人尿集落刺激因子对受照射小鼠存活的影响

汪涛; 王洪云; 张军宁

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人尿集落刺激因子对受照射小鼠存活的影响

研究论文 | 更新时间：2023-05-04

- 人尿集落刺激因子对受照射小鼠存活的影响
- EFFECT OF COLONY STIMULATING FACTOR FROM HUMAN URINE ON SURVIVAL OF IRRADIATED MICE
- 辐射研究与辐射工艺学报 1995年13卷第2期页码：91-94
- 作者机构：
  
  1.苏州医学院，苏州　215007
- 作者简介：
- 基金信息：
  
  江苏省科委资助课题
- DOI：
  中图分类号：
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汪涛, 王洪云, 张军宁. 人尿集落刺激因子对受照射小鼠存活的影响[J]. 辐射研究与辐射工艺学报, 1995,13(2):91-94.

Wang Tao, Wang Hongyun, Zhang Junning. EFFECT OF COLONY STIMULATING FACTOR FROM HUMAN URINE ON SURVIVAL OF IRRADIATED MICE[J]. Journal of Radiation Research and Radiation Processing, 1995,13(2):91-94.
汪涛, 王洪云, 张军宁. 人尿集落刺激因子对受照射小鼠存活的影响[J]. 辐射研究与辐射工艺学报, 1995,13(2):91-94. DOI：

Wang Tao, Wang Hongyun, Zhang Junning. EFFECT OF COLONY STIMULATING FACTOR FROM HUMAN URINE ON SURVIVAL OF IRRADIATED MICE[J]. Journal of Radiation Research and Radiation Processing, 1995,13(2):91-94. DOI：

摘要

本实验证明人尿集落刺激因子（CSF）能明显地提高受照射小鼠存活率，并延长存活时间。用微孔板有限稀释法培养粒细胞证明人尿CSF能维持外周血粒细胞存活，且存活细胞数与CSF浓度有密切关系。在含有人尿CSF的条件下，骨髓粒-巨噬细胞存活数（CFU-GM）在培养12 d时较培养8 d者增多。

Abstract

It was shown that colony stimulating factor (CSF) extracted from human urine could increase survival rate obviously and prolonged survival time in irradiated mice. Using tissue culture mini-well plate by means of limiting dilution method, it was shown that with CSF the mature granulocytes in peripheral blood could be kept survival and the counts of them were closely correlated with the concentrations of CSF. With CSF (200 u/ml), in the bone marrow culture the numbers of granulocyte-macrophage colony forming unit (CFU-GM) at the 12th day were larger than that at the 8th day.

关键词

集落刺激因子（CSF）细胞存活粒-巨噬细胞集落（CFU-GM）造血功能

Keywords

Colony stimulating factor(CSF)Survival cellsGranulocyte-macrophage colony forming unit (CFU-GM)Haemopoietic function

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电离辐射作用后粒-巨噬细胞修复的特性