Fluoropolymer F-46 may be crosslinked by irradiation under vacuum and a temperature below or near its melting point. It leads to formation of network macromolecules. The presence of network structure of radiation crosslinked F-46 was proved by the following facts: gel formation, appearance of rubbery plateau region and a more closely packing condition of molecular aggregation. The high temperature property of radiation crosslinked F-46 shows beneficial improvement.,The radiation crosslinking of F-46 follows the theory of random crosslinking. The dose of gelation is decreased with the increasing of temperature. The radiation crosslinking G value is increased with the increasing of temperature, at 240℃ the G value is 1.16. The mobility of polymer chain is increased with the temperature and it will promote radiation crosslinking of fluoropolymer F-46.