DYNAMIC OBSERVATION ON THE FUNCTIONAL CHANGE OF BONE MARROW VESSELS INTHE MICE IRRADIATED WITH 10 Gy γ- OR X-RAYS

Chen Jiapei; Liu Xiuying

您当前的位置：

首页 >

文章列表页 >

DYNAMIC OBSERVATION ON THE FUNCTIONAL CHANGE OF BONE MARROW VESSELS INTHE MICE IRRADIATED WITH 10 Gy γ- OR X-RAYS

更新时间：2023-04-23

- DYNAMIC OBSERVATION ON THE FUNCTIONAL CHANGE OF BONE MARROW VESSELS INTHE MICE IRRADIATED WITH 10 Gy γ- OR X-RAYS
- Journal of Radiation Research and Radiation Processing Vol. 6, Issue 1, Pages: 21-23,10(1988)
- 作者机构：
  
  1.军事医学科学院放射医学研究所，北京
- 作者简介：
- 基金信息：
- DOI：
  CLC：
扫描看全文
Chen Jiapei, Liu Xiuying. DYNAMIC OBSERVATION ON THE FUNCTIONAL CHANGE OF BONE MARROW VESSELS INTHE MICE IRRADIATED WITH 10 Gy γ- OR X-RAYS. [J]. Journal of Radiation Research and Radiation Processing 6(1):21-23,10(1988)
DOI：

Chen Jiapei, Liu Xiuying. DYNAMIC OBSERVATION ON THE FUNCTIONAL CHANGE OF BONE MARROW VESSELS INTHE MICE IRRADIATED WITH 10 Gy γ- OR X-RAYS. [J]. Journal of Radiation Research and Radiation Processing 6(1):21-23,10(1988) DOI：

摘要

检测静脉注射伊文思蓝后骨髓及血浆中染料含量并算出骨髓内血浆和全血含量的多少，可反映血管充盈好坏，血管壁通透性高低以及血窦壁破坏出血区域的大小等骨髓血管机能状况。实验结果表明，10 Gy γ线全身照射后6小时始，骨髓中伊文思蓝含量、血浆含量和全血含量明显增多。3天达峰值。照后10天仍明显高于正常。10 GyX线局部照射区骨髓血管机能呈双相改变。早期变化与全身照射后基本相仿，骨髓内染料滞留量及血浆全血含量均显著高于正常。照后晚期则各项指标可低于正常。

Abstract

The functional condition of bone marrow vessels was investigated by estimating the content of Evan's Blue, the plasma volume and the total blood volume in the bone marrow of the mice iv injected with Evan's Blue.,The results showed that 6 hr later after 10 Gy total body irradiation the injuries of bone marrow vessels could be observed. It reached the peak at the 3 rd day post-irradiation. on the 10th day post-exposure, the functional condition of bone marrow vessels remained abnormal. At early stage after a local X-irradiation, the damagcs of bone marrow vessels occured. They were similar to that after total body irradiation. At the late stage, the content of dye, the plasma volume and the total blood volume were below the control level. The significance of this finding in hemopoletic failure after irradiation was discussed.

关键词

照射血管机能变化

Keywords

irradiationfunctional change of vessels

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of CpG-ODN combined with radiation on micronuclei cell of the human intestinal crypt epithelial cell

THE CHARACTERS OF PATHOLOGY AND ULTRASTRUCTURE OF FIBROBLASTS IN NORMAL WOUND AND RADIATION-COMBINED WOUND HEALING

THE PRELIMINARY STUDY OF THE RELATIONSHIP BETWEEN GLUTATHIONE CONTENT IN HUMAN SGC7901 CELL LINE PRETREATED WITH RADIOSENSITIZER AND ITS SUFFERED RADIATION DOSE

EFFECTS OF INTERFERON-γ AND DEXAMETHASONE ON GROWTH OF NORMAL AND STIMULATED FIBROBLASTS BY 5-HYDROXYTRAPTAMINE

Related Author

No data

Related Institution

Department of Radiation Medicine, Faculty of Navy Medicine, Second Military Medical University

Institute of Radiation Medicine, Academy of Military Medical Sciences

Shanghai Institute of Radiation Medicine, Fudan University

⁰