THE CHANGES OF ULTRASTRUCTURE IN ASCITIC RETICULOCYTICSAROCMA CELLS AFTER γ-IRRADIATION
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THE CHANGES OF ULTRASTRUCTURE IN ASCITIC RETICULOCYTICSAROCMA CELLS AFTER γ-IRRADIATION
Journal of Radiation Research and Radiation ProcessingVol. 2, Issue 1, Pages: 41-45(1984)
作者机构:
1.中国医学科学院放射医学研究所
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Jiang Tienan, Yang Jingying, Meng Shanshan, et al. THE CHANGES OF ULTRASTRUCTURE IN ASCITIC RETICULOCYTICSAROCMA CELLS AFTER γ-IRRADIATION. [J]. Journal of Radiation Research and Radiation Processing 2(1):41-45(1984)
DOI:
Jiang Tienan, Yang Jingying, Meng Shanshan, et al. THE CHANGES OF ULTRASTRUCTURE IN ASCITIC RETICULOCYTICSAROCMA CELLS AFTER γ-IRRADIATION. [J]. Journal of Radiation Research and Radiation Processing 2(1):41-45(1984)DOI:
THE CHANGES OF ULTRASTRUCTURE IN ASCITIC RETICULOCYTICSAROCMA CELLS AFTER γ-IRRADIATION
本文用扫描电镜和透射电镜观察网状细胞肉瘤SRS于γ线照射后超微结构的变化。瘤细胞经1000~5000 rad γ线照射后3小时,扫描电镜下可见其表面皱折减少,变细;微绒毛也减少,变粗,末端膨大,呈鼓锤状。5000 rad照射后,还见瘤细胞表面膜破溃和脱落。透射电镜下可见线粒体,高尔基氏器,核染色质和核仁均发生明显的退行性变化。可见SRS经γ线照射后早期,细胞原浆膜系统即发生明显变化
Abstract
The changes of ultrastructure in ascitic reticulocytic sarcoma cells (SRS) after γ-ray irradiation were studied with scanning and transmission electron microscopes. Various alterations at the cell surface membrane could be seen under the scanning electron microscope 3 hours after γ-ray irradiation with doses of 1000~5000 rad. Folds decreased in number and thinned. Villi also decreased but thickened with enlarged ends expanded as drumsticks. The surface membrane ulcerated and fell off after a 5000 rad irradiation. Obvious degeneration of mitochondrias, Golgi apparatuses, chromatin and nucleoli occured. All these revealed that the plasma membrane system of SRS changed significantly in the early period after γ-ray irradiation.
关键词
腹水型网状织细胞肉瘤细胞膜超微结构扫描电镜透射电镜60Co γ线照射
Keywords
Ascitic reticulosarcomaCell membraneUltrastructureScanning electron microscopeTransmission electron microscope60Co γ-ray Irradiation