The work is to investigate the effects of electromagnetic pulses (EMP) irradiation on the procreative system and to provide references for protecting EMP irradiation. BALB/C female or male mice were exposed to EMP radiation (95.41kVm,-1, field intensity, 3×10,6, and 4×10,6, pulses). Using the method of embryos teratology, BALB/C female mice were examined to pregnancy rate, the numbers of embryos and gender ratio after the exposed female or male mice mated with the shamed male or female respectively at the 1day and 2 month. For part of the EMP 3×10,6, pulses exposed group, the birth filial generation and learning ability of filial generation was tested with Y type electricity labyrinth, and when the filial grew up, their reaction latency for thermal nociception was tested on a 50℃ surface. In comparison to the sham control, pregnancy rate decreased with the female group exposed to 3×10,6, pulses EMP radiation and mated 1d after the exposure, and fetal deaths rate increased with the 4×10,6, pulses EMP irradiation and 1d mated group, resorption embryos rate increased (,p,<,0.05) with the exposed and 2 month mated male or female whereas, the other indexes didn’t change. Learning times of the filial generation whose either parent had been exposed increased distinctly with the control. The first latency on filial generation of the exposed female prolonged comparing to the control, but no significant differences were found in the other indexes. These results suggest that the EMP irradiation can induce some degree of injury on procreative system of mice, causing decreased pregnancy rate, increased fetal death rate and resorption embryos rate, and decreased learning ability of the filial generation. However, there were no evidence for effects of the EMP exposure on nociception of the filial generation. Further investigations are necessary to elucidate mechanisms of the EMP irradiation.