STUDY ON THE RADIOSENSITIZING EFFECT OF CARBOXYETHYLGERMANII SESQUIOXIDUM

Meng Xiangshun; Zhao Fang; Gao Jianguo; Zheng Xiulong; Li Shuan; Fang Jiasheng; Shi Wenping; Huang Bencai

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STUDY ON THE RADIOSENSITIZING EFFECT OF CARBOXYETHYLGERMANII SESQUIOXIDUM

更新时间：2023-04-23

- STUDY ON THE RADIOSENSITIZING EFFECT OF CARBOXYETHYLGERMANII SESQUIOXIDUM
- Journal of Radiation Research and Radiation Processing Vol. 9, Issue 3, Pages: 173-177(1991)
- 作者机构：
  
  1.第二军医大学，上海
  2.广州军区后勤部药物研究所，广州
  3.同济大学，上海
- 作者简介：
- 基金信息：
- DOI：
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Meng Xiangshun, Zhao Fang, Gao Jianguo, et al. STUDY ON THE RADIOSENSITIZING EFFECT OF CARBOXYETHYLGERMANII SESQUIOXIDUM. [J]. Journal of Radiation Research and Radiation Processing 9(3):173-177(1991)
DOI：

Meng Xiangshun, Zhao Fang, Gao Jianguo, et al. STUDY ON THE RADIOSENSITIZING EFFECT OF CARBOXYETHYLGERMANII SESQUIOXIDUM. [J]. Journal of Radiation Research and Radiation Processing 9(3):173-177(1991) DOI：

摘要

本文以体外培养的CHO细胞微核率的变化及荷S180小鼠为动物模型的体内实验，从不同剂量γ线照射、不同有机锗剂量及不同给药途径等方面研究了有机锗的放射增敏作用。结果表明，体内、体外实验的增敏比（SER值）分别为1.22和1.18。

Abstract

The radiosensitizing effect of carboxyethylgermanii sesquioxidum was determined by the frequency of micronuclei and regrowth delay. The results showed that the radiosensitization effect was observed under hypoxia condition and the value of sensitizing effect ratio SER) were 1.22 and 1.18 respectively in vivo and in vitro.

关键词

放射增敏剂倍半氧化羧乙基锗微核率再生长延迟SER值

Keywords

RadiosensitizerCarboxyethylgermanii sesquioxidumMicronucleiRegrowth delaySER value

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