EFFECT OF LOW DOSE RADIATION ON cGMP LEVELS OF PINEAL GLAND IN MICE

LI Xiaofeng; MA Lin; ZHANG Ming; CHI Baorong

您当前的位置：

首页 >

文章列表页 >

EFFECT OF LOW DOSE RADIATION ON cGMP LEVELS OF PINEAL GLAND IN MICE

更新时间：2023-04-07

- EFFECT OF LOW DOSE RADIATION ON cGMP LEVELS OF PINEAL GLAND IN MICE
- Journal of Radiation Research and Radiation Processing Vol. 20, Issue 2, Pages: 158-160(2002)
- 作者机构：
  
  1.吉林大学第一医院　长春　130021
  2.吉林省肿瘤医院　长春　130012
  3.吉林大学神经内分泌研究所　长春　130021
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
LI Xiaofeng, MA Lin, ZHANG Ming, et al. EFFECT OF LOW DOSE RADIATION ON cGMP LEVELS OF PINEAL GLAND IN MICE. [J]. Journal of Radiation Research and Radiation Processing 20(2):158-160(2002)
DOI：

LI Xiaofeng, MA Lin, ZHANG Ming, et al. EFFECT OF LOW DOSE RADIATION ON cGMP LEVELS OF PINEAL GLAND IN MICE. [J]. Journal of Radiation Research and Radiation Processing 20(2):158-160(2002) DOI：

摘要

通过低剂量辐射免疫兴奋效应的动物模型，进一步探讨低剂量X射线全身照射对小鼠松果腺细胞cGMP的影响。采用放免分析法检测75mGy X射线全身照射后不同时间小鼠松果腺cGMP的时程变化。照射后4h cGMP含量开始下降，12h、18h显著下降（,p,<,0.01）,24h后开始增高，72h显著增高（,p,<,0.05）。低剂量电离辐射可促进小鼠松果腺细胞信息转导功能激活。

Abstract

In this study, the change of cGMP of pineal gland in mice were observed with low dose radiation(LDR). The time—course changes of cGMP were detected by radioimmunoassay after WBI with 75mGy X rays. It was shown that the levels of cGMP of pineal gland in mice began to decrease and reached its lowest peak at 18h ,(p,<,0.01) after WBI. and began to increase at 24h and reached its highest peak at 72h (,p,<,0.05). These results indicated that WBI with LDR could reduce to the cGMP levels of pineal gland cells in mice.

关键词

低剂量辐射小鼠松果腺cGMP

Keywords

Low dose radiationPineal gland in micecGMP

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Interventional effect of multiple LDR on splenocyte apoptosis and immunity on twelve-week diabetic rats

Effects of low priming dose irradiation on cell cycle arrest of HepG2 cells caused by high dose irradiation

HORMESIS OF LOW DOSE RADIATION ON THE EXPRESSION OF CYTOKINES IN UMBILICAL CORD BLOOD

ADVANCE OF STUDY ON HORMESIS OF LOW DOSE RADIATION

LOW DOSE RADIATION INDUCED PRODUCTS IN MOUSE SPLEEN AND THEIR BIOLOGICAL ACTIVITY

Related Author

No data

Related Institution

Department of Toxicology, School of Public Health, Jilin University

MH Radiobiology Research Unit, School of Public Health, Jilin University

Institute of Modern Physics, Chinese Academy of Sciences

Graduate School of Chinese Academy of Sciences

School of Life Science, Lanzhou University

⁰