低剂量<sup>60</sup>Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究

余璐; 高凤鸣

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低剂量⁶⁰Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究

更新时间：2023-04-23

- 低剂量⁶⁰Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究
- MALIGNANT TRANSFORMATION OF SYRIAN HAMSTER EMBRYO CELLS IN VITRO BY LOW-DOSE OF ⁶⁰Co γ-RAY COMBINED WITH FEMALE SEX HORMONES
- 辐射研究与辐射工艺学报 1991年9卷第1期页码：34-38
- 作者机构：
  
  1.卫生部工业卫生实验所，北京
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余璐, 高凤鸣. 低剂量⁶⁰Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究[J]. 辐射研究与辐射工艺学报, 1991,9(1):34-38.

Yu Lu, Gao Fengming. MALIGNANT TRANSFORMATION OF SYRIAN HAMSTER EMBRYO CELLS IN VITRO BY LOW-DOSE OF ⁶⁰Co γ-RAY COMBINED WITH FEMALE SEX HORMONES[J]. Journal of Radiation Research and Radiation Processing, 1991,9(1):34-38.
余璐, 高凤鸣. 低剂量⁶⁰Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究[J]. 辐射研究与辐射工艺学报, 1991,9(1):34-38. DOI：

Yu Lu, Gao Fengming. MALIGNANT TRANSFORMATION OF SYRIAN HAMSTER EMBRYO CELLS IN VITRO BY LOW-DOSE OF ⁶⁰Co γ-RAY COMBINED WITH FEMALE SEX HORMONES[J]. Journal of Radiation Research and Radiation Processing, 1991,9(1):34-38. DOI：

摘要

本实验应用金黄地鼠胚胎（SHE）细胞，研究了低剂量,60,Coγ线与雌性激素（EP）联合诱发细胞恶性转化的作用。实验结果表明两种因素联合应用，致癌作用加强。同时也证明，哺乳动物细胞的恶性转化是一个多阶段的生物学过程。

Abstract

Malignant transformation of Syrian hamster embryo(SHE) cells in vitro was induced by low-dose of ,60,Co γ-ray combined with EP. The transformation was not observed in the groups that the γ-rays or EP was given alone.,The results snggested that the combination of low-dose of γ-ray and EP may have the synergetic effect of carcinogenesis on cells in vitro. The results also showed that transformation of cells in vitro is a multistage processes.

关键词

金黄地鼠胚胎（SHE）细胞雌性激素（EP）γ射线

Keywords

Syrian Hamster Embryo cellFemale sex hormone (EP estradiol valerateand hydroxyprogesterone caproate)γ-ray

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低剂量60Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究

MALIGNANT TRANSFORMATION OF SYRIAN HAMSTER EMBRYO CELLS IN VITRO BY LOW-DOSE OF 60Co γ-RAY COMBINED WITH FEMALE SEX HORMONES

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摘要

Abstract

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references

低剂量⁶⁰Co γ射线与雌性激素联合诱发SHE细胞恶性转化的实验研究

MALIGNANT TRANSFORMATION OF SYRIAN HAMSTER EMBRYO CELLS IN VITRO BY LOW-DOSE OF ⁶⁰Co γ-RAY COMBINED WITH FEMALE SEX HORMONES