The development of <sup>177</sup>Lu labelled peptides

XU Qianlong; LI Fenglin; FENG Hejuan; SHI Haojie; TANG Xian

doi:10.11889/j.1000-3436.2025-0082

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The development of ¹⁷⁷Lu labelled peptides

REVIEW | 更新时间：2026-03-02

- The development of ¹⁷⁷Lu labelled peptides
- “This article introduces the research progress of 177Lu labeled peptide radiopharmaceuticals in the field of tumor therapy. Experts have explored strategies such as polymerization, dual targeted design, and blood half-life extension modification, providing a key technical path for improving targeted peptide tumor retention.”
- Journal of Radiation Research and Radiation Processing Vol. 44, Issue 1, Pages: 10102(2026)
- 作者机构：
  
  1.中国原子能科学研究院北京 102413
  2.重庆市万州粮油质量监督检验站重庆 404001
- 作者简介：
  
  XU Qianlong (male) was born in March 2000, graduated from Dalian University of Technology in July 2022 with a bachelor's degree. Now, he is a graduate student at the China Institute of Atomic Energy, focusing on radiopharmaceuticals
  LI Fenglin, professor, E-mail: lifenglin@ciae.ac.cn
  TANG Xian, senior engineer, E-mail: tangxian@ciae.ac.cn
- 基金信息：
  
  Surpported by the President's Fund Project of China Institute of Atomic Energy (CIAE)(YZ222501001204)
- DOI：10.11889/j.1000-3436.2025-0082
  CLC： R817.9
- Received：10 September 2025，
  
  Revised：2026-01-04，
  
  Accepted：04 January 2026，
  
  Published：20 February 2026
- 稿件说明：
移动端阅览
徐千龙, 李凤林, 冯荷娟, 等. ¹⁷⁷Lu标记多肽类放射性药物研究进展[J]. 辐射研究与辐射工艺学报, 2026, 44(1): 010102.

XU Qianlong, LI Fenglin, FENG Hejuan, et al. The development of ¹⁷⁷Lu labelled peptides[J]. Journal of Radiation Research and Radiation Processing, 2026, 44(1): 010102.
徐千龙, 李凤林, 冯荷娟, 等. ¹⁷⁷Lu标记多肽类放射性药物研究进展[J]. 辐射研究与辐射工艺学报, 2026, 44(1): 010102. DOI： 10.11889/j.1000-3436.2025-0082. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0082.

XU Qianlong, LI Fenglin, FENG Hejuan, et al. The development of ¹⁷⁷Lu labelled peptides[J]. Journal of Radiation Research and Radiation Processing, 2026, 44(1): 010102. DOI： 10.11889/j.1000-3436.2025-0082. CSTR： 32195.14.j.JRRRP.1000-3436.2025-0082.

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The development of 177Lu labelled peptides

DOI：10.11889/j.1000-3436.2025-0082

The development of ¹⁷⁷Lu labelled peptides