CAI Weibo, ZOU Zhenghui, Qiu Jianmin, et al. HORMESIS OF LOW DOSE RADIATION ON THE EXPRESSION OF CYTOKINES IN UMBILICAL CORD BLOOD[J]. Journal of Radiation Research and Radiation Processing, 2003,21(2):154-156.
CAI Weibo, ZOU Zhenghui, Qiu Jianmin, et al. HORMESIS OF LOW DOSE RADIATION ON THE EXPRESSION OF CYTOKINES IN UMBILICAL CORD BLOOD[J]. Journal of Radiation Research and Radiation Processing, 2003,21(2):154-156.DOI:
The paper studies hormesis of low dose radiation (LDR)in the expression of cytokines in umbilical cord blood (UCB). 1h after irradiation of UCB with 5cGy of ,226,Ra γ-rays, the levels of IL-2, IL-8 EPO and SOD-1 were determined by radioimmunoassay (RIA). Compared with the control (0Gy), the levels of all the assayed cytokines in the irradiated samples were up-regulated, with significant differences for IL-2, IL-8 and SOD-1 (,p,<,0.05) and very significant difference for EPO (,p,<,0.01). LDR with ,226,Ra γ-rays could induce hormesis as to the expression of IL-2, IL-8, EPO and SOD-1 in UCB.
Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Science