The change in structure of irradiated primaquine phosphate with doses of 0.75-10 Mrads don't be observed. The transfer action of energy of quinolyl in irradiation process is considerable due to quinolyl resonance stabilization. As a result of this action, during irradiated PVA for contained primaquine phosphate, radiation degradation of PVA can be decreased, but the mechanism of degradation don't be influenced. The effects of the different content of primaquine phosphate on various parameters of degradation have been studied in this work and the relationship of straight line is obtained in them.