THE STUDY OF EFFECTS OF γ RAY COMBINED WITH ELECTROMAGNETIC FIELD ON HL-60 CELLS

LIU Xiaoqiu; ZHAO Wenzheng; ZHAO Ajin

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THE STUDY OF EFFECTS OF γ RAY COMBINED WITH ELECTROMAGNETIC FIELD ON HL-60 CELLS

更新时间：2023-04-07

- THE STUDY OF EFFECTS OF γ RAY COMBINED WITH ELECTROMAGNETIC FIELD ON HL-60 CELLS
- Journal of Radiation Research and Radiation Processing Vol. 20, Issue 1, Pages: 77-80(2002)
- 作者机构：
  
  1.中国医学科学院放射医学研究所　天津　300192
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LIU Xiaoqiu, ZHAO Wenzheng, ZHAO Ajin. THE STUDY OF EFFECTS OF γ RAY COMBINED WITH ELECTROMAGNETIC FIELD ON HL-60 CELLS. [J]. Journal of Radiation Research and Radiation Processing 20(1):77-80(2002)
DOI：

LIU Xiaoqiu, ZHAO Wenzheng, ZHAO Ajin. THE STUDY OF EFFECTS OF γ RAY COMBINED WITH ELECTROMAGNETIC FIELD ON HL-60 CELLS. [J]. Journal of Radiation Research and Radiation Processing 20(1):77-80(2002) DOI：

摘要

采用了细胞计数、细胞形态学、流式细胞仪分析方法，用,137,Cs照射源，剂量4Gy，磁场强度10MT，频率250Hz照射人早幼粒白血病细胞（HL—60细胞），研究了γ射线与电磁辐射联合对白血病细胞的作用。结果表明，单独γ射线和单独磁场照射均能不同程度地杀伤HL—60细胞，但,γ,射线与电磁辐射联合作用杀伤HL—60细胞能力更强。电磁场能增加γ射线杀伤HL—60细胞是通过增加,γ,射线诱导HL—60细胞凋亡的发生。

Abstract

By using viable cell count,cell morphology examination and flow cytometry analysis,We studied the effects of γ ray combined with electromagnetic field on HL — 60 cells. Cells were exposed to 4Gy γ irradiation from ,137,Cs γ ray. The strength and frequency of the electromagnetic field were 10MT and 250Hz respectively. The combined effects of ,137,Cs irradiation with exposure to the electromagnetic field showed a greater effect than a simple additive one. The results suggest that electromagnetic field can increase apoptosis induction of HL—60 cells by ionizing radiation.

关键词

γ射线电磁辐射细胞凋亡HL—60细胞

Keywords

γ rayElectromagnetic radiationApoptosisHL — 60 cell

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