The method for entrapment of Baker's yeast cell with invertase activity by ,60,Co radiation-induced polymerization of acrylaminde has been studied.,Acrylaminde was used as a carrier and N, N'-methylene bisacrylamide as a cross-linking reagent. The influence of immobilized conditions (such as irradiation dose, polymerization temperature, amount of yeast and cross-linking reagent) on the enzymatic activity has been investigated. From the experiments it was found that the irradiation dose until 2×10,6,rad has not a significant effect on the enzymatic activity. The immobilized cell which was prepared according to the optimum conditions was not only elastic but also hard and exhibited higher activity recovery. After the repeated use 10 tims of batch reaction the enzymatic activity didn't change.