CAMPARISON OF THE PHOTOSENSITIVE DAMAG OF THREE DRUGS OF PORPHYRINS ON CALF THYMUS DNA

Xu Yiming; Xu Guori; Yang Xianchun; Zhang Zhiyi

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CAMPARISON OF THE PHOTOSENSITIVE DAMAG OF THREE DRUGS OF PORPHYRINS ON CALF THYMUS DNA

更新时间：2023-04-23

- CAMPARISON OF THE PHOTOSENSITIVE DAMAG OF THREE DRUGS OF PORPHYRINS ON CALF THYMUS DNA
- Journal of Radiation Research and Radiation Processing Vol. 7, Issue 4, Pages: 60-62(1989)
- 作者机构：
  
  1.中国科学院生物物理所，北京
  **.北京石油化工科学院
- 作者简介：
- 基金信息：
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Xu Yiming, Xu Guori, Yang Xianchun, et al. CAMPARISON OF THE PHOTOSENSITIVE DAMAG OF THREE DRUGS OF PORPHYRINS ON CALF THYMUS DNA. [J]. Journal of Radiation Research and Radiation Processing 7(4):60-62(1989)
DOI：

Xu Yiming, Xu Guori, Yang Xianchun, et al. CAMPARISON OF THE PHOTOSENSITIVE DAMAG OF THREE DRUGS OF PORPHYRINS ON CALF THYMUS DNA. [J]. Journal of Radiation Research and Radiation Processing 7(4):60-62(1989) DOI：

摘要

本工作用激光喇曼光谱从分子水平就三种卟啉类药物对小牛胸腺DNA的光敏损伤进行了比较。结果表明，对小牛胸腺DNA损伤最强的是光卟啉YHPD，而PhotofrinⅡ和血卟啉BHPD分别居第二、第三位。

Abstract

In this work, the photosensitive damages of three drugs of Porphyrins (YHPD, BHPD and Photofrin Ⅱ) on Calf Thymus DNA were compared by Laser Raman spectroscopy at molecular level. It is indicated that the damage of YHPD on Calf Thymus DNA is the strongest, and then the Photofrin Ⅱ, and the third BHPD.

关键词

卟啉类光敏药物DNA光敏损伤喇曼光谱激光

Keywords

Photosensitive drugs of PorphyrinsDNAPhotosensitive damagesRaman spectroscopyLaser

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