EFFECT OF GAMMA IRRADIATION ON ERYTHROCYTE PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY AND ERYTHROCYTE MEMBRANE LIPID PEROXIDATION IN VITRO AND IN VIVO

Kang Xin; Fang Yunzhong; Chen Jizhong

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EFFECT OF GAMMA IRRADIATION ON ERYTHROCYTE PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY AND ERYTHROCYTE MEMBRANE LIPID PEROXIDATION IN VITRO AND IN VIVO

更新时间：2023-04-23

- EFFECT OF GAMMA IRRADIATION ON ERYTHROCYTE PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY AND ERYTHROCYTE MEMBRANE LIPID PEROXIDATION IN VITRO AND IN VIVO
- Journal of Radiation Research and Radiation Processing Vol. 7, Issue 3, Pages: 60-63(1989)
- 作者机构：
  
  1.军事医学科学院放射医学研究所，北京
- 作者简介：
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Kang Xin, Fang Yunzhong, Chen Jizhong. EFFECT OF GAMMA IRRADIATION ON ERYTHROCYTE PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY AND ERYTHROCYTE MEMBRANE LIPID PEROXIDATION IN VITRO AND IN VIVO. [J]. Journal of Radiation Research and Radiation Processing 7(3):60-63(1989)
DOI：

Kang Xin, Fang Yunzhong, Chen Jizhong. EFFECT OF GAMMA IRRADIATION ON ERYTHROCYTE PURINE NUCLEOSIDE PHOSPHORYLASE ACTIVITY AND ERYTHROCYTE MEMBRANE LIPID PEROXIDATION IN VITRO AND IN VIVO. [J]. Journal of Radiation Research and Radiation Processing 7(3):60-63(1989) DOI：

摘要

本文报道离体和整体照射对大鼠红细胞嘌呤核苷磷酸化酶活力及红细胞膜脂质过氧化值的影响。其结果为：将大鼠抗凝血离体照射0，10，50和100 Gy以及全身照射8.5 Gy后第1、3、5 d，该酶活力下降而膜脂过氧化值却增加。作者推测，照射后酶活力的变化和脂质过氧化作用有关。

Abstract

The effect of ionizing irradiation on erythrocyte purine nucleoside phosphorylase and erythrocyte membrane lipid peroxidation have been comparatively studied in vitro and in vivo.,After irradiation of the heparinized rat blood with 0,10,50, and 100 Gy and during the different days following the whole-body exposure to 8.5 Gy, PNP activities decreased whereas erythrocyte membrane lipid peroxidation increased. These results are seemly shown the relationship existing between erythrocyte PNP activity and membrane lipid peroxidation.

关键词

离体照射全身照射红细胞嘌呤核苷磷硝化酶脂质过氧化

Keywords

Radiation in vitroWhole-body irradiationErythrocyte purine nucleoside phosphorylaseLipid peroxidation

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