PRIMARY RESULTS IN IRRADIATING STREPTOMYCES KANAMYCETICUS WITH FAST NEUTRON AND HIGH ENERGY ELECTORN

Tan Fusheng; Xin Luyong; Zhou Hongyan

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PRIMARY RESULTS IN IRRADIATING STREPTOMYCES KANAMYCETICUS WITH FAST NEUTRON AND HIGH ENERGY ELECTORN

更新时间：2023-04-23

- PRIMARY RESULTS IN IRRADIATING STREPTOMYCES KANAMYCETICUS WITH FAST NEUTRON AND HIGH ENERGY ELECTORN
- Journal of Radiation Research and Radiation Processing Vol. 6, Issue 1, Pages: 61-64,37(1988)
- 作者机构：
  
  1.北京第二制药厂，北京
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Tan Fusheng, Xin Luyong, Zhou Hongyan. PRIMARY RESULTS IN IRRADIATING STREPTOMYCES KANAMYCETICUS WITH FAST NEUTRON AND HIGH ENERGY ELECTORN. [J]. Journal of Radiation Research and Radiation Processing 6(1):61-64,37(1988)
DOI：

Tan Fusheng, Xin Luyong, Zhou Hongyan. PRIMARY RESULTS IN IRRADIATING STREPTOMYCES KANAMYCETICUS WITH FAST NEUTRON AND HIGH ENERGY ELECTORN. [J]. Journal of Radiation Research and Radiation Processing 6(1):61-64,37(1988) DOI：

摘要

我们曾多次进行快中子、高能电子辐射处理卡那菌株。实践证明，当选择适宜的诱变剂量时，如：高能电子为0.1～0.2 KGy，快中子为1～8×10,12,中子数／cm,2,，具有较高的诱变效应。除了选择诱变剂量外，诱变效应还与菌株的敏感性、处理方法、筛选条件等有关。快中子、高能电子诱发产生的新菌株，摇瓶效价提高10.34～30.8%，投产后产量提高4.07～5.23%。

Abstract

We carried out irradiation of kanamycin strain with fast neutron and high energy electron for many times. Our practice proved, when the selected mutagenic doses were suitable, for example, 0.10~0.20 kGy for high energy electron and 1~8×10,12, No. of neutron/cm,2, for fast neutron, there were more high mutagenic effects. Besides the suitable mutagenic dosess, the mutagenic effects were in connection with strain sensitivity, irradiation method, selection condition etc. By electron irradiation mutagenic treatment of kanamycin strain, a new kind strain was obtained. Its potency of shak bottle has been increased 10.34~30.8% and the production yield has been increased 4.07~5.23%.

关键词

卡那霉素辐射诱变

Keywords

KamaycinIrradiationMutagenisis

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