和放射损伤与修复规律，探讨CFU-f的亚群分类有着重要意义。

Abstract

The cell survival curve of the CFU-f in the guinea-pig bone marrow, which is distinguished according to the cellular density of colony, is assayed. By the analysis of the relative data from the experiment and the observation of the morphology of colony, we have proved that there are two distinct subpopulations in radiosensitivity and colonial morphology among the CFU-f populations in the guinea-pig bone marrow. The dense cellular colony type subpopulation of the CFU-f:D,0,=2.17 Gy, N=1.14; the sparse cellular colony type subpopulation of the CFU-f:D,0,=4.09 Gy, N=1.13. The studies may have important implication in acquiring a better understanding of the characteristics of the radiation biology as well as the rule of the radiation injury and recovery of the CFU-f.

关键词

CFU-f放射敏感性CFU-f亚群

Keywords

CFU-fRadiosensitivitySubpopulation

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