THE EFFECTS OF IONIZING RADIATION ON PHA-ACTIVATED MICRONUCLEAR FREQUENCY OF LYMPHOCYTES IN RABBITS

Yang Jiakuan; Cheng Wenying; Ding Zhisheng; Cai Rongmei; Xu Ping; Luo Weihua; Zhu Bingchai; Zhang Hongyuan; Jia Fuxing; Lu Jiaben

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THE EFFECTS OF IONIZING RADIATION ON PHA-ACTIVATED MICRONUCLEAR FREQUENCY OF LYMPHOCYTES IN RABBITS

更新时间：2023-04-23

- THE EFFECTS OF IONIZING RADIATION ON PHA-ACTIVATED MICRONUCLEAR FREQUENCY OF LYMPHOCYTES IN RABBITS
- Journal of Radiation Research and Radiation Processing Vol. 5, Issue 2, Pages: 19-22(1987)
- 作者机构：
  
  1.上海医科大学放射医学研究所
  2.海军医学研究所
- 作者简介：
- 基金信息：
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Yang Jiakuan, Cheng Wenying, Ding Zhisheng, et al. THE EFFECTS OF IONIZING RADIATION ON PHA-ACTIVATED MICRONUCLEAR FREQUENCY OF LYMPHOCYTES IN RABBITS. [J]. Journal of Radiation Research and Radiation Processing 5(2):19-22(1987)
DOI：

Yang Jiakuan, Cheng Wenying, Ding Zhisheng, et al. THE EFFECTS OF IONIZING RADIATION ON PHA-ACTIVATED MICRONUCLEAR FREQUENCY OF LYMPHOCYTES IN RABBITS. [J]. Journal of Radiation Research and Radiation Processing 5(2):19-22(1987) DOI：

摘要

本文报道了家兔经整体照射或离体血照射100、200、300和400拉德后PHA激活的淋巴细胞微核率变化。结果表明，在这两种照射条件下，其微核率均随照射剂量增加而增高。两者间没有显著差别。照射后2小时，微核率即见增高，2周内维持在一恒定水平，第4周时开始减低。

Abstract

In this paper, the change of lymphocytes micronuclear frequency in rabbits IN VIVO and IN VITRO irradiated by 100, 200, 300 and 400 rads is reported. The results indicate that micronuclear frequency was increased with the dose of radiation in both conditions mentioned above, but there was no marked difference. Again, these results show that the lymphocytes micronuclear frequency used as a biodosimeter was completely possible.,The lymphocytes micronulear frequency increased immediately 2 hours later after radiation and the frequency increase maintained for 2 weeks, starting from 4 th week the micronuclear frequency was reduced. All these results were discussed.

关键词

微核辐射生物剂量计放射效应

Keywords

MicronucleiRadiafion Biological dosimeterRadiation effect

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