PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N<sup>+</sup> IONS,UV AND <sup>60</sup>Co-γ ON THE GENTAMYCIN YIELD OF <italic style="font-style: italic">MICROMONOSPORA PURPUREA</italic>

WU Jian; SU Mingjie; DAI Guifu; WANG Weidong; ZHANG Shu; LI Zongwei; WANG Yanping; QIN Guangyong; HUO Yuping; YUAN Tianyang; YAN Xin; GAN Chongjie

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PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N⁺ IONS,UV AND ⁶⁰Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA

更新时间：2023-03-30

- PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N⁺ IONS,UV AND ⁶⁰Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA
- Journal of Radiation Research and Radiation Processing Vol. 21, Issue 2, Pages: 120-124(2003)
- 作者机构：
  
  1.郑州大学离子束生物工程省重点实验室　郑州　450052
  2.开封制药厂　开封　475003
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WU Jian, SU Mingjie, DAI Guifu, et al. PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N⁺ IONS,UV AND ⁶⁰Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA. [J]. Journal of Radiation Research and Radiation Processing 21(2):120-124(2003)
DOI：

WU Jian, SU Mingjie, DAI Guifu, et al. PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N⁺ IONS,UV AND ⁶⁰Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA. [J]. Journal of Radiation Research and Radiation Processing 21(2):120-124(2003) DOI：

摘要

研究了以庆大霉素生产菌绛红小单孢菌为供试菌株，比较了低能N,+,离子、紫外线和,60,Co γ 射线对绛红小单孢菌的剂量存活效应和诱变效果。结果发现，N,+,离子注入的存活曲线与紫外线、,60,Co γ 射线辐照不同，即紫外线，,60,Co γ 射线照射绛红小单孢菌的剂量存活曲线均是指数曲线，而N,+,离子注入呈复杂下降、上升、再下降的趋势,而且3种辐射在诱变效应上也有很大的差异。在相同死亡率条件下，紫外线诱变率低，但正变多于负变，而 γ 射线诱变率高，负变远远多于正变。适当剂量的N,+,离子注入表现出诱变率高、正变率高及正变幅度大的特点，效果更像紫外+LiCL的复合诱变。并确定了N,+,离子注入绛红小单孢菌的适宜诱变剂量是在存活率高峰处附近。

Abstract

The effect of 30 keV N,+, ions, UV and ,60,Co γ-rays on the survival and the gentamycin yield of ,Micromonospora purpurea, were investigated. A saddle-like survival curve was found ,Micromonospora purpurea, treated with N,+, ions, whereas the curves of those irradiated by UV and ,60,Co γ-rays were exponential, comparisons of the induction indexes indicated that the N,+, irradiation was more advantageous than UV and the γ-rays. Based on the experiments, it is concluded that induction doses of 0.5~1×10,16, /cm,2, i,e. the doses correlating to the peaks of the survival curve, are suitable for high yield of gentamycin.

关键词

离子注入绛红小单孢菌紫外线60Co γ 射线诱变庆大霉素

Keywords

Ion implantationMicromonospora purpureaUV60Co γNutationGentamycin

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PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N+ IONS,UV AND 60Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA

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摘要

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PRELIMINARY STUDY ON THE EFFECTS OF LOW ENERGY N⁺ IONS,UV AND ⁶⁰Co-γ ON THE GENTAMYCIN YIELD OF MICROMONOSPORA PURPUREA