EFFECTS OF γ-IRRADIATION ON LIPID PEROXIDATION IN RATS AND HUMANS

Wang Chongdao; Lin Xingcheng; Zhu Yuyu; Xu Changshao; Yao Daoyuah; Gao Yaoming; Yu Zhiying

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EFFECTS OF γ-IRRADIATION ON LIPID PEROXIDATION IN RATS AND HUMANS

更新时间：2023-04-23

- EFFECTS OF γ-IRRADIATION ON LIPID PEROXIDATION IN RATS AND HUMANS
- Journal of Radiation Research and Radiation Processing Vol. 7, Issue 4, Pages: 47-49(1989)
- 作者机构：
  
  1.苏州医学院，苏州
  2.苏州医学院附属一院，苏州
- 作者简介：
- 基金信息：
- DOI：
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Wang Chongdao, Lin Xingcheng, Zhu Yuyu, et al. EFFECTS OF γ-IRRADIATION ON LIPID PEROXIDATION IN RATS AND HUMANS. [J]. Journal of Radiation Research and Radiation Processing 7(4):47-49(1989)
DOI：

Wang Chongdao, Lin Xingcheng, Zhu Yuyu, et al. EFFECTS OF γ-IRRADIATION ON LIPID PEROXIDATION IN RATS AND HUMANS. [J]. Journal of Radiation Research and Radiation Processing 7(4):47-49(1989) DOI：

摘要

本文报道了藉改良的TBA法测定大鼠经10Gyγ线全身一次性照射72h后某些组织中的LPO变化以及22例恶性肿瘤患者接受总剂量为64～150 Gy的γ线分次局部照射前后血清中LPO含量变化。结果发现照后大鼠肝、脾、脑和肾中LPO含量显著升高，其中尤以脾为最；恶性肿瘤患者照射前后血清中LPO含量的差别也十分显著。

Abstract

This paper describes the changes of LPO contents of some tissues in rats before and 72 hr after whole-body radiation with single 10 Gy dose of γ-irradiation and of serum LPO levels in 22 patients with malignant tumours before and after radiotherapy with 64-150 Gy total dose of fractional local γ-irradiation. LPO in the animal tissues and the human sera were determined by the modified spectrophotometry of TBA.,The results showed that LPO contents of liver, spleen, brain and kidney in rats dramatically increased after radiation, and among them the change of LPO of spleen was the most remarkable. There was a marked difference between LPO levels in patients with malignant tumours before and after radiation exposure.

关键词

LPO大鼠恶性肿瘤患者改良的TBA法

Keywords

LPORatsPatients with malignant tumoursModified spectrophotometry of TBA

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